ID A0A3D5VHS3_9FIRM Unreviewed; 138 AA. AC A0A3D5VHS3; DT 16-JAN-2019, integrated into UniProtKB/TrEMBL. DT 16-JAN-2019, sequence version 1. DT 08-MAY-2019, entry version 4. DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:HCX79290.1}; GN ORFNames=DG577_07745 {ECO:0000313|EMBL:HCX79290.1}; OS Firmicutes bacterium. OC Bacteria; Firmicutes. OX NCBI_TaxID=1879010 {ECO:0000313|EMBL:HCX79290.1}; RN [1] {ECO:0000313|EMBL:HCX79290.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=UBA10586 {ECO:0000313|EMBL:HCX79290.1}; RX PubMed=30148503; DOI=10.1038/nbt.4229; RA Parks D.H., Chuvochina M., Waite D.W., Rinke C., Skarshewski A., RA Chaumeil P.A., Hugenholtz P.; RT "A standardized bacterial taxonomy based on genome phylogeny RT substantially revises the tree of life."; RL Nat. Biotechnol. 36:996-1004(2018). CC -!- COFACTOR: CC Name=FMN; Xref=ChEBI:CHEBI:58210; CC Evidence={ECO:0000256|SAAS:SAAS00611625}; CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo CC pathway. {ECO:0000256|SAAS:SAAS00586761}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:HCX79290.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DPOK01000154; HCX79290.1; -; Genomic_DNA. DR UniPathway; UPA00070; -. DR GO; GO:0005737; C:cytoplasm; IEA:InterPro. DR GO; GO:0004152; F:dihydroorotate dehydrogenase activity; IEA:InterPro. DR GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro. DR GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway. DR Gene3D; 3.20.20.70; -; 1. DR InterPro; IPR017896; 4Fe4S_Fe-S-bd. DR InterPro; IPR013785; Aldolase_TIM. DR InterPro; IPR005720; Dihydroorotate_DH. DR InterPro; IPR001295; Dihydroorotate_DH_CS. DR Pfam; PF01180; DHO_dh; 1. DR Pfam; PF00037; Fer4; 2. DR PROSITE; PS51379; 4FE4S_FER_2; 2. DR PROSITE; PS00912; DHODEHASE_2; 1. PE 4: Predicted; KW Flavoprotein {ECO:0000256|SAAS:SAAS00243575}; KW FMN {ECO:0000256|SAAS:SAAS00459616}; KW Oxidoreductase {ECO:0000256|SAAS:SAAS00243616}. FT DOMAIN 80 109 4Fe-4S ferredoxin-type. FT {ECO:0000259|PROSITE:PS51379}. FT DOMAIN 110 137 4Fe-4S ferredoxin-type. FT {ECO:0000259|PROSITE:PS51379}. SQ SEQUENCE 138 AA; 15016 MW; E0D1A2ADBF4E1A30 CRC64; MDIPILGVGG IRSGREAVKM IMAGASAVQV CTAAILEGPE VYGKIARQIE QYMEERGIES LAEIQGLAHK SQRQEDLQRW QPAINPELCT ACGRCAQSCV YHAIKVGKYA VVDEERCVGC GLCITRCKFG AITPKFLD //