ID A0A430QFP9_SCHBO Unreviewed; 206 AA. AC A0A430QFP9; DT 08-MAY-2019, integrated into UniProtKB/TrEMBL. DT 08-MAY-2019, sequence version 1. DT 22-FEB-2023, entry version 15. DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:RTG86509.1}; GN ORFNames=DC041_0012195 {ECO:0000313|EMBL:RTG86509.1}; OS Schistosoma bovis (Blood fluke). OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda; OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma. OX NCBI_TaxID=6184 {ECO:0000313|EMBL:RTG86509.1, ECO:0000313|Proteomes:UP000290809}; RN [1] {ECO:0000313|EMBL:RTG86509.1, ECO:0000313|Proteomes:UP000290809} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=TAN1997 {ECO:0000313|EMBL:RTG86509.1, RC ECO:0000313|Proteomes:UP000290809}; RA Oey H., Zakrzewski M., Gobert G., Gravermann K., Stoye J., Jones M., RA Mcmanus D., Krause L.; RT "Genome sequence of the bovine parasite Schistosoma bovis Tanzania."; RL PLoS Pathog. 0:0-0(2019). CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004477}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the INSIG family. CC {ECO:0000256|ARBA:ARBA00007475}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:RTG86509.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QMKO01001795; RTG86509.1; -; Genomic_DNA. DR AlphaFoldDB; A0A430QFP9; -. DR STRING; 6184.A0A430QFP9; -. DR Proteomes; UP000290809; Unassembled WGS sequence. DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. DR GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW. DR InterPro; IPR025929; INSIG_fam. DR PANTHER; PTHR15301:SF12; INSILUN INDUCED PROTEIN; 1. DR PANTHER; PTHR15301; INSULIN-INDUCED GENE 1; 1. DR Pfam; PF07281; INSIG; 1. PE 3: Inferred from homology; KW Cholesterol metabolism {ECO:0000256|ARBA:ARBA00022548}; KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824}; KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023221}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000290809}; KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221}; KW Sterol metabolism {ECO:0000256|ARBA:ARBA00023166}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 12..31 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 115..133 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 139..159 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 171..193 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 206 AA; 23087 MW; 218BB94DBD9DCB47 CRC64; MVLLLQTTKF PVLVYRGLLL FFLGICFCWV SEALHNIKGE FTASKISFYT ESAAKFWISF CCGVASVTVG LLSPCVDSKL GAFDAYNKEW SSVLRCAALF FGFSHATARI DFATYSQLSL TAIGLSIALW WVFDRSLVGF VFGMAVALLA TFIFQSFVWK QLYRYSHPMM AAWLPCLFFS GGVVIVLVGR QLAKPDVMEL MQRKVK //