ID A0A417A5D8_9FIRM Unreviewed; 347 AA. AC A0A417A5D8; DT 08-MAY-2019, integrated into UniProtKB/TrEMBL. DT 08-MAY-2019, sequence version 1. DT 03-MAY-2023, entry version 12. DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:RHS61821.1}; GN ORFNames=DW958_14210 {ECO:0000313|EMBL:RHS61821.1}; OS Ruminococcus sp. AM46-18. OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; OC Ruminococcus. OX NCBI_TaxID=2293220 {ECO:0000313|EMBL:RHS61821.1, ECO:0000313|Proteomes:UP000284979}; RN [1] {ECO:0000313|EMBL:RHS61821.1, ECO:0000313|Proteomes:UP000284979} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AM46-18 {ECO:0000313|EMBL:RHS61821.1, RC ECO:0000313|Proteomes:UP000284979}; RA Zou Y., Xue W., Luo G.; RT "A genome reference for cultivated species of the human gut microbiota."; RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:RHS61821.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QUIC01000034; RHS61821.1; -; Genomic_DNA. DR RefSeq; WP_055152220.1; NZ_QUIC01000034.1. DR AlphaFoldDB; A0A417A5D8; -. DR Proteomes; UP000284979; Unassembled WGS sequence. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro. DR CDD; cd01392; HTH_LacI; 1. DR CDD; cd01544; PBP1_GalR; 1. DR Gene3D; 3.40.50.2300; -; 2. DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1. DR InterPro; IPR000843; HTH_LacI. DR InterPro; IPR046335; LacI/GalR-like_sensor. DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf. DR InterPro; IPR028082; Peripla_BP_I. DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1. DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1. DR Pfam; PF00356; LacI; 1. DR Pfam; PF13377; Peripla_BP_3; 1. DR PRINTS; PR00036; HTHLACI. DR SMART; SM00354; HTH_LACI; 1. DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1. DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1. DR PROSITE; PS00356; HTH_LACI_1; 1. DR PROSITE; PS50932; HTH_LACI_2; 1. PE 4: Predicted; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}. FT DOMAIN 1..57 FT /note="HTH lacI-type" FT /evidence="ECO:0000259|PROSITE:PS50932" SQ SEQUENCE 347 AA; 38747 MW; 9AFA2487BDBF42F7 CRC64; MTLREIAAEA GVSISTVSRV INQNTKSPVS KEVQDRIWEI AKRTNYVPRH SKKNTSDSSD LSSTEQLHSI ACLFARVPDG ASDYFFSTLA KNIEQEAFRH NYILKYTFSA FDIDDPFTLR LIASNNIDGI AVLGRCDKEL LKFLKKHFQY VVYSGLNNLD AKYDQIICDG TQISYDVVTR LIEQGHTKIA YIGETQNENR YAGYCSALAD AGISVNQKYI ANIVHSTEEG YKGVHHLLNN GCDATAFFCA DDITAIGAMK AIKEHGLHIP EDVSVASIDD IDTAQYLTPP LTTTHIPLDE MGQMAAKVLI DRIEGGHTKH LKILFPYDIM ERKSTAALRK IHDNPQK //