ID A0A432GQJ8_9DELT Unreviewed; 336 AA. AC A0A432GQJ8; DT 08-MAY-2019, integrated into UniProtKB/TrEMBL. DT 08-MAY-2019, sequence version 1. DT 03-JUL-2019, entry version 3. DE RecName: Full=Glyceraldehyde-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361160}; DE EC=1.2.1.- {ECO:0000256|RuleBase:RU361160}; GN Name=gap {ECO:0000313|EMBL:RTZ85826.1}; GN ORFNames=DSY93_05285 {ECO:0000313|EMBL:RTZ90114.1}, DSY96_03995 GN {ECO:0000313|EMBL:RTZ85826.1}, DSY98_01625 GN {ECO:0000313|EMBL:RTZ82057.1}; OS SAR324 cluster bacterium. OC Bacteria; Proteobacteria; Deltaproteobacteria; SAR324 cluster. OX NCBI_TaxID=2024889 {ECO:0000313|EMBL:RTZ85826.1}; RN [1] {ECO:0000313|EMBL:RTZ85826.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=MAG 151 {ECO:0000313|EMBL:RTZ90114.1}, MAG 58 RC {ECO:0000313|EMBL:RTZ85826.1}, and MAG 63_2 RC {ECO:0000313|EMBL:RTZ82057.1}; RA Trembath-Reichert E., Huber J.A.; RT "Combined omics and stable isotope probing to characterize newly RT discovered Mariana Back-Arc vent microbial communities."; RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the glyceraldehyde-3-phosphate CC dehydrogenase family. {ECO:0000256|RuleBase:RU000397}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:RTZ85826.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QNZM01000062; RTZ82057.1; -; Genomic_DNA. DR EMBL; QNZK01000140; RTZ85826.1; -; Genomic_DNA. DR EMBL; QNZH01000148; RTZ90114.1; -; Genomic_DNA. DR GO; GO:0051287; F:NAD binding; IEA:InterPro. DR GO; GO:0050661; F:NADP binding; IEA:InterPro. DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro. DR GO; GO:0006006; P:glucose metabolic process; IEA:InterPro. DR InterPro; IPR020831; GlycerAld/Erythrose_P_DH. DR InterPro; IPR020830; GlycerAld_3-P_DH_AS. DR InterPro; IPR020829; GlycerAld_3-P_DH_cat. DR InterPro; IPR020828; GlycerAld_3-P_DH_NAD(P)-bd. DR InterPro; IPR006424; Glyceraldehyde-3-P_DH_1. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR PANTHER; PTHR10836; PTHR10836; 1. DR Pfam; PF02800; Gp_dh_C; 1. DR Pfam; PF00044; Gp_dh_N; 1. DR PIRSF; PIRSF000149; GAP_DH; 1. DR PRINTS; PR00078; G3PDHDRGNASE. DR SMART; SM00846; Gp_dh_N; 1. DR SUPFAM; SSF51735; SSF51735; 1. DR TIGRFAMs; TIGR01534; GAPDH-I; 1. DR PROSITE; PS00071; GAPDH; 1. PE 3: Inferred from homology; KW NAD {ECO:0000256|PIRSR:PIRSR000149-3}; KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000149-3}; KW Oxidoreductase {ECO:0000256|RuleBase:RU361160}. FT DOMAIN 3 153 Gp_dh_N. {ECO:0000259|SMART:SM00846}. FT NP_BIND 12 13 NAD. {ECO:0000256|PIRSR:PIRSR000149-3}. FT REGION 152 154 Glyceraldehyde 3-phosphate binding. FT {ECO:0000256|PIRSR:PIRSR000149-2}. FT REGION 212 213 Glyceraldehyde 3-phosphate binding. FT {ECO:0000256|PIRSR:PIRSR000149-2}. FT ACT_SITE 153 153 Nucleophile. {ECO:0000256|PIRSR: FT PIRSR000149-1}. FT BINDING 34 34 NAD. {ECO:0000256|PIRSR:PIRSR000149-3}. FT BINDING 78 78 NAD; via carbonyl oxygen. FT {ECO:0000256|PIRSR:PIRSR000149-3}. FT BINDING 120 120 NAD. {ECO:0000256|PIRSR:PIRSR000149-3}. FT BINDING 183 183 Glyceraldehyde 3-phosphate. FT {ECO:0000256|PIRSR:PIRSR000149-2}. FT BINDING 235 235 Glyceraldehyde 3-phosphate. FT {ECO:0000256|PIRSR:PIRSR000149-2}. FT BINDING 317 317 NAD. {ECO:0000256|PIRSR:PIRSR000149-3}. FT SITE 180 180 Activates thiol group during catalysis. FT {ECO:0000256|PIRSR:PIRSR000149-4}. SQ SEQUENCE 336 AA; 36093 MW; C1FA54E2ED5990A1 CRC64; MTIRIAINGF GRIGRMVVRA ANKNQNVEIV AINDLVPSEN LAYLLKYDST HGRFDGDVQA GQDCLVVDGK TIECLSERNP GDLPWNKMNI DYVIESTGLF TTSEKAEEHL KAGAKKVVIS APAKSAEIKT LVMGVNNETY DPGTDNIVSN ASCTTNCLAP IVKVVLDNYG IEEGLMTTVH SVTAAQPTVD GPSKKDWRGG RGGPQNIIPA STGAAKAVAL CIPEIAGKLT GMSFRVPTPN VSVVDLTVKL SKSTSYEEIN SSMKAASEGK LKGILGFTDE DVVSSDFIGS TYSSIYDAGA GIGLNDRFFK LVSWYDNEMG YSTRLIDLIE YMEGQN //