ID A0A3Q3KVE3_9TELE Unreviewed; 215 AA. AC A0A3Q3KVE3; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 26-FEB-2020, entry version 8. DE SubName: Full=Insulin-like growth factor 2b {ECO:0000313|Ensembl:ENSMAMP00000005327}; OS Mastacembelus armatus (zig-zag eel). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus. OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000005327, ECO:0000313|Proteomes:UP000261640}; RN [1] {ECO:0000313|Ensembl:ENSMAMP00000005327, ECO:0000313|Proteomes:UP000261640} RP NUCLEOTIDE SEQUENCE. RA Datahose.; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSMAMP00000005327} RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2019) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU000406, CC ECO:0000256|SAAS:SAAS00822014}. CC -!- SIMILARITY: Belongs to the insulin family. CC {ECO:0000256|RuleBase:RU000406, ECO:0000256|SAAS:SAAS00542063}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSMAMT00000005465; ENSMAMP00000005327; ENSMAMG00000003599. DR GeneTree; ENSGT00940000160745; -. DR Proteomes; UP000261640; Whole Genome Shotgun Assembly. DR GO; GO:0005615; C:extracellular space; IEA:InterPro. DR GO; GO:0008083; F:growth factor activity; IEA:InterPro. DR GO; GO:0005179; F:hormone activity; IEA:InterPro. DR GO; GO:0005159; F:insulin-like growth factor receptor binding; IEA:Ensembl. DR GO; GO:0031101; P:fin regeneration; IEA:Ensembl. DR GO; GO:0030900; P:forebrain development; IEA:Ensembl. DR GO; GO:0030903; P:notochord development; IEA:Ensembl. DR GO; GO:0048793; P:pronephros development; IEA:Ensembl. DR GO; GO:0001756; P:somitogenesis; IEA:Ensembl. DR InterPro; IPR022334; IGF2. DR InterPro; IPR013576; IGF2_C. DR InterPro; IPR016179; Insulin-like. DR InterPro; IPR022350; Insulin-like_growth_factor. DR InterPro; IPR036438; Insulin-like_sf. DR InterPro; IPR022353; Insulin_CS. DR InterPro; IPR022352; Insulin_family. DR Pfam; PF08365; IGF2_C; 1. DR Pfam; PF00049; Insulin; 1. DR PRINTS; PR02002; INSLNLIKEGF. DR PRINTS; PR02006; INSLNLIKEGF2. DR PRINTS; PR00276; INSULINFAMLY. DR SMART; SM00078; IlGF; 1. DR SUPFAM; SSF56994; SSF56994; 1. DR PROSITE; PS00262; INSULIN; 1. PE 3: Inferred from homology; KW Disulfide bond {ECO:0000256|PIRSR:PIRSR622350-50}; KW Reference proteome {ECO:0000313|Proteomes:UP000261640}; KW Secreted {ECO:0000256|RuleBase:RU000406, ECO:0000256|SAAS:SAAS00822033}. FT DOMAIN 53..110 FT /note="IlGF" FT /evidence="ECO:0000259|SMART:SM00078" FT DISULFID 56..97 FT /evidence="ECO:0000256|PIRSR:PIRSR622350-50" FT DISULFID 68..110 FT /evidence="ECO:0000256|PIRSR:PIRSR622350-50" FT DISULFID 96..101 FT /evidence="ECO:0000256|PIRSR:PIRSR622350-50" SQ SEQUENCE 215 AA; 24702 MW; E836C5E5A2ECC3DC CRC64; METQQRHGHH TLCHTCRRTQ NSKMKDKKMS SSSRSLLFAL ALTLYVVEMA SAETLCGGEL VDALQFVCDD RGFYFSRPTS RGNNRRSQSR GIVEECCFRS CDLNLLEQYC AKPAKSERDL SATSLQVIPV MPALKQEVPR KQHVTVKYSK YEVWQRKAAQ RLRRGVPGIL RAKKFRRQAE KIKAQEQAMF HRPLISLPSK LPPILLATDH YVNHK //