ID A0A3S2P2X3_ORYJA Unreviewed; 1015 AA. AC A0A3S2P2X3; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 05-JUN-2019, entry version 3. DE RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; DE Short=PARP {ECO:0000256|RuleBase:RU362114}; DE EC=2.4.2.- {ECO:0000256|RuleBase:RU362114}; GN ORFNames=OJAV_G00229600 {ECO:0000313|EMBL:RVE55796.1}; OS Oryzias javanicus (Javanese ricefish) (Aplocheilus javanicus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; OC Oryziinae; Oryzias. OX NCBI_TaxID=123683 {ECO:0000313|EMBL:RVE55796.1}; RN [1] {ECO:0000313|EMBL:RVE55796.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=RS831 {ECO:0000313|EMBL:RVE55796.1}; RC TISSUE=Whole body {ECO:0000313|EMBL:RVE55796.1}; RA Lopez-Roques C., Donnadieu C., Bouchez O., Klopp C., Cabau C., RA Zahm M.; RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:RVE55796.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=RS831 {ECO:0000313|EMBL:RVE55796.1}; RC TISSUE=Whole body {ECO:0000313|EMBL:RVE55796.1}; RA Herpin A., Takehana Y., Naruse K., Ansai S., Kawaguchi M.; RT "A chromosome length genome reference of the Java medaka (oryzias RT javanicus)."; RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:RVE55796.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CM012460; RVE55796.1; -; Genomic_DNA. DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-UniRule. DR CDD; cd00027; BRCT; 1. DR Gene3D; 1.20.142.10; -; 1. DR Gene3D; 2.20.140.10; -; 1. DR Gene3D; 2.20.25.630; -; 1. DR Gene3D; 3.30.1740.10; -; 2. DR Gene3D; 3.40.50.10190; -; 1. DR InterPro; IPR001357; BRCT_dom. DR InterPro; IPR036420; BRCT_dom_sf. DR InterPro; IPR012982; PADR1. DR InterPro; IPR038650; PADR1_dom_sf. DR InterPro; IPR008288; PARP. DR InterPro; IPR012317; Poly(ADP-ribose)pol_cat_dom. DR InterPro; IPR004102; Poly(ADP-ribose)pol_reg_dom. DR InterPro; IPR036616; Poly(ADP-ribose)pol_reg_dom_sf. DR InterPro; IPR036930; WGR_dom_sf. DR InterPro; IPR008893; WGR_domain. DR InterPro; IPR001510; Znf_PARP. DR InterPro; IPR036957; Znf_PARP_sf. DR Pfam; PF00533; BRCT; 1. DR Pfam; PF08063; PADR1; 1. DR Pfam; PF00644; PARP; 1. DR Pfam; PF02877; PARP_reg; 1. DR Pfam; PF05406; WGR; 1. DR Pfam; PF00645; zf-PARP; 2. DR PIRSF; PIRSF000489; NAD_ADPRT; 1. DR SMART; SM00292; BRCT; 1. DR SMART; SM01335; PADR1; 1. DR SMART; SM00773; WGR; 1. DR SMART; SM01336; zf-PARP; 2. DR SUPFAM; SSF142921; SSF142921; 1. DR SUPFAM; SSF47587; SSF47587; 1. DR SUPFAM; SSF52113; SSF52113; 1. DR PROSITE; PS50172; BRCT; 1. DR PROSITE; PS51060; PARP_ALPHA_HD; 1. DR PROSITE; PS51059; PARP_CATALYTIC; 1. DR PROSITE; PS00347; PARP_ZN_FINGER_1; 1. DR PROSITE; PS50064; PARP_ZN_FINGER_2; 2. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Glycosyltransferase {ECO:0000256|RuleBase:RU362114}; KW NAD {ECO:0000256|RuleBase:RU362114}; KW Transferase {ECO:0000256|RuleBase:RU362114}. FT DOMAIN 10 92 PARP-type. {ECO:0000259|PROSITE:PS50064}. FT DOMAIN 114 204 PARP-type. {ECO:0000259|PROSITE:PS50064}. FT DOMAIN 388 464 BRCT. {ECO:0000259|PROSITE:PS50172}. FT DOMAIN 663 780 PARP alpha-helical. {ECO:0000259|PROSITE: FT PS51060}. FT DOMAIN 789 1015 PARP catalytic. {ECO:0000259|PROSITE: FT PS51059}. FT REGION 199 225 Disordered. {ECO:0000256|MobiDB-lite: FT A0A3S2P2X3}. FT REGION 357 393 Disordered. {ECO:0000256|MobiDB-lite: FT A0A3S2P2X3}. FT REGION 495 527 Disordered. {ECO:0000256|MobiDB-lite: FT A0A3S2P2X3}. FT COILED 401 421 {ECO:0000256|SAM:Coils}. FT COMPBIAS 509 523 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A3S2P2X3}. SQ SEQUENCE 1015 AA; 112866 MW; 6F252885537EE33E CRC64; MADSQNDKLF RAEYAKSGQA SCKKCKEKIA KESLRMAIVV QSPMFDGKVP HWHHFSCFWQ RASVQSTADV GGFSDLRWAD QEAVKKAIES GGVAGTGKGN SGSAAKGEKT LNDFAVEYAK SNRSTCKGCQ QKIEKDQIRV SKKVVDPEKP QLGLIDRWYH TACFVSSREE LAFKPNYSAA QLKGFNALRA EDKEELKKRL PAVKTEGKRP GDELDGVSKK LKQEEEEENK KLVENLKNQS QLIWGIKDKL RKHCSTNDMK ELLIANAQDV PSGESNVVDR VADGMAFGAL EACKECQGQL VFKGDAYYCT GDISAWTKCV FKTTTPPRKD WIIPKEFHEV PFLKKFKFKR QDRVYPKEAP TQTVTTAKGE PLASGSGALK EPLPEGAPSD KPLTGMKLLA VGKLSKNKEE LKTEVEEMGG KITGTANKAS LCLSTKKEVE KMGKKMEEIR DAGVRVVSED FLRDIKSSGK ALQELVSLHA ISTWGAEVKV EPQAPAAASK SGALAAKSTG RVKEEEGGNK SKKMKLTVKG GAAVDPDSGL ENSAHVLEQS GKMYSATLGL VDIVRGTNSY YKLQLLEDDL HKRYWVFRSW GRVGTTIGGN KLDKFHDKNS ALDNFLSVYK EKTGNEWGSS NFIKYPTKFY PLEIDYGQDE EAVKRLTASA GTKSKLAKPV QELIKMIFDV ESMKKAMVEF EIDLQKMPLG KLSKRQIQSA YALLTEVQQA VSDCVPEAQI LDLSNRFYTL IPHDFGMKKP PLLNSLDYIQ AKVEMLDNLL DIEVAYSLLR GGAQDNEHDP IDINYEKLKT KIEVVDKSSQ EAEVITQYVK NTHAATHNTY TLEVQEIFKI GREGERQRFR PFEELHNRQL LWHGSRTTNY AGIMSQGLRI APPEAPVTGY MFGKGVYFAD MVSKSANYCH TSQSDPVGLL LLAEVALGNM HELKKASHIT KLPKGKHSVK GLGRTAPDPN ATVTLDGVQV PLGKGVQTNI DDTSLLYNEY IVYDVAQINL KYLLKIKFNY QTSLW //