ID A0A484DTN6_BRELC Unreviewed; 618 AA. AC A0A484DTN6; DT 05-JUN-2019, integrated into UniProtKB/TrEMBL. DT 05-JUN-2019, sequence version 1. DT 31-JUL-2019, entry version 3. DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:TDH65809.1}; GN ORFNames=CCR75_004056 {ECO:0000313|EMBL:TDH65809.1}; OS Bremia lactucae (Lettuce downy mildew). OC Eukaryota; Stramenopiles; Oomycetes; Peronosporales; Peronosporaceae; OC Bremia. OX NCBI_TaxID=4779 {ECO:0000313|EMBL:TDH65809.1, ECO:0000313|Proteomes:UP000294530}; RN [1] {ECO:0000313|EMBL:TDH65809.1, ECO:0000313|Proteomes:UP000294530} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SF5 {ECO:0000313|EMBL:TDH65809.1, RC ECO:0000313|Proteomes:UP000294530}; RA Fletcher K.; RT "Genomic signatures of somatic hybrid vigor due to heterokaryosis in RT the oomycete pathogen, Bremia lactucae."; RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases. CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; CC Evidence={ECO:0000256|PIRSR:PIRSR000106-3}; CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; CC Evidence={ECO:0000256|PIRSR:PIRSR000106-3}; CC Note=Divalent metal cations. Prefers magnesium or manganese. CC {ECO:0000256|PIRSR:PIRSR000106-3}; CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:TDH65809.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; SHOA01000118; TDH65809.1; -; Genomic_DNA. DR Proteomes; UP000294530; Unassembled WGS sequence. DR Gene3D; 3.40.50.10380; -; 1. DR InterPro; IPR012301; Malic_N_dom. DR InterPro; IPR037062; Malic_N_dom_sf. DR InterPro; IPR012302; Malic_NAD-bd. DR InterPro; IPR001891; Malic_OxRdtase. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR Pfam; PF00390; malic; 1. DR Pfam; PF03949; Malic_M; 1. DR PIRSF; PIRSF000106; ME; 1. DR PRINTS; PR00072; MALOXRDTASE. DR SMART; SM01274; malic; 1. DR SMART; SM00919; Malic_M; 1. DR SUPFAM; SSF51735; SSF51735; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000294530}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR000106-3}; KW Reference proteome {ECO:0000313|Proteomes:UP000294530}. FT DOMAIN 141 321 malic. {ECO:0000259|SMART:SM01274}. FT DOMAIN 331 583 Malic_M. {ECO:0000259|SMART:SM00919}. FT ACT_SITE 164 164 Proton donor. {ECO:0000256|PIRSR: FT PIRSR000106-1}. FT ACT_SITE 235 235 Proton acceptor. {ECO:0000256|PIRSR: FT PIRSR000106-1}. FT METAL 306 306 Divalent metal cation. FT {ECO:0000256|PIRSR:PIRSR000106-3}. FT METAL 307 307 Divalent metal cation. FT {ECO:0000256|PIRSR:PIRSR000106-3}. FT METAL 330 330 Divalent metal cation. FT {ECO:0000256|PIRSR:PIRSR000106-3}. SQ SEQUENCE 618 AA; 68133 MW; A87F0EAD9E800773 CRC64; MLALQVRTQK RLLLNATTAS VALHKRFASA PVITEDHEEN EEALSVGEPS GFERDTLDTY LNSLQKYNPP IKTGLKGLNI IHDPLYNKGT GFPHVERDRL GLRGLVPPRR LSVEAQLSKL YDTFSQERDP LGKSRFLTDL HDRNETLFFR LLIKHMKEMA PIVYTPTVGV VCQKFGHLYR RPRGMFFSTR DRSQFGAMVY NWPCDDVEVI VVTDGSRILG LGDLGANGMG IPIGKLALYT AAGGIDPRKV LPVMLDTGTN NQTLLNDPYY LGVQQPRLTG EAFWSMVDEF MRAVRHRWPK VLVQFEDFSS EHAADVLNAY RLKQLCFNDD IQGTGATVLA GALSACERVK IPLKEQRIVI LGAGSAGLGV ASTLLQGMLR EGMTIPEARE RFYILDQYGL LGEARDSLNS GQQFFSRSDL ADKTNLVEVI KQAKPTMLMG LSAAAGAFTQ EAVEEMAKHA EQPIVFPLSN PTSVAECTAE QAYEWTTGKC VFASGSPFEP VTYNGTQYNI SQCNNMFIFP GVGLASSVIQ ATRVTDGMLY SAAKALSQCM TSDEIANGQV FPSVENIRDV SLKVATAVCE TALDEDVAGV RPKIRRGGTL EDFVASKMYF PAYHALVE //