ID A0A484E5H7_BRELC Unreviewed; 366 AA. AC A0A484E5H7; DT 05-JUN-2019, integrated into UniProtKB/TrEMBL. DT 05-JUN-2019, sequence version 1. DT 12-OCT-2022, entry version 10. DE RecName: Full=HNHc domain-containing protein {ECO:0000256|Google:UnProtein}; GN ORFNames=CCR75_009540 {ECO:0000313|EMBL:TDH70095.1}; OS Bremia lactucae (Lettuce downy mildew). OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae; OC Bremia. OX NCBI_TaxID=4779 {ECO:0000313|EMBL:TDH70095.1, ECO:0000313|Proteomes:UP000294530}; RN [1] {ECO:0000313|EMBL:TDH70095.1, ECO:0000313|Proteomes:UP000294530} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SF5 {ECO:0000313|EMBL:TDH70095.1, RC ECO:0000313|Proteomes:UP000294530}; RA Fletcher K.; RT "Genomic signatures of somatic hybrid vigor due to heterokaryosis in the RT oomycete pathogen, Bremia lactucae."; RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:TDH70095.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; SHOA01000013; TDH70095.1; -; Genomic_DNA. DR VEuPathDB; FungiDB:CCR75_009540; -. DR Proteomes; UP000294530; Unassembled WGS sequence. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR InterPro; IPR045379; Crinkler_N. DR InterPro; IPR003615; HNH_nuc. DR Pfam; PF20147; Crinkler; 1. DR Pfam; PF13391; HNH_2; 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000294530}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..17 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 18..366 FT /note="HNHc domain-containing protein" FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5019861316" FT DOMAIN 2..116 FT /note="Crinkler" FT /evidence="ECO:0000259|Pfam:PF20147" FT DOMAIN 175..234 FT /note="HNHc" FT /evidence="ECO:0000259|Pfam:PF13391" SQ SEQUENCE 366 AA; 42217 MW; 6CF73A1F391DC7D4 CRC64; MVTLLCLIVG LAGNAFCVDI DDSKFIGHLK DKIKEKKFNT IKGEARTLQL FLAKTADDKW LSSCSEDVKK LKEGEKTSLI ETLTSEDKEL QEEHLLEDVL IGMERPSARQ IHVLVVLPEQ ENDIVKTAFM DLVQVMVPHM LMMAPTTRTT RNDFFKHKLC KFYKNYQRNG TWVRCMLLDV AFPKSLVIAS HLFRRSNKYV ADKLLKISNI NDTRNGIVLF KPLKYAFDHF HISFVRDNTG AFRLKLFDPT IRNTRLIDMV IDHSRNKKVL DETQVTELHE SISLTQEPCE FNVNTTFGDL DGSALAFIGV ERPYNRCLYL QASVARVLAL QNGWVEESYD FPDFWDDVDL DNKMDIFHRS LLEADI //