ID A0A3G6IHV5_MYOGA Unreviewed; 92 AA. AC A0A3G6IHV5; DT 13-FEB-2019, integrated into UniProtKB/TrEMBL. DT 13-FEB-2019, sequence version 1. DT 29-MAY-2024, entry version 9. DE SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AZA04696.1}; DE Flags: Fragment; GN Name=Mygl-IA {ECO:0000313|EMBL:AZA04696.1}; OS Myodes glareolus (Bank vole) (Clethrionomys glareolus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; OC Cricetidae; Arvicolinae; Myodes. OX NCBI_TaxID=447135 {ECO:0000313|EMBL:AZA04696.1}; RN [1] {ECO:0000313|EMBL:AZA04696.1} RP NUCLEOTIDE SEQUENCE. RA Migalska M., Sebastian A., Radwan J.; RT "Major histocompatibility complex class I diversity limits repertoire of T- RT cell receptors."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in the presentation of foreign antigens to the CC immune system. {ECO:0000256|ARBA:ARBA00002297}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single- CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}. CC -!- SIMILARITY: Belongs to the MHC class I family. CC {ECO:0000256|ARBA:ARBA00006909, ECO:0000256|RuleBase:RU004439}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MH018398; AZA04696.1; -; mRNA. DR AlphaFoldDB; A0A3G6IHV5; -. DR GO; GO:0009897; C:external side of plasma membrane; IEA:TreeGrafter. DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter. DR GO; GO:0098553; C:lumenal side of endoplasmic reticulum membrane; IEA:UniProt. DR GO; GO:0042612; C:MHC class I protein complex; IEA:UniProtKB-KW. DR GO; GO:0030670; C:phagocytic vesicle membrane; IEA:UniProt. DR GO; GO:0042605; F:peptide antigen binding; IEA:TreeGrafter. DR GO; GO:0005102; F:signaling receptor binding; IEA:TreeGrafter. DR GO; GO:0002486; P:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; IEA:TreeGrafter. DR GO; GO:0002476; P:antigen processing and presentation of endogenous peptide antigen via MHC class Ib; IEA:TreeGrafter. DR GO; GO:0006955; P:immune response; IEA:TreeGrafter. DR GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:TreeGrafter. DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1. DR InterPro; IPR011161; MHC_I-like_Ag-recog. DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf. DR InterPro; IPR011162; MHC_I/II-like_Ag-recog. DR InterPro; IPR001039; MHC_I_a_a1/a2. DR PANTHER; PTHR16675:SF242; CLASS IB MHC ANTIGEN QA-2-RELATED; 1. DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1. DR Pfam; PF00129; MHC_I; 1. DR PRINTS; PR01638; MHCCLASSI. DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1. PE 2: Evidence at transcript level; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Immunity {ECO:0000256|ARBA:ARBA00022451}; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW MHC I {ECO:0000256|ARBA:ARBA00022451}. FT DOMAIN 1..89 FT /note="MHC class I-like antigen recognition-like" FT /evidence="ECO:0000259|Pfam:PF00129" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AZA04696.1" FT NON_TER 92 FT /evidence="ECO:0000313|EMBL:AZA04696.1" SQ SEQUENCE 92 AA; 10689 MW; E43A86DB16623155 CRC64; GSHTIQMMYG CEVGSDGRLL RGYEQHAYDG RDYIALNEDL TTWTAADTAA QITQRKWEQA GEAERWKAYL EDECVQWLRR YLENGKDALL RT //