ID A0A4Y1XND1_9BACT Unreviewed; 406 AA. AC A0A4Y1XND1; DT 18-SEP-2019, integrated into UniProtKB/TrEMBL. DT 18-SEP-2019, sequence version 1. DT 24-JAN-2024, entry version 12. DE SubName: Full=Endonuclease {ECO:0000313|EMBL:BBL14259.1}; GN ORFNames=A6CPBBH3_08980 {ECO:0000313|EMBL:BBL14259.1}; OS Alistipes communis. OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; OC Alistipes. OX NCBI_TaxID=2585118 {ECO:0000313|EMBL:BBL14259.1, ECO:0000313|Proteomes:UP000317796}; RN [1] {ECO:0000313|Proteomes:UP000317796} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=6CPBBH3 {ECO:0000313|Proteomes:UP000317796}; RA Sakamoto M., Ikeyama N., Ogata Y., Suda W., Iino T., Hattori M., Ohkuma M.; RT "Alistipes onderdonkii subsp. vulgaris subsp. nov., Alistipes dispar sp. RT nov. and Alistipes communis sp. nov., isolated from human faeces, and RT creation of Alistipes onderdonkii subsp. onderdonkii subsp. nov."; RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP019739; BBL14259.1; -; Genomic_DNA. DR AlphaFoldDB; A0A4Y1XND1; -. DR Proteomes; UP000317796; Chromosome. DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro. DR Gene3D; 3.40.570.10; Extracellular Endonuclease, subunit A; 1. DR InterPro; IPR024361; BACON. DR InterPro; IPR001604; DNA/RNA_non-sp_Endonuclease. DR InterPro; IPR044929; DNA/RNA_non-sp_Endonuclease_sf. DR InterPro; IPR020821; Extracellular_endonuc_su_A. DR InterPro; IPR044925; His-Me_finger_sf. DR InterPro; IPR040255; Non-specific_endonuclease. DR PANTHER; PTHR13966:SF5; ENDONUCLEASE G, MITOCHONDRIAL; 1. DR PANTHER; PTHR13966; ENDONUCLEASE RELATED; 1. DR Pfam; PF19190; BACON_2; 1. DR Pfam; PF01223; Endonuclease_NS; 1. DR SMART; SM00892; Endonuclease_NS; 1. DR SMART; SM00477; NUC; 1. DR SUPFAM; SSF54060; His-Me finger endonucleases; 1. DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1. PE 4: Predicted; KW Endonuclease {ECO:0000313|EMBL:BBL14259.1}; KW Hydrolase {ECO:0000313|EMBL:BBL14259.1}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR640255-2}; KW Nuclease {ECO:0000313|EMBL:BBL14259.1}; Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..22 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 23..406 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5021221962" FT DOMAIN 184..394 FT /note="DNA/RNA non-specific endonuclease" FT /evidence="ECO:0000259|SMART:SM00892" FT DOMAIN 185..394 FT /note="Extracellular Endonuclease subunit A" FT /evidence="ECO:0000259|SMART:SM00477" FT ACT_SITE 249 FT /note="Proton acceptor" FT /evidence="ECO:0000256|PIRSR:PIRSR640255-1" FT BINDING 280 FT /ligand="Mg(2+)" FT /ligand_id="ChEBI:CHEBI:18420" FT /ligand_note="catalytic" FT /evidence="ECO:0000256|PIRSR:PIRSR640255-2" SQ SEQUENCE 406 AA; 45086 MW; 43061F03792FB836 CRC64; MQTHLLRQWL RLAVAAVAVF FAACGDSDGD AATARVESCE LERSSIVGGQ IASGEETASL RVIVEVSGSG QLNYTATITS GDWLSLSARD FSAAGRQRQG TVDSGENLLF FYYKANASAQ SRIATFTIAF DDGSAPYDFE LTQLAPNATD NPYDTPKQWP ELPAGKEETD YIYAAHYAKM NLKTVRNYSL CFDKKLRVAH WVAYPLHASY IGSLDRSEAW APDPKIPQQY QPALWLGGYQ NGNVYNRGHQ IPSKDRTTVE EMNKQTFYAS NMTPQRGQFN QNMWAALEAK VRSYVCPDTL YVVTGCYFAN LDESTKDKAG NVCPVPTNYF KVLLRTRDGE TGKRITDCKA SELKAIGFWV ANENGQQLGR QLCRSVAEIE KETGFTFFPD ADASVKAQNS PEQWGF //