ID   A0A3S3SCJ4_9ACAR        Unreviewed;       579 AA.
AC   A0A3S3SCJ4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Metabotropic glutamate receptor 4-like protein {ECO:0000313|EMBL:RWS13506.1};
DE   Flags: Fragment;
GN   ORFNames=B4U79_07864 {ECO:0000313|EMBL:RWS13506.1};
OS   Dinothrombium tinctorium.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC   Trombidioidea; Trombidiidae; Dinothrombium.
OX   NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS13506.1, ECO:0000313|Proteomes:UP000285301};
RN   [1] {ECO:0000313|EMBL:RWS13506.1, ECO:0000313|Proteomes:UP000285301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS13506.1};
RA   Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA   Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT   "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT   transferred genes associated with secondary metabolism.";
RL   Gigascience 0:0-0(2018).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWS13506.1}.
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DR   EMBL; NCKU01000968; RWS13506.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S3SCJ4; -.
DR   STRING; 1965070.A0A3S3SCJ4; -.
DR   Proteomes; UP000285301; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   CDD; cd15045; 7tmC_mGluRs; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR017979; GPCR_3_CS.
DR   InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24060:SF134; MANGETOUT, ISOFORM G; 1.
DR   PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00593; MTABOTROPICR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:RWS13506.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        280..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        319..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        393..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        441..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        474..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        509..531
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          281..546
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:RWS13506.1"
FT   NON_TER         579
FT                   /evidence="ECO:0000313|EMBL:RWS13506.1"
SQ   SEQUENCE   579 AA;  66189 MW;  FB30FBA21993E542 CRC64;
     SDGWSARNLV SDGNELEVEG TISIQPKANP VNGFDDYFLQ LTPKNNFRNP WFIEYWEAYF
     KCKWPNSQAT PFNQFYKRNC NGNERMSYEN GYEPEKQLQF VSDAVLAFGY AFKAMHKELC
     NGERGLCNQM LPIDGTLLLK YLKKVHFVGL SGDRFQFTKN GDGPVRYNLI HFKQIEPGVF
     QWINVGTYEG ERLNLDLNKV QFHYSSDEIP VSVCSLPCNK GQAKKYIEGE NCCWHCFDCT
     KYQILIGETR CSDCPNGFLP DEEKLNCIQI PEEYVKADSL IAIFAIGFSS IGILFTLYVI
     YVFLRYIDTP VVRASGRELS FVLLIGLIMC FSLTFILLLK PSDIVCGIQQ LSIGISFALI
     YSAILTQSNR IYRIFTSGKK TAKRPNFISP KSQLIICFTL VLIQLIFLLL WFAFSPPKAI
     NLYLKREDNQ LICSSNVTDS YFIAFIYPIL LIIICTVYAI LTRKIPEAFN ESKHIGFTMY
     TTCIIWLAFV PIYFTTKTNI TLNLTTMSIA INFSATVTLI CLFTPKIYII LLHPERNVRQ
     SLMPFTKYGS LRKQCSSVPT NSTFKTELVV QSNGKRTIV
//