ID A0A484BRB2_DRONA Unreviewed; 1257 AA. AC A0A484BRB2; DT 05-JUN-2019, integrated into UniProtKB/TrEMBL. DT 05-JUN-2019, sequence version 1. DT 14-DEC-2022, entry version 15. DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}; GN ORFNames=AWZ03_002122 {ECO:0000313|EMBL:TDG51327.1}; OS Drosophila navojoa (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila. OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG51327.1, ECO:0000313|Proteomes:UP000295192}; RN [1] {ECO:0000313|EMBL:TDG51327.1, ECO:0000313|Proteomes:UP000295192} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG51327.1}; RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG51327.1}; RX PubMed=30423125; DOI=.1093/jhered/esy059; RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.; RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in RT the mojavensis Cluster."; RL J. Hered. 110:118-123(2019). CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:TDG51327.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LSRL02000009; TDG51327.1; -; Genomic_DNA. DR RefSeq; XP_017956658.1; XM_018101169.1. DR AlphaFoldDB; A0A484BRB2; -. DR STRING; 7232.A0A484BRB2; -. DR GeneID; 108651447; -. DR KEGG; dnv:108651447; -. DR OMA; FSSCFEI; -. DR Proteomes; UP000295192; Unassembled WGS sequence. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro. DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom. DR InterPro; IPR008266; Tyr_kinase_AS. DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1. DR PRINTS; PR00109; TYRKINASE. DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141}; KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141}; KW Reference proteome {ECO:0000313|Proteomes:UP000295192}. FT DOMAIN 139..395 FT /note="Protein kinase" FT /evidence="ECO:0000259|PROSITE:PS50011" FT REGION 1..46 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 530..562 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 681..703 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 761..782 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 846..885 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 1225..1257 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 543..562 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 688..703 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 846..866 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1234..1257 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT BINDING 168 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141" SQ SEQUENCE 1257 AA; 135716 MW; 09B6F4586F3BB2D0 CRC64; MNLNQHSGPG PPESSTTTTT TTSSSSSSTS CSSNINNNTN NIHNKSCDQV DASPNLWRDS STSGMCSVSH RVGEPTAELS AGGLSNSVIN NTNWSTKSTS HDHPPPTSVM RTISSDRLVT GSSCRALRTA VSALYSVDDF VKEKIGSGFF SEVYRVTHRT TGQVMVLKMN QLRANRPNML REVQLLNKLS HANILSFMGV CVHEGQLHAL TEYINGGSLE QLLANKELPL SAAQKVRLAL GISRGMTYLH DAGIFHRDLT SKNVLVRHLA DGQYEAVVGD FGLAAKIPVK SGKTRLETVG SPYWVSPECL KGQWYDQTSD VFSFGIILCE IIARIEADPD LMPRTASFGL DYLAFVELCP MDTPPVFLRL AFYCCLYDPK SRPTFSDATK KLTLLLEKCE QESRCASPMS SLELINCSPI GSDIESAIPL ANTASSTVEN IFTAPAGVLT PRCQRDVDED GFRFPSTGIS CKSASAAMPG TPNWLADSAE YDDEHILKSR VRRATQKLEA EILLHRRSLS ENIIHFPLHT SPSDKARCHQ MQRQRSSTHS PTPPRQVGDP QTATVLLPTT TATTTTTKLS DSPLIIPLVP AVLTLRKVGE TMCLKDPQYK PTTTKDPNGV KPNPFTALAQ LRGVKKILGA NPKTYAAGVG DLFSSCFEMT APFFKELVAM QAKGVTAGAE LEPNASGAPP TASCTEPKSL PASPQLTRKY SAIELKLPQR SSNAASVAAS EASEAPAATA LPTPVLTDID DCDYCNSEGE DLDGGGNCAD AESSSDDSAV RPAAMPVARK YRANSLYTHP LFRGSSGTIM KYSNSELEVA TLLKTSNSAN TLTSLNLTTT DMISGNNQVE YGGNELSQSS LSEKDAASKS PPPEEIPATN PAPTDFELNG LKNSCDLLPT KRNLTRRDSI ESGFFSCFNE ESDAATTNTS YTRQLCGIGS LVVGSGSSSS CCYDQLKSLN LASNKLNDKL ASLCRCCYYA TPSSTSAMVA AAAVTPQQHH SDSPTASSSV LFIDNEATAI TGGGNTSSST ALDSTDELDA EIMAPPTHHR RYTCHHSLVG GDSQMTATTA GLINRLALDS EIHSLLQRSP FATNQLLYCK NRTSSIYTDS SDDISSDSLL WDDRSFTALP TTRSAQIAKI VEYFERKRQE SLPASMCNRN GNGTVAAAVA ASALGSNYLS YDSHRYSDFK RHLSPDSICF ELDKKPQQQR IMVCEGAVKS KLSIFDKKKQ QQQHQQHQQQ QQQQQQQQQS MGNGQGG //