ID A0A4W4HS28_ELEEL Unreviewed; 679 AA. AC A0A4W4HS28; DT 18-SEP-2019, integrated into UniProtKB/TrEMBL. DT 18-SEP-2019, sequence version 1. DT 13-NOV-2019, entry version 3. DE RecName: Full=TGc domain-containing protein {ECO:0000259|SMART:SM00460}; GN Name=LOC113569341 {ECO:0000313|Ensembl:ENSEEEP00000051738}; OS Electrophorus electricus (Electric eel) (Gymnotus electricus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Gymnotiformes; OC Gymnotoidei; Gymnotidae; Electrophorus. OX NCBI_TaxID=8005 {ECO:0000313|Ensembl:ENSEEEP00000051738, ECO:0000313|Proteomes:UP000314983}; RN [1] {ECO:0000313|Proteomes:UP000314983} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=24970089; RA Gallant J.R., Traeger L.L., Volkening J.D., Moffett H., Chen P.H., RA Novina C.D., Phillips G.N.Jr., Anand R., Wells G.B., Pinch M., RA Guth R., Unguez G.A., Albert J.S., Zakon H.H., Samanta M.P., RA Sussman M.R.; RT "Nonhuman genetics. Genomic basis for the convergent evolution of RT electric organs."; RL Science 344:1522-1525(2014). RN [2] {ECO:0000313|Proteomes:UP000314983} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=28695212; RA Traeger L.L., Sabat G., Barrett-Wilt G.A., Wells G.B., Sussman M.R.; RT "A tail of two voltages: Proteomic comparison of the three electric RT organs of the electric eel."; RL Sci. Adv. 3:e1700523-e1700523(2017). RN [3] {ECO:0000313|Ensembl:ENSEEEP00000051738} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2019) to UniProtKB. CC -!- COFACTOR: CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108; CC Evidence={ECO:0000256|PIRSR:PIRSR000459-2}; CC Note=Binds 1 Ca(2+) ion per subunit. CC {ECO:0000256|PIRSR:PIRSR000459-2}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSEEET00000052296; ENSEEEP00000051738; ENSEEEG00000024292. DR Proteomes; UP000314983; Unassembled WGS sequence. DR Gene3D; 2.60.40.10; -; 3. DR Gene3D; 3.90.260.10; -; 1. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR014756; Ig_E-set. DR InterPro; IPR038765; Papain-like_cys_pep_sf. DR InterPro; IPR002931; Transglutaminase-like. DR InterPro; IPR036985; Transglutaminase-like_sf. DR InterPro; IPR023608; Transglutaminase_animal. DR InterPro; IPR013808; Transglutaminase_AS. DR InterPro; IPR008958; Transglutaminase_C. DR InterPro; IPR036238; Transglutaminase_C_sf. DR InterPro; IPR001102; Transglutaminase_N. DR Pfam; PF00927; Transglut_C; 2. DR Pfam; PF01841; Transglut_core; 1. DR Pfam; PF00868; Transglut_N; 1. DR PIRSF; PIRSF000459; TGM_EBP42; 1. DR SMART; SM00460; TGc; 1. DR SUPFAM; SSF49309; SSF49309; 2. DR SUPFAM; SSF54001; SSF54001; 1. DR SUPFAM; SSF81296; SSF81296; 1. DR PROSITE; PS00547; TRANSGLUTAMINASES; 1. PE 4: Predicted; KW Calcium {ECO:0000256|PIRSR:PIRSR000459-2}; KW Complete proteome {ECO:0000313|Proteomes:UP000314983}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR000459-2}; KW Reference proteome {ECO:0000313|Proteomes:UP000314983}. FT DOMAIN 266 358 TGc. {ECO:0000259|SMART:SM00460}. FT ACT_SITE 274 274 {ECO:0000256|PIRSR:PIRSR000459-1}. FT ACT_SITE 332 332 {ECO:0000256|PIRSR:PIRSR000459-1}. FT ACT_SITE 355 355 {ECO:0000256|PIRSR:PIRSR000459-1}. FT METAL 395 395 Calcium. {ECO:0000256|PIRSR:PIRSR000459- FT 2}. FT METAL 397 397 Calcium. {ECO:0000256|PIRSR:PIRSR000459- FT 2}. FT METAL 443 443 Calcium. {ECO:0000256|PIRSR:PIRSR000459- FT 2}. FT METAL 448 448 Calcium. {ECO:0000256|PIRSR:PIRSR000459- FT 2}. SQ SEQUENCE 679 AA; 76360 MW; A2BB0E25A0B193B3 CRC64; LVQNLIVLTY IGSWDLACEF NNMDHHTELN GTDRLIVRRG QPFTVSLSLR SGSYQPGTHQ LRITADTGIA PMEEYGTRAV FGLSDVIDNT HWSAVVTSPP ADTITLSICS APDAPIGRYI LTLDSQIQFE LILLFNPWCP RDAVYMDSKD KLEEYVLAQD GIIYRGDAKY PVPLPWYFGQ FEDSILDICL RILDVNPKYQ RNPGKDCSGR RNPVYVTRVL SAMVNSNDRD NGVLVGCWKN SFEDGISPMS WKGSVNILRN WNSTSCMSVR YGQCWVFAAV ACTVSRALGI PCRVVTNYLS AHDTNTNLVI ERYYDEKGQL LNSTRDMIWN YHCWVESWMT RPDLKAGFDG WQASDPTPQE KSEGVYCCGP VPLQAIKEGE LTLKYDAPFV FAEVNADLET YLKYKDGSMK RLYDKSKVGQ KISTKSVGSD QREDITHLYK YAEGSDEERE VFQKANHQNK LLKQQDNTGL HITIKVSAEM RKGCDFDVFA LVTNSTSVDK KCRLVFASRA VAYDGTIGQE CGFKDLLNVE LPPGGERKVP LRLNYSKYCN AITQDNLIRL GALLIDYSTR DAILDMRTIV LENPEICIRI LGEPKVNRRL AAEVTLQNPL SEPLEACCFS IEGANLTGNK IPTRVEPGQE VKAKIYFTPT HCGVRKLLVD FNSDKLGHVK GFRNVIIGK //