ID A0A3Q8WHR6_9GAMM Unreviewed; 201 AA. AC A0A3Q8WHR6; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 27-MAR-2024, entry version 13. DE RecName: Full=Cysteine/O-acetylserine efflux protein {ECO:0000256|ARBA:ARBA00039172}; GN ORFNames=EI420_16795 {ECO:0000313|EMBL:AZM97215.1}; OS Halomonas venusta. OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales; OC Halomonadaceae; Halomonas. OX NCBI_TaxID=44935 {ECO:0000313|EMBL:AZM97215.1, ECO:0000313|Proteomes:UP000275808}; RN [1] {ECO:0000313|EMBL:AZM97215.1, ECO:0000313|Proteomes:UP000275808} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MA-ZP17-13 {ECO:0000313|EMBL:AZM97215.1, RC ECO:0000313|Proteomes:UP000275808}; RA Li G.; RT "Halomonas venusta MA-ZP17-13."; RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Exporter of O-acetylserine (OAS) and cysteine. CC {ECO:0000256|ARBA:ARBA00037717}. CC -!- CATALYTIC ACTIVITY: CC Reaction=L-cysteine(in) = L-cysteine(out); Xref=Rhea:RHEA:29655, CC ChEBI:CHEBI:35235; Evidence={ECO:0000256|ARBA:ARBA00036494}; CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:29656; CC Evidence={ECO:0000256|ARBA:ARBA00036494}; CC -!- CATALYTIC ACTIVITY: CC Reaction=O-acetyl-L-serine(in) = O-acetyl-L-serine(out); CC Xref=Rhea:RHEA:29659, ChEBI:CHEBI:58340; CC Evidence={ECO:0000256|ARBA:ARBA00036992}; CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:29660; CC Evidence={ECO:0000256|ARBA:ARBA00036992}; CC -!- SIMILARITY: Belongs to the Rht family. {ECO:0000256|ARBA:ARBA00007928}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP034367; AZM97215.1; -; Genomic_DNA. DR AlphaFoldDB; A0A3Q8WHR6; -. DR KEGG; hvn:EI420_16795; -. DR Proteomes; UP000275808; Chromosome. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0006865; P:amino acid transport; IEA:InterPro. DR InterPro; IPR001123; LeuE-type. DR PANTHER; PTHR30086; ARGININE EXPORTER PROTEIN ARGO; 1. DR PANTHER; PTHR30086:SF23; CYSTEINE_O-ACETYLSERINE EFFLUX PROTEIN; 1. DR Pfam; PF01810; LysE; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 43..67 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 79..95 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 115..136 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 143..167 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 179..200 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 201 AA; 21796 MW; 38B351D50E95F7EF CRC64; MNNEWLLLGP AALYMMSMTL TPGPNNIMLT ASGANFGFRR TMPHMWGILG GCFLLFSGIA LGLGVLFERF PMVQTTLRWL GSAYLLYLAW KIATAPPPNL NGTQHGVPLT FFQAAMFQFA NPKAWVMGLA LMAGFLPENG QPVVNALVLA GFAELVALPC IALWAAFGSA IGQWIKSDQA WRAFNITMGL LTAACVVLIL R //