ID A0A3D8SHL3_9HELO Unreviewed; 422 AA. AC A0A3D8SHL3; DT 16-JAN-2019, integrated into UniProtKB/TrEMBL. DT 16-JAN-2019, sequence version 1. DT 27-NOV-2024, entry version 19. DE RecName: Full=FAD-binding domain-containing protein {ECO:0000259|Pfam:PF01494}; GN ORFNames=BP6252_02838 {ECO:0000313|EMBL:RDW85248.1}; OS Coleophoma cylindrospora. OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes; OC Helotiales; Dermateaceae; Coleophoma. OX NCBI_TaxID=1849047 {ECO:0000313|EMBL:RDW85248.1, ECO:0000313|Proteomes:UP000256645}; RN [1] {ECO:0000313|EMBL:RDW85248.1, ECO:0000313|Proteomes:UP000256645} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BP6252 {ECO:0000313|EMBL:RDW85248.1, RC ECO:0000313|Proteomes:UP000256645}; RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13; RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J., RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W., RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R., RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J., RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J., RA Xiong C., Yue Q., Zhang X.; RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium, RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains, RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina, RT and Morchella septimelata."; RL IMA Fungus 9:199-223(2018). CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:RDW85248.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; PDLM01000002; RDW85248.1; -; Genomic_DNA. DR AlphaFoldDB; A0A3D8SHL3; -. DR STRING; 1849047.A0A3D8SHL3; -. DR Proteomes; UP000256645; Unassembled WGS sequence. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0071949; F:FAD binding; IEA:InterPro. DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:TreeGrafter. DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1. DR InterPro; IPR002938; FAD-bd. DR InterPro; IPR036188; FAD/NAD-bd_sf. DR InterPro; IPR051104; FAD_monoxygenase. DR PANTHER; PTHR46720; HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED; 1. DR PANTHER; PTHR46720:SF3; HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED; 1. DR Pfam; PF01494; FAD_binding_3; 1. DR PRINTS; PR00420; RNGMNOXGNASE. DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1. DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1. PE 4: Predicted; KW FAD {ECO:0000256|ARBA:ARBA00022827}; KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033}; KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}; KW Reference proteome {ECO:0000313|Proteomes:UP000256645}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 6..27 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 10..368 FT /note="FAD-binding" FT /evidence="ECO:0000259|Pfam:PF01494" SQ SEQUENCE 422 AA; 46603 MW; BFA09D79D0A11F5B CRC64; MGGSSNPLNI AIIGAGIGGL ALAIGLLRQN VPYTLYEAAA EYSTIGAGVG LGPNALRAMD MIDPRFRALY EDISSGNLTP NKNHVMMDAL LIEEGFGKNQ GIDPASYGAD CYDRTSCHRK ALLDIMTGLI PLSTVRFNKR LKSLVQEKDK VIITFEDGEV TEANSVIGCD GVKGATRPVV LGEKYPEKVE ATYSGKYAYR SIIPMKDAVE ILGEHAGDAK MFMGPGVNMT TFPISKGTAC NAVVFKLDDK PWSYQDWTRP VDPEVMFGDF STGVDKRLVK LLEWGKPLQW SIWHHLDTPI YYNGLICLLG DSAHATTPHQ AAGAGQCLED ALILSRLLGK VTSLTQVEPA YKIYDSIRRP RAQRVVRTSH ETGLIYAFRH PDFGTDMRKI VEHLNERFLW LWEHDLHSDV VKAEAEFAKI IN //