ID A0A3P8SFY5_AMPPE Unreviewed; 776 AA. AC A0A3P8SFY5; DT 13-FEB-2019, integrated into UniProtKB/TrEMBL. DT 13-FEB-2019, sequence version 1. DT 07-OCT-2020, entry version 9. DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAPEP00000010694}; OS Amphiprion percula (Orange clownfish) (Lutjanus percula). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Pomacentridae; Amphiprion. OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000010694}; RN [1] {ECO:0000313|Ensembl:ENSAPEP00000010694} RP NUCLEOTIDE SEQUENCE. RA Lehmann R.; RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome RT of the orange clownfish Amphiprion percula."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSAPEP00000010694} RP IDENTIFICATION. RG Ensembl; RL Submitted (DEC-2018) to UniProtKB. CC -!- FUNCTION: Cadherins are calcium-dependent cell adhesion proteins. CC {ECO:0000256|RuleBase:RU004357}. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251, CC ECO:0000256|RuleBase:RU003318}; Single-pass type I membrane protein CC {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}. CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane CC protein {ECO:0000256|ARBA:ARBA00004479}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSAPET00000010984; ENSAPEP00000010694; ENSAPEG00000007661. DR GeneTree; ENSGT00940000154187; -. DR Proteomes; UP000265080; Chromosome 22. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro. DR Gene3D; 4.10.900.10; -; 1. DR InterPro; IPR039808; Cadherin. DR InterPro; IPR002126; Cadherin-like_dom. DR InterPro; IPR015919; Cadherin-like_sf. DR InterPro; IPR020894; Cadherin_CS. DR InterPro; IPR000233; Cadherin_cytoplasmic-dom. DR InterPro; IPR027397; Catenin_binding_dom_sf. DR PANTHER; PTHR24027; PTHR24027; 1. DR Pfam; PF00028; Cadherin; 5. DR Pfam; PF01049; Cadherin_C; 1. DR PRINTS; PR00205; CADHERIN. DR SMART; SM00112; CA; 5. DR SUPFAM; SSF49313; SSF49313; 5. DR PROSITE; PS00232; CADHERIN_1; 2. PE 4: Predicted; KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|RuleBase:RU003318}; KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889, KW ECO:0000256|RuleBase:RU003318}; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000265080}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, KW ECO:0000256|RuleBase:RU003318, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT SIGNAL 1..21 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 22..776 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5018035880" FT TRANSMEM 601..622 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 71..152 FT /note="CA" FT /evidence="ECO:0000259|SMART:SM00112" FT DOMAIN 176..261 FT /note="CA" FT /evidence="ECO:0000259|SMART:SM00112" FT DOMAIN 281..371 FT /note="CA" FT /evidence="ECO:0000259|SMART:SM00112" FT DOMAIN 394..475 FT /note="CA" FT /evidence="ECO:0000259|SMART:SM00112" FT DOMAIN 498..582 FT /note="CA" FT /evidence="ECO:0000259|SMART:SM00112" SQ SEQUENCE 776 AA; 86134 MW; FCFC0B23E4FC39DB CRC64; MIANQILLLL LMLSVLPSSA ALPLSPGNIG NLFGTSESDG KILQRSKRGW MWNQFFLLEE YTGNDHQYVG KLHSNMDKND GNVKYVLTGD GAGTLFLIDE KSGDIHATKR LDREEKAMYT LHAKVLDRNT NAELEPDTEF NIKIHDINDN APKFAKEIYF ASVPEMSEVG TSVVTVTATD ADDQTYGNSA KLVYSILQGQ PYFSVDSENG TIKTALPGMD RELKENYQVV IQAKDMAGQM GGLSGTTTVS ITLSDVNDSP PRFANLTAVE STDIGGAIGR IKADDPDVGH NAEMEYSIVG GHDIFNIITD QTTQEGVIII KKALDYESKR DYEFRVEVKN TYLDARFIHG LQFKDYATVK VTVEDVDEPP IFTRNPYIIE VHEDTAAGSF VGVVSARDPD ADNKPVKYSI DRHTDLERLF NIDSVNGTIT TLKALDREMS KWHNISVVAT EINNPRQTTR VPVFIKVLDV NDNAPEFAMS YDTFVCENVK AGQLIQTISA VDTDEPLVGH KFVFSISATN PNFTIVDRED NTANILTRRG GFSRREMSMY FLPVVISDND YPIQSSTSTL IVRVCACDSH GNMQSCNPEV LPFSDGLTTG ALVAILLCVI ILLMIVVLFA ALRRQRKKEP LIISKEDVRD NVVSYNDEGG GEEDTQAFDI GTLRNPEVMD ANKLRRDIIP EMLFPFRRTS PIKDNTDVRD FINGRLQEND SDPTAPPYDS LATYAYEGSG SLAESLSSLE SAATEGDQDY DYLSNWGPQF KKLAEMYIGK SPDRET //