ID A0A3S8YQC0_9GAMM Unreviewed; 532 AA. AC A0A3S8YQC0; DT 08-MAY-2019, integrated into UniProtKB/TrEMBL. DT 08-MAY-2019, sequence version 1. DT 03-JUL-2019, entry version 3. DE SubName: Full=Isocitrate lyase {ECO:0000313|EMBL:AZM95221.1}; DE EC=4.1.3.1 {ECO:0000313|EMBL:AZM95221.1}; GN ORFNames=EI420_05715 {ECO:0000313|EMBL:AZM95221.1}; OS Halomonas venusta. OC Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales; OC Halomonadaceae; Halomonas. OX NCBI_TaxID=44935 {ECO:0000313|EMBL:AZM95221.1, ECO:0000313|Proteomes:UP000275808}; RN [1] {ECO:0000313|EMBL:AZM95221.1, ECO:0000313|Proteomes:UP000275808} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MA-ZP17-13 {ECO:0000313|EMBL:AZM95221.1, RC ECO:0000313|Proteomes:UP000275808}; RA Li G.; RT "Halomonas venusta MA-ZP17-13."; RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases. CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; CC Evidence={ECO:0000256|PIRSR:PIRSR001362-3}; CC Note=Can also use Mn(2+) ion. {ECO:0000256|PIRSR:PIRSR001362-3}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP034367; AZM95221.1; -; Genomic_DNA. DR Proteomes; UP000275808; Chromosome. DR GO; GO:0004451; F:isocitrate lyase activity; IEA:UniProtKB-EC. DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro. DR CDD; cd00377; ICL_PEPM; 1. DR Gene3D; 3.20.20.60; -; 1. DR InterPro; IPR039556; ICL/PEPM. DR InterPro; IPR006254; Isocitrate_lyase. DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom. DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf. DR PANTHER; PTHR21631; PTHR21631; 1. DR Pfam; PF00463; ICL; 3. DR PIRSF; PIRSF001362; Isocit_lyase; 3. DR SUPFAM; SSF51621; SSF51621; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000275808}; KW Lyase {ECO:0000313|EMBL:AZM95221.1}; KW Magnesium {ECO:0000256|PIRSR:PIRSR001362-3}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR001362-3}. FT ACT_SITE 222 222 Proton acceptor. {ECO:0000256|PIRSR: FT PIRSR001362-1}. FT METAL 184 184 Magnesium. {ECO:0000256|PIRSR: FT PIRSR001362-3}. SQ SEQUENCE 532 AA; 59103 MW; 4CE56DA38A1ED81D CRC64; MSGLLDDIKA MAQLREAQGG KWEAIKPEYA ARMRAQNRFH TGLDIARYTA KIMRDDMAAY DADTSKYTQS LGCWHGFIGQ QKLISIKKHF GTTKRSYLYL SGWMVAALRS EFGPLPDQSM HEKTSVADLI EELYTFLKQA DAWELNHLFR ALDDAKEAGD SAKEQELISK IDNYETHIVP IIADIDAGFG NAEATYLLAK KFIQAGACCI QLENQVSDEK QCGHQDGKVT VPHEDFLAKI NAVRYAFLEL GIEDGVIVAR TDSLGAGLTQ KIAVTNEPGD LGDQYNSFLD GDVIENASDI NNGDVVIKQN GQLVKPKRLA SGLYQFKPGT GEDRVVLDCI TSLQNGADLL WIETEKPHVG QIASMVNRIR AVVPDAKLVY NNSPSFNWTL NFRQQVFDAW EKEGKDVSAY QRDKLMGVEY DNTELGQLAD EWTRNFQRDG AREAGIFHHL ITLPTYHTAA LSTDNLAKGY FGDEGMLAYV AGVQRQEIRQ GIATVKHQDM AGSNIGDDHK EFFHGDAALK AGGKDNTMNQ FG //