ID   A0A3Q3DAX7_HIPCM        Unreviewed;       457 AA.
AC   A0A3Q3DAX7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=medium-chain acyl-CoA dehydrogenase {ECO:0000256|ARBA:ARBA00012033};
DE            EC=1.3.8.7 {ECO:0000256|ARBA:ARBA00012033};
OS   Hippocampus comes (Tiger tail seahorse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Syngnathiaria; Syngnathiformes; Syngnathoidei; Syngnathidae; Hippocampus.
OX   NCBI_TaxID=109280 {ECO:0000313|Ensembl:ENSHCOP00000007494.1, ECO:0000313|Proteomes:UP000264820};
RN   [1] {ECO:0000313|Ensembl:ENSHCOP00000007494.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974,
CC         ECO:0000256|RuleBase:RU362125};
CC   -!- PATHWAY: Lipid metabolism; mitochondrial fatty acid beta-oxidation.
CC       {ECO:0000256|ARBA:ARBA00005198}.
CC   -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009347, ECO:0000256|RuleBase:RU362125}.
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DR   AlphaFoldDB; A0A3Q3DAX7; -.
DR   STRING; 109280.ENSHCOP00000007494; -.
DR   Ensembl; ENSHCOT00000001900.1; ENSHCOP00000007494.1; ENSHCOG00000009552.1.
DR   GeneTree; ENSGT00940000164410; -.
DR   Proteomes; UP000264820; Unplaced.
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 1.
DR   Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR   Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR   InterPro; IPR006089; Acyl-CoA_DH_CS.
DR   InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR   InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR   InterPro; IPR036250; AcylCo_DH-like_C.
DR   InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR   InterPro; IPR013786; AcylCoA_DH/ox_N.
DR   InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR   InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR   PANTHER; PTHR48083; MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED; 1.
DR   PANTHER; PTHR48083:SF6; ZGC:85777; 1.
DR   Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR   Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR   Pfam; PF02771; Acyl-CoA_dh_N; 1.
DR   SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
DR   PROSITE; PS00073; ACYL_COA_DH_2; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU362125};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|RuleBase:RU362125};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU362125};
KW   Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT   DOMAIN          90..188
FT                   /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02771"
FT   DOMAIN          196..291
FT                   /note="Acyl-CoA oxidase/dehydrogenase middle"
FT                   /evidence="ECO:0000259|Pfam:PF02770"
FT   DOMAIN          303..449
FT                   /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00441"
SQ   SEQUENCE   457 AA;  50306 MW;  21B6757FC15DB08F CRC64;
     MRIITQTAMA LHCGAVRLNA LIRTRPFFKC ASFGLRSFAD HASSPKVASN APETSGDHVL
     YTPEHFALKD SLKKIAEILG GDVSATQQEN IIDQEINPYV DQWEAEGKFP AHKIFKILGN
     AGFLGVNKPV EYGGMGLDYS YSVAVSEELG HIRCGGIPMA IGVQTDMATP ALARFGSAEL
     KKEFLLPSIL GDKVACLGVS EVGAGSDVSN IKTKAVRKGD DYVINGGKMW TTNGTQADWM
     CLLANTSDGP PHRNKSLICL PMNLPGVHIA RKIDKLGMWS SDTAEVFFED VRVPCKNVIG
     QEGMGFTYQM LQFQEERLWA VANIVTTMDV VIRETIHYTR QRKIFSHPVL YHQAVHFRLA
     ELQTEVELLR ALLYQATALY IKGNDVTKMA SMAKLKAGRL AREVGDGCLQ YWGGMGFTSD
     VLVSRFYRDS RLLSIGGGAD EVMLGIICKY MDILPKK
//