ID A0A3G2FGC8_9GAMM Unreviewed; 524 AA. AC A0A3G2FGC8; DT 13-FEB-2019, integrated into UniProtKB/TrEMBL. DT 13-FEB-2019, sequence version 1. DT 03-JUL-2019, entry version 4. DE RecName: Full=Na(+)/H(+) antiporter NhaB {ECO:0000256|HAMAP-Rule:MF_01599, ECO:0000256|SAAS:SAAS00919140}; DE AltName: Full=Sodium/proton antiporter NhaB {ECO:0000256|HAMAP-Rule:MF_01599}; GN Name=nhaB {ECO:0000256|HAMAP-Rule:MF_01599, GN ECO:0000313|EMBL:AYM90619.1}; GN ORFNames=D9980_08485 {ECO:0000313|EMBL:AYM90619.1}; OS Serratia sp. 3ACOL1. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Yersiniaceae; Serratia. OX NCBI_TaxID=2448483 {ECO:0000313|EMBL:AYM90619.1, ECO:0000313|Proteomes:UP000281837}; RN [1] {ECO:0000313|EMBL:AYM90619.1, ECO:0000313|Proteomes:UP000281837} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=3ACOL1 {ECO:0000313|EMBL:AYM90619.1}; RA Bekkelund A.K., Markussen T., Sorum H.; RT "Characterization of cellulolytic bacteria isolated from the larvae of RT long-horned wood boring beetles inhabiting Norwegian Boreal forests."; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Na(+)/H(+) antiporter that extrudes sodium in exchange CC for external protons. {ECO:0000256|HAMAP-Rule:MF_01599, CC ECO:0000256|SAAS:SAAS00919141}. CC -!- SUBCELLULAR LOCATION: Cell inner membrane CC {ECO:0000256|SAAS:SAAS00919154}; Multi-pass membrane protein CC {ECO:0000256|SAAS:SAAS00919154}. Cell membrane {ECO:0000256|HAMAP- CC Rule:MF_01599}; Multi-pass membrane protein {ECO:0000256|HAMAP- CC Rule:MF_01599}. CC -!- SIMILARITY: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter CC family. {ECO:0000256|HAMAP-Rule:MF_01599, CC ECO:0000256|SAAS:SAAS00919142}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation CC of feature annotation. {ECO:0000256|HAMAP-Rule:MF_01599}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP033055; AYM90619.1; -; Genomic_DNA. DR Proteomes; UP000281837; Chromosome. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro. DR HAMAP; MF_01599; NhaB; 1. DR InterPro; IPR004671; Na+/H+_antiporter_NhaB. DR PANTHER; PTHR43302:SF1; PTHR43302:SF1; 1. DR Pfam; PF06450; NhaB; 1. DR TIGRFAMs; TIGR00774; NhaB; 1. PE 3: Inferred from homology; KW Antiport {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919144}; KW Cell inner membrane {ECO:0000256|SAAS:SAAS00919146}; KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919157}; KW Complete proteome {ECO:0000313|Proteomes:UP000281837}; KW Ion transport {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919156}; KW Membrane {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919145}; KW Sodium {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919153}; KW Sodium transport {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919152}; KW Transmembrane {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919149}; KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919148}; KW Transport {ECO:0000256|HAMAP-Rule:MF_01599, KW ECO:0000256|SAAS:SAAS00919150}. FT TRANSMEM 20 39 Helical. {ECO:0000256|HAMAP-Rule: FT MF_01599}. FT TRANSMEM 70 90 Helical. {ECO:0000256|HAMAP-Rule: FT MF_01599}. FT TRANSMEM 96 118 Helical. {ECO:0000256|HAMAP-Rule: FT MF_01599}. FT TRANSMEM 130 156 Helical. {ECO:0000256|HAMAP-Rule: FT MF_01599}. FT TRANSMEM 245 268 Helical. {ECO:0000256|HAMAP-Rule: FT MF_01599}. FT TRANSMEM 299 315 Helical. {ECO:0000256|HAMAP-Rule: FT MF_01599}. FT TRANSMEM 350 368 Helical. {ECO:0000256|HAMAP-Rule: FT MF_01599}. FT TRANSMEM 478 497 Helical. {ECO:0000256|HAMAP-Rule: FT MF_01599}. SQ SEQUENCE 524 AA; 56989 MW; 01AF74E92CC79144 CRC64; MDMTIRSALV KNFLGASPDW YKLAIISFLV INPLVFFLVS PFVAGWLLVI EFIFTLAMAL KCYPLQPGGL LAIEAVLIGM TSPAHVSAEI ASNLEVLLLL VFMVAGIYFM KQLLLFVFTK LLLNIRSKML LSLSFCVAAA LLSAFLDALT VVAVVISVGT GFYSIYHNVA SNQKIDISDD SHLEDADHKQ TLEQFRGFLR SLLMHAGVGT ALGGVMTMVG EPQNLIIAKS AGWGFGEFFL RMTPVTLPVF VCGLLVCLLV ERFAVFGYGT KLPDQVRSVL KEFDRQATAK RSRQEKMKLV VQALIGLWLV IALAFHLAEV GLIGLSVIIL ATSLCGVTDE HAIGKAFQEA LPFTALLTVF FTVVAVIIEQ QLFTPVIHYV LQAPPSSQLS LFYLFNGLLS SVSDNVFVGT VYINEARAAL ADGAISLQQF ELLAVAINTG TNLPSVATPN GQAAFLFLLT SALAPLVRLS YGRMVWMALP YTVVLTLVGL LCVQHTLAPV TDLFTQWQWL MPLPLDATAP IAAH //