ID A0A4D6K4Y2_9VIRU Unreviewed; 350 AA. AC A0A4D6K4Y2; DT 03-JUL-2019, integrated into UniProtKB/TrEMBL. DT 03-JUL-2019, sequence version 1. DT 03-MAY-2023, entry version 10. DE RecName: Full=Replicase large subunit {ECO:0000256|ARBA:ARBA00013540}; DE Flags: Fragment; GN Name=RdRp {ECO:0000313|EMBL:QCD25041.1}; OS Tomato brown rugose fruit virus. OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes; OC Martellivirales; Virgaviridae; Tobamovirus. OX NCBI_TaxID=1761477 {ECO:0000313|EMBL:QCD25041.1}; RN [1] {ECO:0000313|EMBL:QCD25041.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TBRFV-BC {ECO:0000313|EMBL:QCD25041.1}; RA Camacho-Beltran E., Perez Villareal A., Rodriguez Negrete E.A., RA Mendez Lozano J.; RT "First report of Tomato Brown Rugose Fruit Virus infecting tomato crops in RT Baja California, Mexico."; RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MH891505; QCD25041.1; -; Genomic_RNA. DR GO; GO:0003723; F:RNA binding; IEA:InterPro. DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW. DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro. DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro. DR InterPro; IPR043502; DNA/RNA_pol_sf. DR InterPro; IPR001788; RNA-dep_RNA_pol_alsuvir. DR InterPro; IPR007094; RNA-dir_pol_PSvirus. DR Pfam; PF00978; RdRP_2; 1. DR SUPFAM; SSF56672; DNA/RNA polymerases; 1. DR PROSITE; PS50507; RDRP_SSRNA_POS; 1. PE 4: Predicted; KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695}; KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484, KW ECO:0000313|EMBL:QCD25041.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}; KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}. FT DOMAIN 182..295 FT /note="RdRp catalytic" FT /evidence="ECO:0000259|PROSITE:PS50507" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:QCD25041.1" FT NON_TER 350 FT /evidence="ECO:0000313|EMBL:QCD25041.1" SQ SEQUENCE 350 AA; 40538 MW; 17956BD96B8F7BC7 CRC64; MVRTAAEMPR QTGLLENLVA MIKRNFNSPE LSGIIDIENT ASLVVDKFFD SYLLKEKRKP NKNVSLFCRE SLNRWLEKQE QVTIGQLADF DFVDLPAVDQ YRHMIKAQPK QKLDTSIQSE YPALQTIVYH SKKINAIFGP LFSELTRQML ESIDSSKFLF FTRKTPAQIE DFFGDLDSHV PMDILELDIS KYDKSQNEFH CAVEYEIWRR LGLEDFLGEV WKQGHRKTTL KDYTAGIKTC LWYQRKSGDV TTFIGNTVII AACLASMLPM EKIIKGAFCG DDSLLYFPKG CEFPDIQHTA NLMWNFEAKL FRKQYGYFCG RYVIHHDRGC IVYYDPLKLI SKLGAKHIKD //