ID A0A3P8NYW9_ASTCA Unreviewed; 1205 AA. AC A0A3P8NYW9; DT 13-FEB-2019, integrated into UniProtKB/TrEMBL. DT 13-FEB-2019, sequence version 1. DT 25-MAY-2022, entry version 11. DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878}; OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; OC Pseudocrenilabrinae; Haplochromini; Astatotilapia. OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000009938, ECO:0000313|Proteomes:UP000265100}; RN [1] {ECO:0000313|Ensembl:ENSACLP00000009938, ECO:0000313|Proteomes:UP000265100} RP NUCLEOTIDE SEQUENCE. RA Datahose.; RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSACLP00000009938} RP IDENTIFICATION. RG Ensembl; RL Submitted (DEC-2018) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSACLT00000010172.1; ENSACLP00000009938.1; ENSACLG00000006792.1. DR GeneTree; ENSGT00940000163737; -. DR OMA; FWSNQWG; -. DR Proteomes; UP000265100; Chromosome 2. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0003824; F:catalytic activity; IEA:InterPro. DR Gene3D; 3.60.10.10; -; 1. DR InterPro; IPR043502; DNA/RNA_pol_sf. DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf. DR InterPro; IPR005135; Endo/exonuclease/phosphatase. DR InterPro; IPR000477; RT_dom. DR InterPro; IPR026960; RVT-Znf. DR Pfam; PF14529; Exo_endo_phos_2; 1. DR Pfam; PF00078; RVT_1; 1. DR Pfam; PF13966; zf-RVT; 1. DR SUPFAM; SSF56219; SSF56219; 1. DR SUPFAM; SSF56672; SSF56672; 1. DR PROSITE; PS50878; RT_POL; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 1150..1172 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 499..765 FT /note="Reverse transcriptase" FT /evidence="ECO:0000259|PROSITE:PS50878" FT COILED 334..354 FT /evidence="ECO:0000256|SAM:Coils" SQ SEQUENCE 1205 AA; 140487 MW; 6AD67DB51079D1F6 CRC64; MLNVNICFGS LNVRGLRESV KRKALFLYCK GKKSNCIFLQ ETHSSDSDVS FWSNQWGSKI LFSHGSMRSG GVAILFNNFP GDLVIQRTDL NGHWLIAVMR VESLFFILVN VYGYNNESQN KIMLEDITSN IFELKGRYPT EYILMGGDWN MTPDEWTDRW PSRTGRPQKN NLIIEFLINN NLTDIWRVRN PEIKSFSWFK PNGACKSRID YWLGSDIILS HTVKVAMSNA PLSDHCFIEL CLESEIRQSN KRTYWKFNAK LLQNEDYCNI VKKIIKDIMA DHLIVGYISK WEFIKFKIRE FSIQFSKNIS QKQREYECKL FQEITYCCSK DDLNTQERSK LMELQTKLDQ LYLNKAEGAF VRSQAKWIEE GERNSSYFFN LEKSRQKRNF ISSLLIDGIE CDDPKILENE TYTFYSNLYS SQFSQADCDV FFDQIDNLIP KIDESFKELC ESDFRIEELD ASVKKMALNK SPGPDGLTVN FFQFFWEDLR KILFKAILAS IEKGELMSSM KQGLITLIPK PNKDKRQLDN LRPITLLNTD YKIFSSSVAT RLKQGVSSII SETQSGFLKD RNIHNNIRLV LDLLDYNDLI SDDSFILFLD FYKAFDSVEH PFILETLTRF GFGDKFRKII DILYNDINSS VSLGYGTGKR FGVKRGIRQG CGSSPLLFIM VVEMLAILIK NSSVAGIEIM DNSLIISQLA DDTTLFLKNE HQIPLVKQII TTFSKASGLK LHLNKCELLA LKECNSQLLY DIKVKKEVKY LGITISKDHK VLEKVNILDN VDKCKTILNK WLQRDITIFG RILLTKMDSL SRFIYPAYSL SISNKVIKTI NSLNLNFIWR NKCHYISKDD LVKPYIEGGG NAIDFDIMNG VLKLKWLKSF LNNPHSIWFF IPSKVFNTLG GIDFLLKCDF EITKLPAKLS EFHKQVLLYW KMLFKHNFTP HNSPIWNNRY ILMNRKSIFI QDWLSKGVWA IAHFVDEEGH VLGHQDFCQK FNIQCSKSKF NRVIKSIPLS LKNIVVNDII YSDISPKLRQ LYIDGIRFCD VKCNNKFLRS LLRSLYSPNL LRRNYILKDF QREEIEKIRT DYITFPIPPK GKEVQFKILN KIYPTNRLLS DRFKIETGNC VFCETEEEDL DHLFFLCNFI QIFWLDFHTW LYSSGIQITP FTLNMIMFGV FLKEKKANYG VNVLLILCKY FIHKCRFCKT KPTLA //