ID A0A4W4G278_ELEEL Unreviewed; 322 AA. AC A0A4W4G278; DT 18-SEP-2019, integrated into UniProtKB/TrEMBL. DT 18-SEP-2019, sequence version 1. DT 17-JUN-2020, entry version 5. DE RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540}; GN Name=LOC113586946 {ECO:0000313|Ensembl:ENSEEEP00000031781}; OS Electrophorus electricus (Electric eel) (Gymnotus electricus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Gymnotiformes; OC Gymnotoidei; Gymnotidae; Electrophorus. OX NCBI_TaxID=8005 {ECO:0000313|Ensembl:ENSEEEP00000031781}; RN [1] {ECO:0000313|Ensembl:ENSEEEP00000031781} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=24970089; RA Gallant J.R., Traeger L.L., Volkening J.D., Moffett H., Chen P.H., RA Novina C.D., Phillips G.N.Jr., Anand R., Wells G.B., Pinch M., Guth R., RA Unguez G.A., Albert J.S., Zakon H.H., Samanta M.P., Sussman M.R.; RT "Nonhuman genetics. Genomic basis for the convergent evolution of electric RT organs."; RL Science 344:1522-1525(2014). RN [2] {ECO:0000313|Ensembl:ENSEEEP00000031781} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=28695212; RA Traeger L.L., Sabat G., Barrett-Wilt G.A., Wells G.B., Sussman M.R.; RT "A tail of two voltages: Proteomic comparison of the three electric organs RT of the electric eel."; RL Sci. Adv. 3:e1700523-e1700523(2017). RN [3] {ECO:0000313|Ensembl:ENSEEEP00000031781} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2019) to UniProtKB. CC -!- DOMAIN: A pair of annexin repeats may form one binding site for calcium CC and phospholipid. {ECO:0000256|RuleBase:RU003540}. CC -!- SIMILARITY: Belongs to the annexin family. CC {ECO:0000256|RuleBase:RU003540}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSEEET00000032165; ENSEEEP00000031781; ENSEEEG00000015058. DR Proteomes; UP000314983; Unassembled WGS sequence. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW. DR GO; GO:0004859; F:phospholipase inhibitor activity; IEA:InterPro. DR Gene3D; 1.10.220.10; -; 4. DR InterPro; IPR001464; Annexin. DR InterPro; IPR018502; Annexin_repeat. DR InterPro; IPR018252; Annexin_repeat_CS. DR InterPro; IPR037104; Annexin_sf. DR InterPro; IPR002388; ANX1. DR PANTHER; PTHR10502:SF17; PTHR10502:SF17; 1. DR Pfam; PF00191; Annexin; 4. DR PRINTS; PR00196; ANNEXIN. DR SMART; SM00335; ANX; 4. DR SUPFAM; SSF47874; SSF47874; 1. DR PROSITE; PS00223; ANNEXIN_1; 3. PE 3: Inferred from homology; KW Annexin {ECO:0000256|RuleBase:RU003540, ECO:0000256|SAAS:SAAS01228318}; KW Calcium {ECO:0000256|RuleBase:RU003540}; KW Calcium/phospholipid-binding {ECO:0000256|RuleBase:RU003540}; KW Reference proteome {ECO:0000313|Proteomes:UP000314983}; KW Repeat {ECO:0000256|RuleBase:RU003540, ECO:0000256|SAAS:SAAS01228293}. SQ SEQUENCE 322 AA; 35736 MW; B8C4AE5928F62DE5 CRC64; MSPSTVSSSC VLLQGKAPSK GSTPPYYGTI TPDPNFSASR DAAALQRAIE AKGVDESAIT EILARRTNAQ RQQIKAAYEN DTGKDLVKTL KSVLKSHYED TVVALLMNPA QYDAYELRQA MKGLGTNEKV LNEILGTRSN HEIRLLKTAF KEGKHPELEH NIKGDTSGHY ETALLALSKT LYEAGEKKIG TVYSVFIDIL TSRSEAQLCK IFKQYDKLGT QGFPKALEHE MKGDVEDCLM TLGKCLRCNS NMVLFECDAL TLQGAWANCN TLTRILVSRS EVDLKKILQE YKRMYGKTLQ EDINVETKGD YVKILLALCG DH //