ID A0A3Q0R9C4_AMPCI Unreviewed; 292 AA. AC A0A3Q0R9C4; DT 10-APR-2019, integrated into UniProtKB/TrEMBL. DT 10-APR-2019, sequence version 1. DT 02-JUN-2021, entry version 12. DE SubName: Full=Fer (fps/fes related) tyrosine kinase {ECO:0000313|Ensembl:ENSACIP00000007186}; OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids; OC Cichlasomatinae; Heroini; Amphilophus. OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000007186, ECO:0000313|Proteomes:UP000261340}; RN [1] {ECO:0000313|Ensembl:ENSACIP00000007186} RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2019) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSACIT00000007400; ENSACIP00000007186; ENSACIG00000005631. DR GeneTree; ENSGT00940000154997; -. DR Proteomes; UP000261340; Unplaced. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0005154; F:epidermal growth factor receptor binding; IEA:InterPro. DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. DR GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:InterPro. DR GO; GO:0008283; P:cell population proliferation; IEA:InterPro. DR GO; GO:0030335; P:positive regulation of cell migration; IEA:InterPro. DR GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:InterPro. DR GO; GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IEA:InterPro. DR InterPro; IPR028539; Fer. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom. DR PANTHER; PTHR24418:SF227; PTHR24418:SF227; 1. DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1. DR PRINTS; PR00109; TYRKINASE. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141}; KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141}. FT DOMAIN 34..289 FT /note="Protein kinase" FT /evidence="ECO:0000259|PROSITE:PS50011" FT BINDING 63 FT /note="ATP" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141" SQ SEQUENCE 292 AA; 33303 MW; B4B20C29E553B2E1 CRC64; HHFTTKQVIT KKSGVVLHNP VVKDKKWILN HEDVVLGDLL GKGNFGEVYK GTLQRDKTPV AVKTCKEDLP PELKIRFLSE ARILKQYDHP NIVKLIGVCT QRQPIYIVME LVPGGDFLSF LRKKKDELKT KQLVRFAVDA AAGMAYLESK NCIHSVLAAR NCLVGENSVL KISDFGMSRQ EDDGVYSSSG LKQIPIKWTA PEALNYGRYS SESDVWSYGI LLWETFSLGV CPYLGMTNQQ AREQVEKGYR MVCPQRCPDD VYKVMQRCWQ YNPEDRPKFS ELQRDLAAIK KK //