ID A0A4P6UM66_9BURK Unreviewed; 819 AA. AC A0A4P6UM66; DT 31-JUL-2019, integrated into UniProtKB/TrEMBL. DT 31-JUL-2019, sequence version 1. DT 07-APR-2021, entry version 6. DE RecName: Full=Histidine kinase {ECO:0000256|ARBA:ARBA00012438}; DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438}; GN ORFNames=DW355_14595 {ECO:0000313|EMBL:QBK05786.1}; OS Hylemonella gracilis. OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Comamonadaceae; Hylemonella. OX NCBI_TaxID=80880 {ECO:0000313|EMBL:QBK05786.1, ECO:0000313|Proteomes:UP000292939}; RN [1] {ECO:0000313|EMBL:QBK05786.1, ECO:0000313|Proteomes:UP000292939} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NS1 {ECO:0000313|EMBL:QBK05786.1, RC ECO:0000313|Proteomes:UP000292939}; RA Tyc O., Kulkarni P., Gawehns F., Hundscheid M., Zweers H., Garbeva P.; RT "Exploring interactions and the metabolic potential of the ultra-small soil RT bacteria Hylemonella gracilis."; RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L- CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP031395; QBK05786.1; -; Genomic_DNA. DR EnsemblBacteria; QBK05786; QBK05786; DW355_14595. DR Proteomes; UP000292939; Chromosome. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro. DR CDD; cd00082; HisKA; 1. DR Gene3D; 3.30.565.10; -; 1. DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2. DR InterPro; IPR011006; CheY-like_superfamily. DR InterPro; IPR003594; HATPase_C. DR InterPro; IPR036890; HATPase_C_sf. DR InterPro; IPR005467; His_kinase_dom. DR InterPro; IPR003661; HisK_dim/P. DR InterPro; IPR036097; HisK_dim/P_sf. DR InterPro; IPR004358; Sig_transdc_His_kin-like_C. DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver. DR Pfam; PF07696; 7TMR-DISMED2; 1. DR Pfam; PF02518; HATPase_c; 1. DR Pfam; PF00512; HisKA; 1. DR Pfam; PF00072; Response_reg; 1. DR PRINTS; PR00344; BCTRLSENSOR. DR SMART; SM00387; HATPase_c; 1. DR SMART; SM00388; HisKA; 1. DR SMART; SM00448; REC; 1. DR SUPFAM; SSF47384; SSF47384; 1. DR SUPFAM; SSF52172; SSF52172; 1. DR SUPFAM; SSF55874; SSF55874; 1. DR PROSITE; PS50109; HIS_KIN; 1. DR PROSITE; PS50110; RESPONSE_REGULATORY; 1. PE 4: Predicted; KW Membrane {ECO:0000256|SAM:Phobius}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE- KW ProRule:PRU00169}; Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT SIGNAL 1..35 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 36..819 FT /note="Histidine kinase" FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5020980765" FT TRANSMEM 200..220 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 225..249 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 255..275 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 287..306 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 312..329 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 336..355 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 454..673 FT /note="Histidine kinase" FT /evidence="ECO:0000259|PROSITE:PS50109" FT DOMAIN 697..811 FT /note="Response regulatory" FT /evidence="ECO:0000259|PROSITE:PS50110" FT MOD_RES 746 FT /note="4-aspartylphosphate" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169" SQ SEQUENCE 819 AA; 90776 MW; 8D30AC7DBAEA5212 CRC64; MRLGCRLWLT QLVGRMRVLR LCLLLTGLST PWAHATTIDA CADSQQLLGG KVEVHVDGTG RQTPEEIARL PASAFAPLDP QTLPRYSEAG VWLDMTLHNT QSQPCRRWLN LAKPSVEDQQ VHVLRVDGLW HSQRSGSAYA LRTWAVAQRQ PVFLLDLQPG ETTRVLARVS STSSILLVNP QLYSDAAWLQ TQQNTHIIDG LSQGIVLLVV AVGLTVGWIL RSGMLLALSV GALFNALFVC VVNGYLFYFP ALLPYTEACA AVTGTFAISG FLIYVRQLYG LSRLPRLWTH MIVALVGFYI LTRIVGWYAA PAMTSIGLWV IVSFVAVLLH GRRHQFMAWL GMHIMALQLL SQYVFHLDKA VPWAQHFPPA LELLSSLVWQ SSYVQNLSGT LNGAVWLAAT MVLEVLGSQR REQRAQAALE NQRRGELERL ESAVAQRTGQ LREALDARRN LLARISHDLR SPLAGIINIT QSAAALEAQT TRHIERSARR QMELIDELLE FARQDLKGPE IHAEPGYLYA LLHEMEQEGR LLAQRQQNRF ETEIPIDLPL VVRADFRHLR QVLLNLMGNA AKFTTQGEIR LQVEPLDGDE RETGNGRTRL RFSVCDTGQG IAESERDKVM QPFGRGANAR GVDGVGLGLT IVRQLLDGMG TELELASTPG QGSRFSFALD LELADESEVR DIFVESHAAE VEGRGRRILV ADDLPANRDQ LTDLLGGYGF EVSAAADGLE ALQMLREDDY DLLLTDQMMP RMDGWELLAQ ARASRPRLPV LLYSAAPPLP PLDWPADLGF DASLLKPATS GELLRQIDSL VRAAGPSAQ //