ID A0A3S2TK83_CHISP Unreviewed; 797 AA. AC A0A3S2TK83; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 19-JAN-2022, entry version 14. DE RecName: Full=F-spondin {ECO:0000256|ARBA:ARBA00018652}; DE AltName: Full=Spondin-1 {ECO:0000256|ARBA:ARBA00019594}; DE Flags: Fragment; GN ORFNames=evm_006967 {ECO:0000313|EMBL:RVE48406.1}; OS Chilo suppressalis (Asiatic rice borer moth). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Pyraloidea; OC Crambidae; Crambinae; Chilo. OX NCBI_TaxID=168631 {ECO:0000313|EMBL:RVE48406.1, ECO:0000313|Proteomes:UP000283053}; RN [1] {ECO:0000313|EMBL:RVE48406.1, ECO:0000313|Proteomes:UP000283053} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=HZU2018 {ECO:0000313|EMBL:RVE48406.1}; RC TISSUE=Whole body {ECO:0000313|EMBL:RVE48406.1}; RA Lin Y.; RT "Chilo suppressalis genome."; RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. CC -!- SIMILARITY: Belongs to the insect defense protein family. CC {ECO:0000256|ARBA:ARBA00008501}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:RVE48406.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; RSAL01000084; RVE48406.1; -; Genomic_DNA. DR STRING; 168631.A0A3S2TK83; -. DR Proteomes; UP000283053; Unassembled WGS sequence. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW. DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW. DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW. DR CDD; cd00109; KU; 1. DR Gene3D; 2.20.100.10; -; 3. DR Gene3D; 2.60.40.2130; -; 1. DR Gene3D; 2.60.40.4060; -; 1. DR Gene3D; 4.10.410.10; -; 1. DR InterPro; IPR002223; Kunitz_BPTI. DR InterPro; IPR036880; Kunitz_BPTI_sf. DR InterPro; IPR020901; Prtase_inh_Kunz-CS. DR InterPro; IPR002861; Reeler_dom. DR InterPro; IPR042307; Reeler_sf. DR InterPro; IPR009465; Spondin_N. DR InterPro; IPR038678; Spondin_N_sf. DR InterPro; IPR000884; TSP1_rpt. DR InterPro; IPR036383; TSP1_rpt_sf. DR Pfam; PF00014; Kunitz_BPTI; 1. DR Pfam; PF02014; Reeler; 1. DR Pfam; PF06468; Spond_N; 1. DR Pfam; PF00090; TSP_1; 2. DR PRINTS; PR00759; BASICPTASE. DR SMART; SM00131; KU; 1. DR SMART; SM00209; TSP1; 3. DR SUPFAM; SSF57362; SSF57362; 1. DR SUPFAM; SSF82895; SSF82895; 2. DR PROSITE; PS00280; BPTI_KUNITZ_1; 1. DR PROSITE; PS50279; BPTI_KUNITZ_2; 1. DR PROSITE; PS51019; REELIN; 1. DR PROSITE; PS51020; SPONDIN; 1. DR PROSITE; PS50092; TSP1; 3. PE 3: Inferred from homology; KW Antibiotic {ECO:0000256|ARBA:ARBA00023022}; KW Antimicrobial {ECO:0000256|ARBA:ARBA00022529}; KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889}; KW Immunity {ECO:0000256|ARBA:ARBA00022859}; KW Innate immunity {ECO:0000256|ARBA:ARBA00022588}; KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690}; KW Reference proteome {ECO:0000313|Proteomes:UP000283053}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}; KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900}; KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}. FT SIGNAL 1..17 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 18..797 FT /note="F-spondin" FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5018552384" FT DOMAIN 6..184 FT /note="Reelin" FT /evidence="ECO:0000259|PROSITE:PS51019" FT DOMAIN 185..379 FT /note="Spondin" FT /evidence="ECO:0000259|PROSITE:PS51020" FT DOMAIN 700..750 FT /note="BPTI/Kunitz inhibitor" FT /evidence="ECO:0000259|PROSITE:PS50279" FT REGION 775..797 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 797 FT /evidence="ECO:0000313|EMBL:RVE48406.1" SQ SEQUENCE 797 AA; 86798 MW; 0C763CF9EF87B1F7 CRC64; MLSIVILCVT SARLVSATAT TAQSPTCERA PAHAQPADAF YRLGIAGEPD LYLPGELYTV SLQGVDSGQG PTPFVGFTIW AEKDEESVKI DVVNSSAINQ SLGAFQSYDA QTKPHDFCMP AVDNATGHPK TDIQIIWSAP LRTSEACLRL CARAAPVGGG NGTVLARKIC AAPVAPASFA RQPPIIEPCC ACDEAKYEVT FEGLWSRNTH PRDFPPESAQ AHFGDVIGAS HTAQYRVWQE GRVASAGLRR LAEDGTTTAL EKELKSESDH IRTIIKARGI SWQQVAGFGT PNTFAVFRVD ARNHLVSLAS KLSPSPDWIV GVSALELCNA NCTWSHSATL PLYPYDAGTN SGITYMSRRQ PTLPPAPVRA LRPDWPKDPR SPFFSANGEM RPFARLRLTR LQLFEKNCDA AKSGAEAGVQ QAGDTGAGGA GAGGGGGGAC ATYAWGAWSA CSVSCGEGRA SRQRHYVWPL RAHAEACRVP LTDYTTCHGP RQHCRAPSDF EPPAASSTGP CALSAWSAWS PCEGCGVRAR TRHYLAPRAH KRCHLGYRAR AITSQAMPCE NGPCEKPAKY VNATNHDWFF VDQPSWPCKV TPWGDWSPCS SRCGRGRRLR TRLYLVQDAR AQPEMSRRLL QQWNKRFAEL QKLDFPSENL TTSKEGNDPE IEKLVQEQID KCQFTLSLQE ALCDGDDNLC VDTEKTQEVC KLSMVVGHCR GYEERWFYDM SRSTCEPFGF TGCGGNGNNF RTREQCHSLC GNLTASNTTS NASDNASVVQ SDVAVKKLKP TPPVEDNEVL QNDDPAQ //