ID A0A3P8SFY5_AMPPE Unreviewed; 776 AA. AC A0A3P8SFY5; DT 13-FEB-2019, integrated into UniProtKB/TrEMBL. DT 13-FEB-2019, sequence version 1. DT 03-JUL-2019, entry version 5. DE SubName: Full=Cadherin 10 {ECO:0000313|Ensembl:ENSAPEP00000010694}; GN Name=CDH10 {ECO:0000313|Ensembl:ENSAPEP00000010694}; OS Amphiprion percula (Orange clownfish) (Lutjanus percula). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Pomacentridae; Amphiprion. OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000010694, ECO:0000313|Proteomes:UP000265080}; RN [1] {ECO:0000313|Ensembl:ENSAPEP00000010694, ECO:0000313|Proteomes:UP000265080} RP NUCLEOTIDE SEQUENCE. RA Lehmann R.; RT "Finding Nemo's genes: A chromosome-scale reference assembly of the RT genome of the orange clownfish Amphiprion percula."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSAPEP00000010694} RP IDENTIFICATION. RG Ensembl; RL Submitted (DEC-2018) to UniProtKB. CC -!- FUNCTION: Cadherins are calcium-dependent cell adhesion proteins. CC {ECO:0000256|RuleBase:RU004357}. CC -!- SUBCELLULAR LOCATION: Cell membrane CC {ECO:0000256|RuleBase:RU003318, ECO:0000256|SAAS:SAAS00544042}; CC Single-pass type I membrane protein CC {ECO:0000256|RuleBase:RU003318, ECO:0000256|SAAS:SAAS00544042}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSAPET00000010984; ENSAPEP00000010694; ENSAPEG00000007661. DR GeneTree; ENSGT00940000154187; -. DR Proteomes; UP000265080; Chromosome 22. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro. DR Gene3D; 4.10.900.10; -; 1. DR InterPro; IPR039808; Cadherin. DR InterPro; IPR002126; Cadherin-like_dom. DR InterPro; IPR015919; Cadherin-like_sf. DR InterPro; IPR020894; Cadherin_CS. DR InterPro; IPR000233; Cadherin_cytoplasmic-dom. DR InterPro; IPR027397; Catenin_binding_dom_sf. DR PANTHER; PTHR24027; PTHR24027; 1. DR Pfam; PF00028; Cadherin; 5. DR Pfam; PF01049; Cadherin_C; 1. DR PRINTS; PR00205; CADHERIN. DR SMART; SM00112; CA; 5. DR SUPFAM; SSF49313; SSF49313; 5. DR PROSITE; PS00232; CADHERIN_1; 2. PE 4: Predicted; KW Calcium {ECO:0000256|RuleBase:RU003318, KW ECO:0000256|SAAS:SAAS00020193}; KW Cell adhesion {ECO:0000256|RuleBase:RU003318, KW ECO:0000256|SAAS:SAAS00307165}; KW Cell membrane {ECO:0000256|SAAS:SAAS00307127}; KW Complete proteome {ECO:0000313|Proteomes:UP000265080}; KW Membrane {ECO:0000256|SAAS:SAAS00020159, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000265080}; KW Repeat {ECO:0000256|SAAS:SAAS00226229}; KW Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|RuleBase:RU003318, KW ECO:0000256|SAAS:SAAS00556032, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00554877, KW ECO:0000256|SAM:Phobius}. FT SIGNAL 1 21 {ECO:0000256|SAM:SignalP}. FT CHAIN 22 776 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5018035880. FT TRANSMEM 601 622 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 71 152 CA. {ECO:0000259|SMART:SM00112}. FT DOMAIN 176 261 CA. {ECO:0000259|SMART:SM00112}. FT DOMAIN 281 371 CA. {ECO:0000259|SMART:SM00112}. FT DOMAIN 394 475 CA. {ECO:0000259|SMART:SM00112}. FT DOMAIN 498 582 CA. {ECO:0000259|SMART:SM00112}. SQ SEQUENCE 776 AA; 86134 MW; FCFC0B23E4FC39DB CRC64; MIANQILLLL LMLSVLPSSA ALPLSPGNIG NLFGTSESDG KILQRSKRGW MWNQFFLLEE YTGNDHQYVG KLHSNMDKND GNVKYVLTGD GAGTLFLIDE KSGDIHATKR LDREEKAMYT LHAKVLDRNT NAELEPDTEF NIKIHDINDN APKFAKEIYF ASVPEMSEVG TSVVTVTATD ADDQTYGNSA KLVYSILQGQ PYFSVDSENG TIKTALPGMD RELKENYQVV IQAKDMAGQM GGLSGTTTVS ITLSDVNDSP PRFANLTAVE STDIGGAIGR IKADDPDVGH NAEMEYSIVG GHDIFNIITD QTTQEGVIII KKALDYESKR DYEFRVEVKN TYLDARFIHG LQFKDYATVK VTVEDVDEPP IFTRNPYIIE VHEDTAAGSF VGVVSARDPD ADNKPVKYSI DRHTDLERLF NIDSVNGTIT TLKALDREMS KWHNISVVAT EINNPRQTTR VPVFIKVLDV NDNAPEFAMS YDTFVCENVK AGQLIQTISA VDTDEPLVGH KFVFSISATN PNFTIVDRED NTANILTRRG GFSRREMSMY FLPVVISDND YPIQSSTSTL IVRVCACDSH GNMQSCNPEV LPFSDGLTTG ALVAILLCVI ILLMIVVLFA ALRRQRKKEP LIISKEDVRD NVVSYNDEGG GEEDTQAFDI GTLRNPEVMD ANKLRRDIIP EMLFPFRRTS PIKDNTDVRD FINGRLQEND SDPTAPPYDS LATYAYEGSG SLAESLSSLE SAATEGDQDY DYLSNWGPQF KKLAEMYIGK SPDRET //