ID A0A3Q1LSX9_BOVIN Unreviewed; 1095 AA. AC A0A3Q1LSX9; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 16-OCT-2019, entry version 6. DE SubName: Full=Formin like 2 {ECO:0000313|Ensembl:ENSBTAP00000063529}; GN Name=FMNL2 {ECO:0000313|Ensembl:ENSBTAP00000063529, GN ECO:0000313|VGNC:VGNC:29047}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000063529, ECO:0000313|Proteomes:UP000009136}; RN [1] {ECO:0000313|Ensembl:ENSBTAP00000063529, ECO:0000313|Proteomes:UP000009136} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000063529, RC ECO:0000313|Proteomes:UP000009136}; RX PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42; RA Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., RA Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., RA Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.; RT "A whole-genome assembly of the domestic cow, Bos taurus."; RL Genome Biol. 10:R42.01-R42.10(2009). RN [2] {ECO:0000313|Ensembl:ENSBTAP00000063529} RP IDENTIFICATION. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000063529}; RG Ensembl; RL Submitted (JAN-2019) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSBTAT00000073284; ENSBTAP00000063529; ENSBTAG00000026851. DR VGNC; VGNC:29047; FMNL2. DR GeneTree; ENSGT00940000155515; -. DR Proteomes; UP000009136; Chromosome 2. DR GO; GO:0003779; F:actin binding; IEA:InterPro. DR GO; GO:0017048; F:Rho GTPase binding; IEA:InterPro. DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:Ensembl. DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:Ensembl. DR Gene3D; 1.20.58.2220; -; 1. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR015425; FH2_Formin. DR InterPro; IPR042201; FH2_Formin_sf. DR InterPro; IPR010472; FH3_dom. DR InterPro; IPR027656; FMNL2. DR InterPro; IPR014768; GBD/FH3_dom. DR InterPro; IPR010473; GTPase-bd. DR PANTHER; PTHR45857:SF5; PTHR45857:SF5; 1. DR Pfam; PF06367; Drf_FH3; 1. DR Pfam; PF06371; Drf_GBD; 2. DR Pfam; PF02181; FH2; 1. DR SMART; SM01139; Drf_FH3; 1. DR SMART; SM01140; Drf_GBD; 1. DR SMART; SM00498; FH2; 1. DR SUPFAM; SSF48371; SSF48371; 1. DR PROSITE; PS51444; FH2; 1. DR PROSITE; PS51232; GBD_FH3; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000009136}; KW Reference proteome {ECO:0000313|Proteomes:UP000009136}. FT DOMAIN 23 469 GBD/FH3. {ECO:0000259|PROSITE:PS51232}. FT DOMAIN 617 1008 FH2. {ECO:0000259|PROSITE:PS51444}. FT REGION 521 602 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COILED 93 113 {ECO:0000256|SAM:Coils}. FT COILED 381 478 {ECO:0000256|SAM:Coils}. FT COILED 897 917 {ECO:0000256|SAM:Coils}. FT COILED 982 1013 {ECO:0000256|SAM:Coils}. FT COMPBIAS 521 537 Pro-rich. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 546 600 Pro-rich. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 1095 AA; 124214 MW; 410E9DE51208AB03 CRC64; MGNAGSMDSQ QTDFRAHNVP LKLPMPEPGE LEERFAIVLN AMNLPPDKAR LLRQYDNEKK WELICDQERF QVKNPPHTYI QKLKGYLDPA VTRKKFRRRV QESTQVLREL EISLRTNHIG WVREFLNEEN KGLDVLVEYL SFAQYAVTFD FESVESTVES SVDKSKPWSR SIEDLHRGSN LPSPVGNSVS RSGRHSALRY NTLPSRRTLK NSRLVSKKDD VHVCIMCLRA IMNYQYGFNM VMSHPHAVNE IALSLNNKNP RTKALVLELL AAVCLVRGGH EIILSAFDNF KEVCGEKQRF EKLMEHFRNE DNNIDFMVAS MQFINIVVHS VEDMNFRVHL QYEFTKLGLD EYLDKLKHTE SDKLQVQIQA YLDNVFDVGA LLEDAETKNA ALERVEELEE NISHLSEKLQ DTENEAMSKI VELEKQLMQR NKELDVVREI YKDANTQVHT LRKMVKEKEE AIQRQSTLEK KIHELEKQGT IKIQKKGDGD IAILPVVASG TLPTGSEVAV GNFVGPVMGA PSSGPLPPPP PPLPLSSDAP EAVQNGPATP PVPPPPPPPP PPPPPPPPPP PPPLPGPAAE TLPAPPLPPP PPPSAPPLPG TSSPTVVFNS GLAAVKIKKP IKTKFRMPVF NWVALKPNQI NGTVFNEIDD ERILEDLNVD EFEEIFKTKA QGPAIDLSSS KQKITQKGSN KVTLLEANRA KNLAITLRKA GKTAEEICKA IHVFDLKTLP VDFVECLMRF LPTENEVKVL RLYERERKPL ENLSDEDRFM MQFSKIERLM QKMTIMAFIG NFTESIQMLT PQLHSIIAAS VSIKSSQKLK KILEIILALG NYMNSSKRGA VYGFKLQSLD LLLDTKSTDR KQTLLHYISN VVKEKYQQVS LFYNELHYVE KAAAVSLENV LLDVKELQRG MDLTKREYTM HDHNTLLKEF IFNNEGKLKK LQDDAKIAQD AFDDVVKYFG ENPKTTPPSV FFPVFVRFVK AYKQAEEENE LRKKQEQALM EKLLEQEALL EQQDPKSPSH KSKRQQQELI AELRRRQVKD NRHVYEGKDG AIEDIITALK KNNITKFPNV HSRVRISSST PVVEDTQSWQ ASLFT //