ID   A0A3P8PCA6_ASTCA        Unreviewed;       203 AA.
AC   A0A3P8PCA6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   25-MAY-2022, entry version 15.
DE   SubName: Full=Amino-terminal enhancer of split-like {ECO:0000313|Ensembl:ENSACLP00000014624};
GN   Name=TLE5 {ECO:0000313|Ensembl:ENSACLP00000014624};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000014624, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000014624, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000014624}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (DEC-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the WD repeat Groucho/TLE family.
CC       {ECO:0000256|ARBA:ARBA00005969}.
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DR   STRING; 8154.ENSACLP00000014624; -.
DR   Ensembl; ENSACLT00000014973.1; ENSACLP00000014624.1; ENSACLG00000009962.1.
DR   GeneTree; ENSGT01030000234519; -.
DR   OMA; GDTHQDD; -.
DR   Proteomes; UP000265100; Chromosome 19.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR005617; Groucho/TLE_N.
DR   InterPro; IPR009146; Groucho_enhance.
DR   PANTHER; PTHR10814; PTHR10814; 1.
DR   Pfam; PF03920; TLE_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          18..132
FT                   /note="TLE_N"
FT                   /evidence="ECO:0000259|Pfam:PF03920"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          175..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          26..53
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        180..203
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   203 AA;  22680 MW;  9E97916122507F1B CRC64;
     MMFPQSRHSA SSQSSQPLKF TTSDSCDRIK DEFQFLQAQY HSLKLECDKL ASEKSEMQRH
     YIMYYEMSYG LNIEMHKQAE IVKRLNGICA QVLPYLSQEH QQQVMGAIER AKQVTPPEMN
     SIIRQQLQVQ HLSQLQGLAL PVAPLPLGLT PPTLPAVSSS SGLLSLSSIL ANYSHGQPPL
     AKEDKARDVA ERAPRGDDGD KSD
//