ID A0A4Q4X7Z3_9PEZI Unreviewed; 1866 AA. AC A0A4Q4X7Z3; DT 31-JUL-2019, integrated into UniProtKB/TrEMBL. DT 31-JUL-2019, sequence version 1. DT 13-NOV-2019, entry version 4. DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075}; GN ORFNames=DL771_011976 {ECO:0000313|EMBL:RYP56324.1}; OS Monosporascus sp. 5C6A. OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Xylariomycetidae; Xylariales; OC Xylariales incertae sedis; Monosporascus; unclassified Monosporascus. OX NCBI_TaxID=2211642 {ECO:0000313|EMBL:RYP56324.1, ECO:0000313|Proteomes:UP000292526}; RN [1] {ECO:0000313|EMBL:RYP56324.1, ECO:0000313|Proteomes:UP000292526} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=5C6A {ECO:0000313|EMBL:RYP56324.1, RC ECO:0000313|Proteomes:UP000292526}; RA Robinson A.J., Natvig D.O.; RT "Complete Genomes of Monosporascus."; RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Fungal fatty CC acid synthetase subunit alpha family. CC {ECO:0000256|PIRNR:PIRNR000454}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:RYP56324.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QJOB01000783; RYP56324.1; -; Genomic_DNA. DR Proteomes; UP000292526; Unassembled WGS sequence. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW. DR GO; GO:0042759; P:long-chain fatty acid biosynthetic process; IEA:UniProtKB-UniRule. DR Gene3D; 3.40.47.10; -; 3. DR Gene3D; 3.90.470.20; -; 1. DR HAMAP; MF_00101; AcpS; 1. DR InterPro; IPR008278; 4-PPantetheinyl_Trfase_dom. DR InterPro; IPR037143; 4-PPantetheinyl_Trfase_dom_sf. DR InterPro; IPR002582; ACPS. DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase. DR InterPro; IPR040899; Fas_alpha_ACP. DR InterPro; IPR026025; FAS_alpha_yeast. DR InterPro; IPR041550; FASI_helical. DR InterPro; IPR018201; Ketoacyl_synth_AS. DR InterPro; IPR014031; Ketoacyl_synth_C. DR InterPro; IPR014030; Ketoacyl_synth_N. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR InterPro; IPR009081; PP-bd_ACP. DR InterPro; IPR004568; Ppantetheine-prot_Trfase_dom. DR InterPro; IPR016039; Thiolase-like. DR Pfam; PF01648; ACPS; 1. DR Pfam; PF18325; Fas_alpha_ACP; 1. DR Pfam; PF18314; FAS_I_H; 1. DR Pfam; PF00109; ketoacyl-synt; 1. DR Pfam; PF02801; Ketoacyl-synt_C; 1. DR PIRSF; PIRSF000454; FAS_yeast_alpha; 1. DR SUPFAM; SSF51735; SSF51735; 1. DR SUPFAM; SSF52151; SSF52151; 1. DR SUPFAM; SSF53901; SSF53901; 2. DR SUPFAM; SSF56214; SSF56214; 1. DR TIGRFAMs; TIGR00556; pantethn_trn; 1. DR PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1. DR PROSITE; PS50075; CARRIER; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000292526}; KW Magnesium {ECO:0000256|PIRSR:PIRSR000454-3}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR000454-3}; KW Phosphopantetheine {ECO:0000256|PIRNR:PIRNR000454, KW ECO:0000256|PIRSR:PIRSR000454-4, ECO:0000256|PROSITE- KW ProRule:PRU00258}; KW Reference proteome {ECO:0000313|Proteomes:UP000292526}; KW Transferase {ECO:0000256|PIRNR:PIRNR000454, KW ECO:0000256|SAAS:SAAS01225069}. FT DOMAIN 143 218 Carrier. {ECO:0000259|PROSITE:PS50075}. FT REGION 96 136 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT ACT_SITE 1281 1281 For beta-ketoacyl synthase activity. FT {ECO:0000256|PIRSR:PIRSR000454-1}. FT METAL 1752 1752 Magnesium. {ECO:0000256|PIRSR: FT PIRSR000454-3}. FT METAL 1753 1753 Magnesium; via carbonyl oxygen. FT {ECO:0000256|PIRSR:PIRSR000454-3}. FT METAL 1754 1754 Magnesium. {ECO:0000256|PIRSR: FT PIRSR000454-3}. FT METAL 1852 1852 Magnesium. {ECO:0000256|PIRSR: FT PIRSR000454-3}. FT METAL 1853 1853 Magnesium; via carbonyl oxygen. FT {ECO:0000256|PIRSR:PIRSR000454-3}. FT MOD_RES 178 178 O-(pantetheine 4'-phosphoryl)serine. FT {ECO:0000256|PIRSR:PIRSR000454-4, FT ECO:0000256|PROSITE-ProRule:PRU00258}. SQ SEQUENCE 1866 AA; 203885 MW; 4A6AA1556C63A9FF CRC64; MRPEVEQELA HTLLVELLAY QFASPVRWIE TQDVLLAEQQ AERIVEIGPA DTLGVMAKRT IASKYEAFDA AKSLQRQILC SAKDGKEIYY EGDPIEEESE PAAAAQPGSS GTAPAPAPAA AAAPAAAPAP SAGPAAAVPD APIPAMDVVR ALIAQKLKKP FLEIPLSKAI KDLVGGKSTL QNEILGDLGK EFGSTPEKPE DTPLDELGGL MQATFNGQLG KTTQGLIARV ISSKMPGGFN ITTARKYLES RWGLGPGRQD GVLVFAITME PASRLGSEAD AKAFFDDVTQ KYASHAGVSL STAAAAGPAG GSGGAMMMDP EALEALTKDQ KVLYKNQLEL LARYLKIDLR AGEKAAQATQ QSQAVLQAQI DLWTAEHGDF YASGIEPSFS PLKARSYDSS WNWARQDVLS MYYDVLFGKL KVVDREIVSQ CIRIMSKSNP KLLEFMQYHI DNCPTERGET YRLAKELGEQ LIENCRDVLS VPPVYKDVNV PTGPHTTVDA RGNLAYEEVP RANCRKLEHY VQQMAEGGKI SEYGGRTKVQ NDLGRLVKLI KEQHKMSKTA KLEFKALYGN VLRSLAMNES QILNKDSGKA NGLVKKSSSL KGSSQASKGK METIPFLHLK RSTLHGWEYS KKLTGVYLDV LEAAARNGIS YEGKYALMTG AGAGSIGAEV LSGLISGGAK VIVTTSRFSP EVTQYYQAMY AKFGARGSQL VVVPFNGGSK QDVEALVNYI YDTKNGLGWD LDYIVPFAAI PEQGRQIDGI DSRSELAHRI MLTNVVRLLG AVKSQKDEHG YLTRPAQVIL PLSPNHGTFG NDGLYSESKL GLETLFNRWH SEDWANYLSI TGAVIGWTRG TGLMSGNNIV AEGVEAFGVR TFSQQEMAFN LLGLMSPDIA DICQNEPVFA DLNGGLQFIP NLNETMTRLR KDIMETSEIR RAVTKETAIE NKVVNGENSE ALYKKKVIAP RANIKFDFPT LPDWKTEIEP LNKSLEGMVD LERVVVVTGF AEVGPWGNAR TRWEMEAYGH FSLEGCVEMA WIMGLIKNHN GPIKGQPYSG WVDAKTGEPV DDKDIKQKYE SHILEHSGIR LVEPELFFGY NPEKKQLLQE VAIDEDLEPF EASKDLAQAY KREHGDKCEI FEIPESGEYI VRMKKGATLW IPKAIRFDRL VAGQIPTGWD AKRYGIEDDI ISQVDRSTLF VLVSVAEALV SAGITDPYEF YKYVHVSEVG NMIGAGMGGS NALHGMYVER KLDRPVQNDV LQETFINTAA AWVNMLLLSS SGPIKTPVGA CATAVESVDI GYDTIMEGKA RICIVGGYDE FSEEGSNEFA MMNATSNAID EFAHGRTPKE MSRPTTTTRN GFMESQGAGC QIIMTAKLAI EMGLPIYGIL ALTTTASDKI GRSVPAPGQG VLTTARENSS KFPSPLLDLN YRRRQIDIRK RQITSWKESE LEYLYEEVAA MKVQSPGFDE KAYTQERALH IEKEAARQET EAVRSLGNNF WKQDNSIAPL RGALATWGLT IDDLDVASFH GTSTKANDKN ESSVINKQLT HLGRKKGNAV LGIFQKYLTG HPKGAAGAWM MNGCLQVLNT GLVPGNRNAD NVDPVMEEFD LIVYPSRSIQ TDGVKAFSVT SFGFGQKGAQ AIGVHPKYLF AVLDQSTYAQ YAAKVTARQK KAYRFLHNGM INNSIFKAKN NSPYTDDQLR SVLLNPDART SDDKKTMAIT YAANFAKQTA EPQAAKTKKT KQVVESLAQT LRTGKNNKVG VDVEDISAIN IENATFIERN FTAHEIDYCR NAANPQSSFA GRWSAKEAVF KSLGVQSKGA GAALKEIEIL SNDVGAPIVS LHGDAETAAK KAGVKEISIS ISHSDDQAIA IAVATF //