ID A0A4V0IJ47_CAEEL Unreviewed; 834 AA. AC A0A4V0IJ47; DT 31-JUL-2019, integrated into UniProtKB/TrEMBL. DT 31-JUL-2019, sequence version 1. DT 18-SEP-2019, entry version 2. DE SubName: Full=DEGeneration of certain neurons {ECO:0000313|EMBL:VTW47533.1}; GN Name=deg-1 {ECO:0000313|EMBL:VTW47533.1, GN ECO:0000313|WormBase:C47C12.6e}; GN ORFNames=C47C12.6 {ECO:0000313|WormBase:C47C12.6e}, CELE_C47C12.6 GN {ECO:0000313|EMBL:VTW47533.1}; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; OC Caenorhabditis. OX NCBI_TaxID=6239 {ECO:0000313|EMBL:VTW47533.1, ECO:0000313|Proteomes:UP000001940}; RN [1] {ECO:0000313|EMBL:VTW47533.1, ECO:0000313|Proteomes:UP000001940} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2 {ECO:0000313|EMBL:VTW47533.1, RC ECO:0000313|Proteomes:UP000001940}; RX PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RA Sulson J.E., Waterston R.; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). CC -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel CC (TC 1.A.6) family. {ECO:0000256|RuleBase:RU000679, CC ECO:0000256|SAAS:SAAS00581569}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX284606; VTW47533.1; -; Genomic_DNA. DR WormBase; C47C12.6e; CE53486; WBGene00000950; deg-1. DR Proteomes; UP000001940; Chromosome X. DR InterPro; IPR004726; Deg-1. DR InterPro; IPR001873; ENaC. DR InterPro; IPR020903; ENaC_CS. DR PANTHER; PTHR11690; PTHR11690; 2. DR Pfam; PF00858; ASC; 1. DR PRINTS; PR01078; AMINACHANNEL. DR TIGRFAMs; TIGR00867; deg-1; 1. DR PROSITE; PS01206; ASC; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000001940}; KW Ion channel {ECO:0000256|RuleBase:RU000679, KW ECO:0000256|SAAS:SAAS00473180}; KW Ion transport {ECO:0000256|RuleBase:RU000679, KW ECO:0000256|SAAS:SAAS00110123}; KW Membrane {ECO:0000256|SAAS:SAAS00473191, ECO:0000256|SAM:Phobius}; KW Proteomics identification {ECO:0000213|EPD:A0A4V0IJ47}; KW Reference proteome {ECO:0000313|Proteomes:UP000001940}; KW Sodium {ECO:0000256|SAAS:SAAS00473235}; KW Sodium channel {ECO:0000256|RuleBase:RU000679, KW ECO:0000256|SAAS:SAAS00473207}; KW Sodium transport {ECO:0000256|RuleBase:RU000679, KW ECO:0000256|SAAS:SAAS00473179}; KW Transmembrane {ECO:0000256|RuleBase:RU000679, KW ECO:0000256|SAAS:SAAS00473187, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00473222, KW ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|RuleBase:RU000679, KW ECO:0000256|SAAS:SAAS00473201}. FT TRANSMEM 78 96 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 769 795 Helical. {ECO:0000256|SAM:Phobius}. FT REGION 154 180 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 201 220 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 344 437 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 154 174 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. SQ SEQUENCE 834 AA; 93964 MW; BDB1FA9D951076D3 CRC64; MSNHHSKTKK TSMLGREDYI YSHDITNKNK KEKLNGASKN NDYNQDDDDE TMKSKMMDFC DKTTAHGAKR VLIARNSFSK LMWGLIIFSF LLMFAYQASK LIFKFSAHEK ITDISLKFDD VEFPAITFCN LNPYKKSLVM MVPSIRDTMD VYDNAKTHSK SEGEKKKPKV SRKQHSDASQ QMVRELFAKE IEEGMVELKK SNKTLQSQNK SGRRRSQRSI ENRRYEAIEA HCKCVGNIGM ECIRFESPPR DPSSKCICTY DRDMEVAWPC FNISVWYDHE CPLCHDDGYC ESTLPSGTTS SDKWPCMCRN RGDTSERDDT PYCIGKAGVG KIEIRKLWLE NNMTTTSTTT TTTTTPPPTT TSTTTTTTTT PPPTTTVSTS TSTTSTTTTT TTTTTPRPTT TEKTTTTPRP TTSTTSTTTT THPPTTTTTP YPTRPNQRAI VSNPETIKAM GFQGMTDGVA MLTRAKENLM FTMAALSDKQ RIALSQSKHE FIEMCSFNGK ECDIDEDFRL HVDPEFGNCF TFNYDVNNNY TSSRAGPMYG IRVLLFVNTS DYMSTSESSG VRLAIHPPTE YPFPDTFGYS APVGFASSFG IKKKVMQRLP APYGECVETK KVVDRNYIYA GYDYHPEGCH RSCFQNGLID DCSCGDPRFP VPEGYRHCSA FNATARTCLE KNIGSVGDFH HITQKMDKCV CKQSCEEIIH EVTFSCSKWP SGATDLGDCD GMTESECEQY YRLNAAMIEV FYEQLNYELL QESEAYGLVN LIADFGGHLG LWLGFSVITV MEVCVLLVDM ISLFFKSRHE EKLLRQSTKR KDVPEDKRQI TVGSGRKSDA FVSI //