ID A0A3R5V1F3_LACCU Unreviewed; 597 AA. AC A0A3R5V1F3; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 10-FEB-2021, entry version 8. DE SubName: Full=Cadmium-translocating P-type ATPase {ECO:0000313|EMBL:QAR35601.1}; DE EC=3.6.3.3 {ECO:0000313|EMBL:QAR35601.1}; GN Name=cadA {ECO:0000313|EMBL:QAR35601.1}; GN ORFNames=EQK21_05850 {ECO:0000313|EMBL:QAR35601.1}; OS Lactobacillus curvatus. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; OC Latilactobacillus. OX NCBI_TaxID=28038 {ECO:0000313|EMBL:QAR35601.1, ECO:0000313|Proteomes:UP000286835}; RN [1] {ECO:0000313|EMBL:QAR35601.1, ECO:0000313|Proteomes:UP000286835} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SRCM103465 {ECO:0000313|EMBL:QAR35601.1, RC ECO:0000313|Proteomes:UP000286835}; RA Kong H.-J., Jeong S.-Y., Jeong D.-Y.; RT "Genome sequence of Lactobacillus curvatus SRCM103465."; RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362081}. CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) CC family. Type IB subfamily. {ECO:0000256|ARBA:ARBA00006024, CC ECO:0000256|RuleBase:RU362081}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP035110; QAR35601.1; -; Genomic_DNA. DR Proteomes; UP000286835; Chromosome. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0008551; F:cadmium transmembrane transporter activity, phosphorylative mechanism; IEA:UniProtKB-EC. DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR Gene3D; 3.40.1110.10; -; 1. DR Gene3D; 3.40.50.1000; -; 1. DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N. DR InterPro; IPR018303; ATPase_P-typ_P_site. DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf. DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf. DR InterPro; IPR036412; HAD-like_sf. DR InterPro; IPR023214; HAD_sf. DR InterPro; IPR027256; P-typ_ATPase_IB. DR InterPro; IPR001757; P_typ_ATPase. DR PRINTS; PR00120; HATPASE. DR SUPFAM; SSF56784; SSF56784; 1. DR SUPFAM; SSF81653; SSF81653; 1. DR SUPFAM; SSF81665; SSF81665; 1. DR TIGRFAMs; TIGR01525; ATPase-IB_hvy; 1. DR TIGRFAMs; TIGR01494; ATPase_P-type; 1. DR PROSITE; PS00154; ATPASE_E1_E2; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|RuleBase:RU362081}; KW Hydrolase {ECO:0000313|EMBL:QAR35601.1}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081}; KW Metal-binding {ECO:0000256|RuleBase:RU362081}; KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081}; KW Translocase {ECO:0000256|ARBA:ARBA00022967}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, KW ECO:0000256|RuleBase:RU362081}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|RuleBase:RU362081}. FT TRANSMEM 6..25 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362081" FT TRANSMEM 32..50 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362081" FT TRANSMEM 227..246 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362081" FT TRANSMEM 252..273 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362081" FT TRANSMEM 551..578 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362081" SQ SEQUENCE 597 AA; 63283 MW; 20CB4EE6729BB2C9 CRC64; MKHTIKFALT ISVGVIALCL AFLLHEPLWA QILVSLAGSL VALSMFIEMI KTLKSGQYGV DLLAITAIIA TLAVGEYWAA LMVLVMLTGG DSLEDYAAHK AGRELKTLLD NSPQTAHRLV NDAVEDVSVD KLQVGDQVII KPGELVPVDG HIIAGSALFD ESSLTGESRP VEKALNDELM SGSVNGDTSV TMQVDQLAIN SQYQAIVRLV ETSAAQPAHF VRLADRYAVP FTLVAYVIAG VAWWLSKDPV RFAEVLVVAS PCPLILAAPI ALISGMSRAS RNGIIVKAGT TIEKLASAKS AAFDKTGTIT NGQLTVDQVV PVIGIAPTEL LQLAASAEQE SSHILARSLV KAAQVEQLQP IETLKEATGA GVVATLSSGQ MVRVGKHQFV TPDAQQPLQE QTTVYVAINE QYAGYITFID HLRPEAPATM QTLHQLGITR LMMLTGDQAT TAHQIAEQVG IDDVHAGCLP VDKIHLIEQV PQDQRPLIMV GDGVNDAPSL ASADVGIAMG AHGATAASES ADVVILKDDL GRVSRAVQIA RDTMRVARQA VLIGIAICIG LMLIASTGIV PALVGALFQE VVDTVSILYA LRARTDR //