ID   A0A3R7X0E6_9PROT        Unreviewed;       225 AA.
AC   A0A3R7X0E6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   05-JUN-2019, entry version 3.
DE   RecName: Full=6-phosphogluconolactonase {ECO:0000256|RuleBase:RU365095};
DE            Short=6PGL {ECO:0000256|RuleBase:RU365095};
DE            EC=3.1.1.31 {ECO:0000256|RuleBase:RU365095};
GN   Name=pgl {ECO:0000256|RuleBase:RU365095, ECO:0000313|EMBL:RPH00392.1};
GN   ORFNames=CBD13_003265 {ECO:0000313|EMBL:RPH00392.1};
OS   Candidatus Pelagibacter sp. TMED153.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Pelagibacterales;
OC   Pelagibacteraceae; Candidatus Pelagibacter.
OX   NCBI_TaxID=1986803 {ECO:0000313|EMBL:RPH00392.1};
RN   [1] {ECO:0000313|EMBL:RPH00392.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=TMED153 {ECO:0000313|EMBL:RPH00392.1};
RX   PubMed=28713657; DOI=10.7717/peerj.3558;
RA   Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT   "290 metagenome-assembled genomes from the Mediterranean Sea: a
RT   resource for marine microbiology.";
RL   PeerJ 5:e3558-e3558(2017).
RN   [2] {ECO:0000313|EMBL:RPH00392.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=TMED153 {ECO:0000313|EMBL:RPH00392.1};
RA   Graham E.D., Tully B.J.;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Hydrolysis of 6-phosphogluconolactone to 6-
CC       phosphogluconate. {ECO:0000256|RuleBase:RU365095}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-
CC         gluconate + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57955, ChEBI:CHEBI:58759;
CC         EC=3.1.1.31; Evidence={ECO:0000256|RuleBase:RU365095};
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage):
CC       step 2/3. {ECO:0000256|RuleBase:RU365095}.
CC   -!- SIMILARITY: Belongs to the glucosamine/galactosamine-6-phosphate
CC       isomerase family. 6-phosphogluconolactonase subfamily.
CC       {ECO:0000256|RuleBase:RU365095}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:RPH00392.1}.
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DR   EMBL; NHHC02000047; RPH00392.1; -; Genomic_DNA.
DR   UniPathway; UPA00115; UER00409.
DR   GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR   CDD; cd01400; 6PGL; 1.
DR   InterPro; IPR005900; 6-phosphogluconolactonase_DevB.
DR   InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR039104; PGLS.
DR   PANTHER; PTHR11054; PTHR11054; 1.
DR   Pfam; PF01182; Glucosamine_iso; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   TIGRFAMs; TIGR01198; pgl; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU365095,
KW   ECO:0000313|EMBL:RPH00392.1}.
FT   DOMAIN       13    219       Glucosamine_iso. {ECO:0000259|Pfam:
FT                                PF01182}.
SQ   SEQUENCE   225 AA;  26625 MW;  748CF36E8C0033A1 CRC64;
     MTKFNKIIRK KTEKQLIVEF IRLFKSYIVK KEKLNQKFSF VLTGGSSPKN LYKSLSKSKI
     NWKNIYLFWG DERFVSKRST NSNFRLVKKN LLDKIDISKK NIFYIDTKKI DSYTSAKNYE
     NKIKRFFKNK KVSFDLILLG MGSDGHIASL FPDNLDLKTN KITSPVLRKD FQRITLNLNV
     INKAKKIFLW LNTKTKSNTY RKLKNNKKLP VNYINKDKTN LFLIN
//