ID A0A4P8F534_9POAL Unreviewed; 362 AA. AC A0A4P8F534; DT 31-JUL-2019, integrated into UniProtKB/TrEMBL. DT 31-JUL-2019, sequence version 1. DT 07-APR-2021, entry version 7. DE RecName: Full=NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic {ECO:0000256|HAMAP-Rule:MF_01350}; DE EC=7.1.1.- {ECO:0000256|HAMAP-Rule:MF_01350}; DE AltName: Full=NAD(P)H dehydrogenase subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350}; DE Short=NDH subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350}; DE AltName: Full=NADH-plastoquinone oxidoreductase subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350}; GN Name=ndhA {ECO:0000256|HAMAP-Rule:MF_01350, GN ECO:0000313|EMBL:QCO74613.1}; OS Aeluropus lagopoides. OG Plastid; Chloroplast {ECO:0000313|EMBL:QCO74613.1}. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade; OC Chloridoideae; Cynodonteae; Aeluropodinae; Aeluropus. OX NCBI_TaxID=293749 {ECO:0000313|EMBL:QCO74613.1}; RN [1] {ECO:0000313|EMBL:QCO74613.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=31037212; DOI=.1093/aobpla/plz017; RA Anderson B.M., Thiele K.R., Grierson P.F., Krauss S.L., Nevill P.G., RA Small I.D., Zhong X., Barrett M.D.; RT "Recent range expansion in Australian hummock grasses (Triodia) inferred RT using genotyping-by-sequencing."; RL AoB Plants 11:plz017-plz017(2019). RN [2] {ECO:0000313|EMBL:QCO74613.1} RP NUCLEOTIDE SEQUENCE. RA Barrett M., Zhong X., Small I.; RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN CC and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain CC and possibly in a chloroplast respiratory chain. The immediate electron CC acceptor for the enzyme in this species is believed to be CC plastoquinone. Couples the redox reaction to proton translocation, and CC thus conserves the redox energy in a proton gradient. CC {ECO:0000256|HAMAP-Rule:MF_01350}. CC -!- CATALYTIC ACTIVITY: CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n CC H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561, CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757, CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192; CC Evidence={ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000474}; CC -!- CATALYTIC ACTIVITY: CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n CC H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561, CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757, CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192; CC Evidence={ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000474}; CC -!- SUBUNIT: NDH is composed of at least 16 different subunits, 5 of which CC are encoded in the nucleus. {ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000474}. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU000471}; CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU000471}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. Plastid, chloroplast thylakoid CC membrane {ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000474}; Multi-pass membrane protein CC {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}. CC -!- SIMILARITY: Belongs to the complex I subunit 1 family. CC {ECO:0000256|ARBA:ARBA00010535, ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000471}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MK622397; QCO74613.1; -; Genomic_DNA. DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:UniProtKB-UniRule. DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-UniRule. DR GO; GO:0019684; P:photosynthesis, light reaction; IEA:UniProtKB-UniRule. DR HAMAP; MF_01350; NDH1_NuoH; 1. DR InterPro; IPR001694; NADH_UbQ_OxRdtase_su1/FPO. DR InterPro; IPR018086; NADH_UbQ_OxRdtase_su1_CS. DR PANTHER; PTHR11432; PTHR11432; 1. DR Pfam; PF00146; NADHdh; 1. DR PROSITE; PS00667; COMPLEX1_ND1_1; 1. DR PROSITE; PS00668; COMPLEX1_ND1_2; 1. PE 3: Inferred from homology; KW Chloroplast {ECO:0000256|RuleBase:RU000474, ECO:0000313|EMBL:QCO74613.1}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01350}; KW NAD {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000471}; KW NADP {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}; KW Plastid {ECO:0000256|RuleBase:RU000474, ECO:0000313|EMBL:QCO74613.1}; KW Plastoquinone {ECO:0000256|HAMAP-Rule:MF_01350, KW ECO:0000256|RuleBase:RU000474}; KW Quinone {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}; KW Thylakoid {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}; KW Translocase {ECO:0000256|HAMAP-Rule:MF_01350, KW ECO:0000256|RuleBase:RU000474}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP- KW Rule:MF_01350}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP- KW Rule:MF_01350}. FT TRANSMEM 23..49 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 94..115 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 121..147 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 254..276 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 296..323 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 335..353 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" SQ SEQUENCE 362 AA; 40330 MW; C9613582C6B439DA CRC64; MIIDRVEVET INSFSKSELL KEVYGLIWIL PILTLLLGIT IEVLVIVWLE REISASIQQR IGPEYAGPLG LLQAIADGTK LIFKEDILPS RGEIPLFSIG PSIAVISVLL SFLVIPFGYH FVLADLSIGV FLWIAISSVA PIGLLMAGYS SNNKYSFSGG LRAAAQSISY EIPLTFCVLA ISLLSNSSST VDIVEAQSKY GFFGWNLWRQ PIGFLVFLIS SLAECERLPF DLPEAEEELV AGYQTEYSGI KYGLFYLASY LNLLVSSLFV TVLYLGGWNF SIPYISFFGF FQMNKIVGIF EMIMGILITL TKAFLFLFIS ITIRWTLPRM RMDQLLNLGW KFLLPISLGN LLLTTSSQLV SL //