ID   A0A4Y6N8X3_SALET        Unreviewed;       715 AA.
AC   A0A4Y6N8X3;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   13-NOV-2019, entry version 3.
DE   SubName: Full=Formate dehydrogenase H subunit alpha, selenocysteine-containing {ECO:0000313|EMBL:QEO55783.1};
GN   ORFNames=FOL37_22335 {ECO:0000313|EMBL:QEM66174.1}, FV315_20980
GN   {ECO:0000313|EMBL:QEO55783.1};
OS   Salmonella enterica subsp. enterica serovar Indiana.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=286783 {ECO:0000313|EMBL:QEO55783.1};
RN   [1] {ECO:0000313|EMBL:QEM66174.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FJC33 {ECO:0000313|EMBL:QEM66174.1};
RA   Fang L.;
RT   "Co-spread of plasmid-mediated and chromosomally encoded fosA3 gene
RT   with multiple important ARGs among Multi-Drug Resistant Salmonella
RT   from food animals.";
RL   Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:QEO55783.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=K16SI097 {ECO:0000313|EMBL:QEO55783.1};
RA   Moon D., Lim S.-K.;
RL   Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539;
CC         Evidence={ECO:0000256|SAAS:SAAS00648551};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|SAAS:SAAS00607242};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|SAAS:SAAS01108232}.
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DR   EMBL; CP041699; QEM66174.1; -; Genomic_DNA.
DR   EMBL; CP043564; QEO55783.1; -; Genomic_DNA.
DR   CDD; cd02790; MopB_CT_Formate-Dh_H; 1.
DR   CDD; cd02753; MopB_Formate-Dh-H; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR041925; CT_Formate-Dh_H.
DR   InterPro; IPR041924; Formate_Dh-H_N.
DR   InterPro; IPR006478; Formate_DH_asu.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR   InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; SSF50692; 1.
DR   TIGRFAMs; TIGR01591; Fdh-alpha; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR   PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
DR   PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
DR   PROSITE; PS00932; MOLYBDOPTERIN_PROK_3; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|SAAS:SAAS00418020};
KW   Iron {ECO:0000256|SAAS:SAAS00454562};
KW   Iron-sulfur {ECO:0000256|SAAS:SAAS00454505};
KW   Metal-binding {ECO:0000256|SAAS:SAAS00077323};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS01133048};
KW   Selenium {ECO:0000313|EMBL:QEO55783.1};
KW   Selenocysteine {ECO:0000313|EMBL:QEO55783.1}.
FT   DOMAIN        1     56       4Fe-4S Mo/W bis-MGD-type.
FT                                {ECO:0000259|PROSITE:PS51669}.
FT   NON_STD     140    140       Selenocysteine. {ECO:0000313|EMBL:
FT                                QEO55783.1}.
SQ   SEQUENCE   715 AA;  79212 MW;  159AF3532CF6B49F CRC64;
     MKKVVTVCPY CASGCKINLV VDNGKIVRAE AAQGKTNQGT LCLKGYYGWD FINDTQILTP
     RLKTPMIRRQ RGGKLESVSW DEALNYVAER LSAIKAKYGP DAIQTTGSSR GTGNETNYVM
     QKFARAVIGT NNVDCCARVU HGPSVAGLHQ SVGNGAMSNA INEIDNTDLV FVFGYNPADS
     HPIVANHVIN AKRNGAKIIV CDPRKIETAR IADMHIALKN GSNIALLNAM GHVIIEENLY
     DKAFVASRTE GFEEYSKIVE GYTPESVEEI TGVSAQEIRQ AARMYASAKS AAILWGMGVT
     QFYQGVETVR SLTSLAMLTG NLGKPSAGVN PVRGQNNVQG ACDMGALPDT YPGYQYVKFP
     ENREKFAKAW GVESLPAHTG YRISELPHRA AHGEVRAAYI MGEDPLQTDA ELSAVRKAFE
     DLELVIVQDI FMTKTASAAD VILPSTSWGE HEGVFSAADR GFQRFFKAVE PKWDLKTDWQ
     IISEIATRMG YPMHYNNTQE IWDELRHLCP DFYGATYEKM GELGYIQWPC RDTSDADQGT
     SYLFKEKFDT PNGLAQFFTC DWVAPIDKLT EEYPMVLSTV REVGHYSCRS MTGNCAALAA
     LADEPGYAQI NTADAARLGI EDEALVWVHS RKGKIITRAQ VSDRPNKGAI YMTYQWWIGA
     CNELVTENLS PITKTPEYKY CAVRVEPIAD QRAAEQYVID EYNKLKTRLR ESAMG
//