ID A0A417D9F9_9FIRM Unreviewed; 245 AA. AC A0A417D9F9; DT 08-MAY-2019, integrated into UniProtKB/TrEMBL. DT 08-MAY-2019, sequence version 1. DT 03-MAY-2023, entry version 12. DE SubName: Full=SDR family NAD(P)-dependent oxidoreductase {ECO:0000313|EMBL:RHT04674.1}; GN ORFNames=DW884_20220 {ECO:0000313|EMBL:RHT04674.1}; OS Ruminococcus sp. AM40-10AC. OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; OC Ruminococcus. OX NCBI_TaxID=2293212 {ECO:0000313|EMBL:RHT04674.1, ECO:0000313|Proteomes:UP000285366}; RN [1] {ECO:0000313|EMBL:RHT04674.1, ECO:0000313|Proteomes:UP000285366} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AM40-10AC {ECO:0000313|EMBL:RHT04674.1, RC ECO:0000313|Proteomes:UP000285366}; RA Zou Y., Xue W., Luo G.; RT "A genome reference for cultivated species of the human gut microbiota."; RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR) CC family. {ECO:0000256|RuleBase:RU000363}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:RHT04674.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QUIR01000050; RHT04674.1; -; Genomic_DNA. DR AlphaFoldDB; A0A417D9F9; -. DR Proteomes; UP000285366; Unassembled WGS sequence. DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. DR CDD; cd05233; SDR_c; 1. DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR InterPro; IPR002347; SDR_fam. DR PANTHER; PTHR43639; OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870); 1. DR PANTHER; PTHR43639:SF1; OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870); 1. DR Pfam; PF00106; adh_short; 1. DR PRINTS; PR00081; GDHRDH. DR PRINTS; PR00080; SDRFAMILY. DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1. PE 3: Inferred from homology; KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023221}; KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221}. SQ SEQUENCE 245 AA; 27567 MW; A46924225620DA72 CRC64; MSKVTVITGG TSGIGRGIVE KILANSAEDD LIFATYAHNA YKANEFWDNL KPEDQEKLII LKADMSSYDD MMNFVGEVKE KAGHVDWLIS NAGISTYDKF QDYTFEEWNK IVNTNLSVPV FMVKEFMSVM TEGGRVLFMG SYAGQQAYSS SLVYGVTKAA IHFLTKSLVK EFEPKGITVN AIAPGFIQTP WHENRTPESY ERINRKIALH RFGEIKDVAD MAYSILTNNY MNGSIVDIHG GYDYF //