ID A0A3Q7RK19_VULVU Unreviewed; 313 AA. AC A0A3Q7RK19; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 02-OCT-2024, entry version 28. DE SubName: Full=WD repeat-containing protein 82 {ECO:0000313|RefSeq:XP_025842626.1}; GN Name=WDR82 {ECO:0000313|RefSeq:XP_025842626.1}; OS Vulpes vulpes (Red fox). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes. OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025842626.1}; RN [1] RP IDENTIFICATION. RG RefSeq; RL Submitted (JAN-2019) to UniProtKB. RN [2] {ECO:0000313|RefSeq:XP_025842626.1} RP IDENTIFICATION. RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025842626.1}; RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025842626.1}; RG RefSeq; RL Submitted (JUN-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC -!- SIMILARITY: Belongs to the WD repeat SWD2 family. CC {ECO:0000256|ARBA:ARBA00005616}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_025842626.1; XM_025986841.1. DR AlphaFoldDB; A0A3Q7RK19; -. DR SMR; A0A3Q7RK19; -. DR STRING; 9627.ENSVVUP00000037523; -. DR Ensembl; ENSVVUT00000049292; ENSVVUP00000037523; ENSVVUG00000026827. DR KEGG; vvp:112910634; -. DR OMA; HNEGYIR; -. DR OrthoDB; 176818at2759; -. DR Proteomes; UP000286640; Unplaced. DR GO; GO:0000785; C:chromatin; IEA:Ensembl. DR GO; GO:0000781; C:chromosome, telomeric region; IEA:Ensembl. DR GO; GO:0005730; C:nucleolus; IEA:Ensembl. DR GO; GO:0072357; C:PTW/PP1 phosphatase complex; IEA:Ensembl. DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:Ensembl. DR GO; GO:0003682; F:chromatin binding; IEA:TreeGrafter. DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-KW. DR GO; GO:0110064; P:lncRNA catabolic process; IEA:Ensembl. DR GO; GO:0032785; P:negative regulation of DNA-templated transcription, elongation; IEA:Ensembl. DR GO; GO:0140744; P:negative regulation of lncRNA transcription; IEA:Ensembl. DR GO; GO:0071027; P:nuclear RNA surveillance; IEA:Ensembl. DR CDD; cd00200; WD40; 1. DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2. DR InterPro; IPR020472; G-protein_beta_WD-40_rep. DR InterPro; IPR037867; Swd2/WDR82. DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf. DR InterPro; IPR036322; WD40_repeat_dom_sf. DR InterPro; IPR001680; WD40_rpt. DR PANTHER; PTHR19861:SF0; WD REPEAT-CONTAINING PROTEIN 82; 1. DR PANTHER; PTHR19861; WD40 REPEAT PROTEIN SWD2; 1. DR Pfam; PF00400; WD40; 3. DR PRINTS; PR00320; GPROTEINBRPT. DR SMART; SM00320; WD40; 6. DR SUPFAM; SSF50978; WD40 repeat-like; 1. DR PROSITE; PS50082; WD_REPEATS_2; 3. DR PROSITE; PS50294; WD_REPEATS_REGION; 2. PE 3: Inferred from homology; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Reference proteome {ECO:0000313|Proteomes:UP000286640}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Transcription {ECO:0000256|ARBA:ARBA00022472}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00022472}; KW Transcription termination {ECO:0000256|ARBA:ARBA00022472}; KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE- KW ProRule:PRU00221}. FT REPEAT 17..58 FT /note="WD" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221" FT REPEAT 103..138 FT /note="WD" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221" FT REPEAT 235..276 FT /note="WD" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221" SQ SEQUENCE 313 AA; 35079 MW; FD3505A9B89863A0 CRC64; MKLTDSVLRS FRVAKVFREN SDKINCFDFS PNGETVISSS DDDSIVLYDC QEGKPKRTLY SKKYGVDLIR YTHAANTVVY SSNKIDDTIR YLSLHDNKYI RYFPGHSKRV VALSMSPVDD TFISGSLDKT IRLWDLRSPN CQGLMHLQGK PVCSFDPEGL IFAAGVNSEM VKLYDLRSFD KGPFATFKMQ YDRTCEWTGL KFSNDGKLIL ISTNGSFIRL IDAFKGVVMH TFGGYANSKA VTLEASFTPD SQFIMIGSED GKIHVWNGES GIKVAVLDGK HTGPITCLQF NPKFMTFASA CSNMAFWLPT IDD //