ID A0A3Q7ZUA1_MAKNI Unreviewed; 380 AA. AC A0A3Q7ZUA1; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 05-JUN-2019, entry version 3. DE RecName: Full=Cytochrome b {ECO:0000256|RuleBase:RU362117}; GN Name=CYTB {ECO:0000313|EMBL:AKP99642.1}; OS Makaira nigricans (Atlantic blue marlin). OG Mitochondrion {ECO:0000313|EMBL:AKP99642.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Carangaria; Istiophoriformes; Makaira. OX NCBI_TaxID=13604 {ECO:0000313|EMBL:AKP99642.1}; RN [1] {ECO:0000313|EMBL:AKP99642.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=EP_48 {ECO:0000313|EMBL:AKP99642.1}; RA Chen H., Sun C.L., Yeh S.Z., Shao K.T.; RT "Genetic structure and phylogeography of blue marlin, Makaira RT nigricans, in the Pacific and eastern Indian oceans."; RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase CC complex (complex III or cytochrome b-c1 complex) that is part of CC the mitochondrial respiratory chain. The b-c1 complex mediates CC electron transfer from ubiquinol to cytochrome c. Contributes to CC the generation of a proton gradient across the mitochondrial CC membrane that is then used for ATP synthesis. CC {ECO:0000256|RuleBase:RU362117}. CC -!- COFACTOR: CC Name=heme; Xref=ChEBI:CHEBI:30413; CC Evidence={ECO:0000256|RuleBase:RU362117}; CC Note=Binds 2 heme groups non-covalently. CC {ECO:0000256|RuleBase:RU362117}; CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane CC {ECO:0000256|RuleBase:RU362117}. CC -!- SIMILARITY: Belongs to the cytochrome b family. CC {ECO:0000256|RuleBase:RU362117}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KP185000; AKP99642.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule. DR GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW. DR CDD; cd00290; cytochrome_b_C; 1. DR CDD; cd00284; Cytochrome_b_N; 1. DR Gene3D; 1.20.810.10; -; 1. DR InterPro; IPR005798; Cyt_b/b6_C. DR InterPro; IPR036150; Cyt_b/b6_C_sf. DR InterPro; IPR005797; Cyt_b/b6_N. DR InterPro; IPR027387; Cytb/b6-like_sf. DR InterPro; IPR030689; Cytochrome_b. DR InterPro; IPR016174; Di-haem_cyt_TM. DR Pfam; PF00032; Cytochrom_B_C; 1. DR Pfam; PF00033; Cytochrome_B; 1. DR PIRSF; PIRSF038885; COB; 1. DR SUPFAM; SSF81342; SSF81342; 1. DR SUPFAM; SSF81648; SSF81648; 1. DR PROSITE; PS51003; CYTB_CTER; 1. DR PROSITE; PS51002; CYTB_NTER; 1. PE 3: Inferred from homology; KW Electron transport {ECO:0000256|RuleBase:RU362117}; KW Heme {ECO:0000256|RuleBase:RU362117}; KW Iron {ECO:0000256|RuleBase:RU362117}; KW Membrane {ECO:0000256|RuleBase:RU362117}; KW Metal-binding {ECO:0000256|RuleBase:RU362117}; KW Mitochondrion {ECO:0000256|RuleBase:RU362117, KW ECO:0000313|EMBL:AKP99642.1}; KW Respiratory chain {ECO:0000256|RuleBase:RU362117}; KW Transmembrane {ECO:0000256|RuleBase:RU362117}; KW Transmembrane helix {ECO:0000256|RuleBase:RU362117}; KW Transport {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 29 52 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 87 107 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 113 133 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 145 166 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 178 200 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 229 250 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 288 308 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 320 341 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 347 372 Helical. {ECO:0000256|RuleBase:RU362117}. FT DOMAIN 1 209 CYTB_NTER. {ECO:0000259|PROSITE:PS51002}. FT DOMAIN 210 380 CYTB_CTER. {ECO:0000259|PROSITE:PS51003}. SQ SEQUENCE 380 AA; 42385 MW; 71C31C37B4866886 CRC64; MANLRKTHPL LKIANDALVD LPAPSNISVW WNFGSLLGLC LATQLLTGLF LAMHYTSDIA TAFTSVAHIC RDVNYGWLIR NMHANGASFF FICIYLHIGR GLYYGSYLYK ETWNVGVVLL LLVMMTAFVG YVLPWGQMSF WGATVITNLL SAVPYVGNTL VQWIWGGFSV DNATLTRFFA FHFLLPFIIA AMTVIHLLFL HETGSNNPTG LNSDADKISF HPYFSYKDLL GFTALLIGLT SLALFSPNLL GDPDNFTPAN PLVTPPHIKP EWYFLFAYAI LRSIPNKLGG VLALLASILV LMVVPILHTS KQRGLTFRPL TQFLFWTLVA DVIILTWIGG MPVEHPFIII GQVASFLYFF LFLVLTPLAG WLENKALGWA //