ID A0A411D397_TSWVS Unreviewed; 2874 AA. AC A0A411D397; DT 08-MAY-2019, integrated into UniProtKB/TrEMBL. DT 08-MAY-2019, sequence version 1. DT 14-DEC-2022, entry version 9. DE RecName: Full=RNA-directed RNA polymerase L {ECO:0000256|ARBA:ARBA00018602}; DE EC=2.7.7.48 {ECO:0000256|ARBA:ARBA00012494}; DE AltName: Full=Large structural protein {ECO:0000256|ARBA:ARBA00030285}; DE AltName: Full=Replicase {ECO:0000256|ARBA:ARBA00031012}; DE AltName: Full=Transcriptase {ECO:0000256|ARBA:ARBA00030436}; GN Name=RdRp {ECO:0000313|EMBL:QAY29290.1}; OS Tomato spotted wilt virus (strain SA-05) (TSWV) (Groundnut ringspot virus). OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; OC Ellioviricetes; Bunyavirales; Tospoviridae; Orthotospovirus. OX NCBI_TaxID=12675 {ECO:0000313|EMBL:QAY29290.1}; OH NCBI_TaxID=133901; Frankliniella occidentalis (Western flower thrips) (Euthrips occidentalis). OH NCBI_TaxID=163899; Scirtothrips dorsalis (Chilli thrips). OH NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum). OH NCBI_TaxID=161014; Thrips tabaci. RN [1] {ECO:0000313|EMBL:QAY29290.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=LEM {ECO:0000313|EMBL:QAY29290.1}; RA De Marchi B.R., Bello V.H., Watanabe L.F.M., da Silva F.B., Mueller C., RA Pavan M.A., Krause-Sakate R.; RT "Characterization and complete genome sequence of groundnut ringspot RT orthotospovirus in soybean in Brazil."; RL J. Plant Pathol. 0:0-0(2018). RN [2] {ECO:0000313|EMBL:QAY29290.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=LEM {ECO:0000313|EMBL:QAY29290.1}; RA Rossitto De Marchi B., Bello V.H., Maranho Watanabe L.F., RA Barreto da Silva F., Pavan M.A., Krause-Sakate R.; RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MH686228; QAY29290.1; -; Genomic_RNA. DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW. DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro. DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro. DR InterPro; IPR007099; RNA-dir_pol_NSvirus. DR InterPro; IPR015841; RNA-dir_pol_tospovirus. DR InterPro; IPR007322; RNA_pol_bunyavir. DR Pfam; PF04196; Bunya_RdRp; 1. DR PIRSF; PIRSF036872; L_TospoV; 1. DR PROSITE; PS50525; RDRP_SSRNA_NEG_SEG; 1. PE 4: Predicted; KW Nucleotidyltransferase {ECO:0000313|EMBL:QAY29290.1}; KW RNA-directed RNA polymerase {ECO:0000313|EMBL:QAY29290.1}; KW Transferase {ECO:0000313|EMBL:QAY29290.1}. FT DOMAIN 1351..1533 FT /note="RdRp catalytic" FT /evidence="ECO:0000259|PROSITE:PS50525" SQ SEQUENCE 2874 AA; 330435 MW; 230BC0FC68A3DCA4 CRC64; MNIQKIRKLI ENGTTLLLSI EDCVGSNHDL ALDLHKRNSD EIPEDVIINN NAKNYETMRE LIVKISTDGE GLNTGIATVD VKKLNELVSL FEQKYLETEL SRHDLFGELV SRHLRIKPKQ RNEVEIELAL RDYLEELNKK QCVNSLSNDE FERINREYVA TNATPDNYVI YKESKNSELC LMIYDWKISV DAKTETKTME KYYKNIWKSF KDIKVNGKPF LEDHPVFITI VILKPMGGMP ITVTSSRVLG KFEDSPSALH GERSKLAKNA KLLNIYHVGM IVGTTPTIVR NYYANTQKLK SEVRGILGDD FGSKDVFFSH WASKYKDRNP TEIAYSEDIE RIIESLTTEE ITKDEIVHFL FGNFCYHIET MNDQHIADKF KGYQDACLNL KVVPKIDLSD LKDHLIQTQD VWESLYGRHL DKILQRIKKK KGKEREIPDI TTAFNQNAVE YEEKYPNCFT NDLSETKTNF SMTWSPSFEK VELNSSIDYN NAIIKKFRDS FQTTSRINYN SPYSSVHNQT NKARDVTNLV KLCLTELSCD TTKFSKQELE DEIDINTGSI KVERTKKSQE WCKHGSCLTR NKNEFCMKDT GKENKAVYFK GLAVMNIGMS SKKRILKKEE IKERISKGLE YDTSVRQTDP NDDYTSVDMA SLTHMKKLIR HDNEESLSWC EKIKDSLFVL HNGDIREEGK IASVYNNYAK NPECLYTQDS VLKTEMETCK KINKLCNDLA IYHYSEDMMQ FAKGLMVADR YMTKESFKIL TTANTSMILL AFKGDGMNTG GSGVPYIALH IVDEDMSEQF NICYTKEIYS YFRSGNNYIY VMRPQRLNQV RLLSLFKSPS KVPVCFAQFS KKASELEKWL KNKDTEKVNV FSMTVTVKQI LINIVFSSVM IGTVTKLSRM GIFDFMRYAG FLPLSDYSNI KEYIRDKFDP DITNVADIYF VNGIKKLLFR MEDLNLSTNA KPVVVDHEND VIGGITNLNI KCPITGSTLL TLEDLYNNVY LAIYMMPKSL HNHVHNLTSL LNVPAEWELK FRKELGFTIY EDIYPKKDMF DDKDLFSING LLNVKALSDY YIENVENVGL MRSEIENKED FLSPCYKITT LKSSKKCSQS SIINTDDIIE CLQTVKVKDV GNWKGNTLAI IKGLIRTYNE EKNRLIEFLE DNCVNSLYLL EKLKEIISSG SVTVGKSMTS KFIRNNHPLT VETYLKTKLY YRNNVTVLKS KKVSEELYDL VKQFHNMMEI DIDSVMNLGK GLEGKKHTFL QMLEFVISKA KNVTGSVDFL VSVFEKMQRT KTDREIYLMS MKVKMMLYFI EHTFKHVAQS DPSEAISISG DNKIRALSTL SLDTITSYND ILNKSSKKSR LAFLSADQSK WSASDLTYKY ILAILLNPVL TTGEASLMVE CLLMYVKLKK VCIPTDIFLN LKKSQSTFGQ NETAIGLLTK GLTTNTYPVS MNWLQGNLNY LSSVYHSCAM KAYHKTLECY KGCEFQTRWI VHSDDNATSL IANGEVDKML LDFSSSSLPE MLFRSIEAHF KSFCITLNPK KSYASSSEVE FISERIVNGA IIPLYCRHLA NCCTESSHIS YFDDLMSLSI HVTMLLRKGC PNEVIPFAYG AVQVQALSIY SMLPGEVNDS IRIFQKLGVS LMPNEIPTNM GGWLTAPIEP LSILGPSSND QIIYYNVIRD FLNKKSLEEV KNSVSTLGYL QKRFKELEEK HKKGTLEIKD KKMIFLINLF EKASVSEDSD VLTIGMKFQT MLTQIIKLPQ FINENALNKM SSYKDFSKLY PNLKKNEDLY KSTKNIKFNE DSLLEEDELY EKVASSAEME SVHNIMIQNP ETILIAPLND RDFLLSQLFM YTSPSKRNQL SNQSTEKLAL DRVLRSKART FVDIDSHVKM TYEENMEKKV LEMQKFDPGS YCSFKTCINL VIKDVNFSML TPILDAAYPC ESRKRDNYNF RWFQTEKWIP VVEGSPGLVV MHAIYGSNYI ENLGLKNIPL TDDSINVLTS TFGTNLLMDD VKSFVSGSSS FETESFINAN NCQRLVKACN YMITAQNRLL AINTCFSRKS FPFYSKFNLG RGFISNTLAL LSTIYSKEES YHFVSTANYK LDKTIRTVLN AQQDMNLEKI LDTAVYISDK LQSLFPTITR EDISLILQNI CLDSKPIWES LEEKMRKINN STGSGFTVSN VILSHNSELN TIQKQVVWLW NMGLCSNRTL DFVIRYIRRS DVRYVKTEEQ DELGNYISGT IYKIGIMTRS CYVQLIASDH DVAVTLRTPF EILNERDYLY DTYRESIEKL LQKFMFDKIN IIKSKQPQIV FLEPGEACLR MTTDNKMIVK VNATPKQIRL ENVKLVIKIK YENVNSDVWD IIESQKSLVL REPEIGECFS DMYKTVDSEA EAIKVIKQGL MNSLTFIETF GNLSKQINGI EDETVRETMH DFLMNIKETC LEGLENCKSI EEYDNFLAEN GFDDTVELFE DLLKTQDSFE NEYSPLFSEI VDRAKQYTRD LEGFKEILLM LKYSLINDAS GFKSYRATGA HAVELMAKKH IEIGEFNLLG MIQLIKACET CHNNDSILNL ASLRNVLSRT YATFGRRINL NHELDLQNNL MEKSYDFKTL VLPDIKLSDM SREILKDNGF IISGENLKID KSEEEFEGLA NFNMLRLDEE EMYEGLIKEM KIKRKKKGFL FPANTLLLSE LIKFLIGGIK GTSFDIETLL RNSFRPDIYS TDRLGRLSSS VPALKVYATV YMEYKNTSCP LNEIADSLEG FLKLTKSKAK EQFLDGRVKK ALIQLRDEQS RSKKLEIYRN IADFLSRHPL CLSEKTLYGR YTYHDINDYI MQTREIILSK INELDDYVEI DDDDFLLSYL KGEEDAFDED EESD //