ID A0A3M0BIU0_9AQUI Unreviewed; 304 AA. AC A0A3M0BIU0; DT 13-FEB-2019, integrated into UniProtKB/TrEMBL. DT 13-FEB-2019, sequence version 1. DT 08-MAY-2019, entry version 3. DE RecName: Full=Signal recognition particle receptor FtsY {ECO:0000256|HAMAP-Rule:MF_00920}; DE Short=SRP receptor {ECO:0000256|HAMAP-Rule:MF_00920}; GN Name=ftsY {ECO:0000256|HAMAP-Rule:MF_00920}; GN ORFNames=CLV39_0968 {ECO:0000313|EMBL:RMA97310.1}; OS Hydrogenothermus marinus. OC Bacteria; Aquificae; Aquificales; Hydrogenothermaceae; OC Hydrogenothermus. OX NCBI_TaxID=133270 {ECO:0000313|EMBL:RMA97310.1, ECO:0000313|Proteomes:UP000280842}; RN [1] {ECO:0000313|EMBL:RMA97310.1, ECO:0000313|Proteomes:UP000280842} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=VM1 {ECO:0000313|EMBL:RMA97310.1, RC ECO:0000313|Proteomes:UP000280842}; RA Goeker M.; RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II RT (KMG-II): from individual species to whole genera."; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in targeting and insertion of nascent membrane CC proteins into the cytoplasmic membrane. Acts as a receptor for the CC complex formed by the signal recognition particle (SRP) and the CC ribosome-nascent chain (RNC). {ECO:0000256|HAMAP-Rule:MF_00920}. CC -!- SUBUNIT: Part of the signal recognition particle protein CC translocation system, which is composed of SRP and FtsY. CC {ECO:0000256|HAMAP-Rule:MF_00920}. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP- CC Rule:MF_00920}; Peripheral membrane protein {ECO:0000256|HAMAP- CC Rule:MF_00920}; Cytoplasmic side {ECO:0000256|HAMAP- CC Rule:MF_00920}. Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00920}. CC -!- SIMILARITY: Belongs to the GTP-binding SRP family. FtsY subfamily. CC {ECO:0000256|HAMAP-Rule:MF_00920}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:RMA97310.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; REFO01000011; RMA97310.1; -; Genomic_DNA. DR Proteomes; UP000280842; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0031226; C:intrinsic component of plasma membrane; IEA:UniProtKB-UniRule. DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule. DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule. DR GO; GO:0006612; P:protein targeting to membrane; IEA:UniProtKB-UniRule. DR Gene3D; 1.20.120.140; -; 1. DR HAMAP; MF_00920; FtsY; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR013822; Signal_recog_particl_SRP54_hlx. DR InterPro; IPR004390; SR_rcpt_FtsY. DR InterPro; IPR036225; SRP/SRP_N. DR InterPro; IPR000897; SRP54_GTPase_dom. DR InterPro; IPR042101; SRP54_N_sf. DR PANTHER; PTHR43134:SF7; PTHR43134:SF7; 1. DR Pfam; PF00448; SRP54; 1. DR Pfam; PF02881; SRP54_N; 1. DR SMART; SM00382; AAA; 1. DR SMART; SM00962; SRP54; 1. DR SMART; SM00963; SRP54_N; 1. DR SUPFAM; SSF47364; SSF47364; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR00064; ftsY; 1. DR PROSITE; PS00300; SRP54; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00920}; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000280842}; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00920}; KW GTP-binding {ECO:0000256|HAMAP-Rule:MF_00920}; KW Membrane {ECO:0000256|HAMAP-Rule:MF_00920}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00920}; KW Receptor {ECO:0000256|HAMAP-Rule:MF_00920, KW ECO:0000313|EMBL:RMA97310.1}. FT DOMAIN 277 290 SRP54. {ECO:0000259|PROSITE:PS00300}. FT NP_BIND 110 117 GTP. {ECO:0000256|HAMAP-Rule:MF_00920}. FT NP_BIND 192 196 GTP. {ECO:0000256|HAMAP-Rule:MF_00920}. FT NP_BIND 256 259 GTP. {ECO:0000256|HAMAP-Rule:MF_00920}. FT COILED 64 84 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 304 AA; 33255 MW; B32ACC4AA03214B0 CRC64; MFKSMFERIK KGLEKTKNQI SESLYAISFG KKIDESLFEE IEFALLKADV GIDATEEIVE FLRKESKKRK ITEGEQLKEL LKEKLIDILT PCSGQLNLLG EKPDVILFLG INGSGKTTTV GKLAALLKNE GKSVVLAAAD TFRAAAIDQL EVWANRVGAR IVKHQPGADP AAVVFDAVNS AKSRGDDIVL VDTAGRLHTK EHLMKELQKI KRTIQKFSPN QPCETLLVLD GTIGQNSIKQ AQVFKESTDV SGIVITKLDG TAKGGALIPI CQKLQIPIKF IGVGEDIEDL QPFDPKSFVE AIIG //