ID A0A4R7UEC7_9GAMM Unreviewed; 800 AA. AC A0A4R7UEC7; DT 31-JUL-2019, integrated into UniProtKB/TrEMBL. DT 31-JUL-2019, sequence version 1. DT 14-DEC-2022, entry version 7. DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438}; DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438}; GN ORFNames=N440_3836 {ECO:0000313|EMBL:TDV26194.1}; OS Stenotrophomonas sp. CC22-02. OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; OC Xanthomonadaceae; Stenotrophomonas. OX NCBI_TaxID=1378087 {ECO:0000313|EMBL:TDV26194.1, ECO:0000313|Proteomes:UP000294916}; RN [1] {ECO:0000313|EMBL:TDV26194.1, ECO:0000313|Proteomes:UP000294916} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CC22-02 {ECO:0000313|EMBL:TDV26194.1, RC ECO:0000313|Proteomes:UP000294916}; RA Currie C.; RT "Bioprospecting for lignincellulytic microbes and enzymes from natural, RT highly-evolved plant biomass-degrading systems."; RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L- CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085}; CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:TDV26194.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; SOCO01000002; TDV26194.1; -; Genomic_DNA. DR AlphaFoldDB; A0A4R7UEC7; -. DR Proteomes; UP000294916; Unassembled WGS sequence. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro. DR CDD; cd00082; HisKA; 1. DR Gene3D; 3.30.565.10; -; 1. DR InterPro; IPR011006; CheY-like_superfamily. DR InterPro; IPR003594; HATPase_C. DR InterPro; IPR036890; HATPase_C_sf. DR InterPro; IPR005467; His_kinase_dom. DR InterPro; IPR003661; HisK_dim/P. DR InterPro; IPR036097; HisK_dim/P_sf. DR InterPro; IPR035965; PAS-like_dom_sf. DR InterPro; IPR013655; PAS_fold_3. DR InterPro; IPR004358; Sig_transdc_His_kin-like_C. DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver. DR Pfam; PF02518; HATPase_c; 1. DR Pfam; PF00512; HisKA; 1. DR Pfam; PF08447; PAS_3; 1. DR Pfam; PF00072; Response_reg; 1. DR PRINTS; PR00344; BCTRLSENSOR. DR SMART; SM00387; HATPase_c; 1. DR SMART; SM00388; HisKA; 1. DR SMART; SM00448; REC; 1. DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1. DR SUPFAM; SSF52172; CheY-like; 1. DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1. DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1. DR PROSITE; PS50109; HIS_KIN; 1. DR PROSITE; PS50110; RESPONSE_REGULATORY; 1. PE 4: Predicted; KW Kinase {ECO:0000313|EMBL:TDV26194.1}; Membrane {ECO:0000256|SAM:Phobius}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE- KW ProRule:PRU00169}; Signal {ECO:0000256|SAM:SignalP}; KW Transferase {ECO:0000313|EMBL:TDV26194.1}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT SIGNAL 1..23 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 24..800 FT /note="histidine kinase" FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5020241477" FT TRANSMEM 252..275 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 434..653 FT /note="Histidine kinase" FT /evidence="ECO:0000259|PROSITE:PS50109" FT DOMAIN 675..793 FT /note="Response regulatory" FT /evidence="ECO:0000259|PROSITE:PS50110" FT MOD_RES 724 FT /note="4-aspartylphosphate" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169" SQ SEQUENCE 800 AA; 85761 MW; 0FB5CFA40DC103C0 CRC64; MNVVGFPAAA VMACLLLPAT TSARCGSPLR IAWPSDRTPL SAGVQGQANG PDADYLALLG AQRPLQPQPL LAAAVAEGRV PDGIQALLGW PRSQLPPGWV ASAPYLQLPQ VIVQRRDAPP VMGVGALRGR TVASPDPGPL AAMLAEQAPG AQLLPPAPLD DALSLLGTGL VDAVIANLGE VEAALRRYHG DPLVVAAPAG FDDALVLATV PACAAVIDEF EQVVSGLSGA QREAIRAAWL PATPRSQSSP SALHWLVPAS LILLALALVY AFGYWRVHRE SERRRVAAQR LREVTSNLPA VVFQARRSAA GHYSIPQIAG DVQALFGISV ETALIDPQRL LAAVHPDDCE RLTEAVDAAA LAREPIDVLF RTLSPLGWRW VHSHGRPLPR ADGIVEWSGY WMDVSEVQSR TRALAHARRE AEQVALAKTH FLATMSHQIR TPMSTLLGML ERLADSELEV HQRQVLATVG DAARMLRQIL DDVLHSQRLQ PAPLQLRPTD LAALLRAVQQ LLMPVAASRG LHLTLELDPA LQAGLLADGL RLRQILFNLA GNALKFTEHG GVELQVQVLQ RLQGGQRLRL QVSDSGVGIS PERQQAVFAA YTQAETSTTR RFGGSGLGLA ICRELASSMG AELQLRSRPG EGTTVWMELE LASCELPAVM SPLPAAAMLP LPPARVLVAE DHPTNLHLLE QRLRGLGLHV QACTDGRKAL EAWHAGAFDV VITDCHMPDV DGFALARAIR ADTCPARARV PIIALTASVL DRTREACRDA GIEHFLAKPV ETHSLNALLA RLLAPDSTRQ //