ID A0A3D3AWM0_ACISP Unreviewed; 271 AA. AC A0A3D3AWM0; DT 16-JAN-2019, integrated into UniProtKB/TrEMBL. DT 16-JAN-2019, sequence version 1. DT 14-DEC-2022, entry version 11. DE RecName: Full=Zinc transporter ZupT {ECO:0000256|HAMAP-Rule:MF_00548}; GN Name=zupT {ECO:0000256|HAMAP-Rule:MF_00548}; GN ORFNames=DHW80_11365 {ECO:0000313|EMBL:HCL60355.1}; OS Acinetobacter sp. OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae; OC Acinetobacter. OX NCBI_TaxID=472 {ECO:0000313|EMBL:HCL60355.1, ECO:0000313|Proteomes:UP000262724}; RN [1] {ECO:0000313|EMBL:HCL60355.1, ECO:0000313|Proteomes:UP000262724} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=UBA8043 {ECO:0000313|EMBL:HCL60355.1}; RX PubMed=30148503; DOI=.1038/nbt.4229; RA Parks D.H., Chuvochina M., Waite D.W., Rinke C., Skarshewski A., RA Chaumeil P.A., Hugenholtz P.; RT "A standardized bacterial taxonomy based on genome phylogeny substantially RT revises the tree of life."; RL Nat. Biotechnol. 36:996-1004(2018). CC -!- FUNCTION: Mediates zinc uptake. May also transport other divalent CC cations. {ECO:0000256|HAMAP-Rule:MF_00548}. CC -!- CATALYTIC ACTIVITY: CC Reaction=Zn(2+)(in) = Zn(2+)(out); Xref=Rhea:RHEA:29351, CC ChEBI:CHEBI:29105; Evidence={ECO:0000256|HAMAP-Rule:MF_00548}; CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00548}; CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00548}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT CC subfamily. {ECO:0000256|ARBA:ARBA00009703, ECO:0000256|HAMAP- CC Rule:MF_00548}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:HCL60355.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DPWU01000308; HCL60355.1; -; Genomic_DNA. DR AlphaFoldDB; A0A3D3AWM0; -. DR Proteomes; UP000262724; Unassembled WGS sequence. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro. DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-UniRule. DR HAMAP; MF_00548; ZupT; 1. DR InterPro; IPR003689; ZIP. DR InterPro; IPR023498; Zn_transptr_ZupT. DR Pfam; PF02535; Zip; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP- KW Rule:MF_00548}; Ion transport {ECO:0000256|HAMAP-Rule:MF_00548}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00548}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP- KW Rule:MF_00548}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP- KW Rule:MF_00548}; KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00548}; KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|HAMAP-Rule:MF_00548}; KW Zinc transport {ECO:0000256|ARBA:ARBA00022906, ECO:0000256|HAMAP- KW Rule:MF_00548}. FT TRANSMEM 12..35 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00548" FT TRANSMEM 42..59 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00548" FT TRANSMEM 79..101 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00548" FT TRANSMEM 121..137 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00548" FT TRANSMEM 185..208 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00548" FT TRANSMEM 214..237 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00548" FT TRANSMEM 249..270 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00548" SQ SEQUENCE 271 AA; 28496 MW; 7EC8948BC5C5620B CRC64; MGIAPVTDAQ VYTAFAVTFL AGLATLVGGG LVLFLKKPNY RVLAFGLAFA AGAMIYVSLT EILNKSISSF SLAFDEKSGF AYGTFAFLLG VVLVLLLDRF VPNPHETIEA QSKQDLSQPQ LLRTGLLALF AISAHNLPEG LATFFATLES PALGAPLAVA IAIHNIPEGV AIALPVYGAT GRKDYALVAS LVSGLAEPLG AALGYFILAP YMSHTIYGMV FGIIGGVMVY LALDELLPTA KRFSKGHETV YGLVSGMAAL ATSLVIFKFV Q //