ID A0A3D2UWL8_9BACT Unreviewed; 404 AA. AC A0A3D2UWL8; DT 16-JAN-2019, integrated into UniProtKB/TrEMBL. DT 16-JAN-2019, sequence version 1. DT 03-MAY-2023, entry version 15. DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:HCK68723.1}; GN ORFNames=DD452_09800 {ECO:0000313|EMBL:HBP12221.1}, DHW17_05525 GN {ECO:0000313|EMBL:HCK68723.1}; OS Nitrospina sp. OC Bacteria; Nitrospinae/Tectomicrobia group; Nitrospinae; Nitrospinia; OC Nitrospinales; Nitrospinaceae; Nitrospina. OX NCBI_TaxID=2024844 {ECO:0000313|EMBL:HCK68723.1, ECO:0000313|Proteomes:UP000262184}; RN [1] {ECO:0000313|Proteomes:UP000262184, ECO:0000313|Proteomes:UP000264013} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=UBA8107 {ECO:0000313|EMBL:HBP12221.1}, and UBA9663 RC {ECO:0000313|EMBL:HCK68723.1}; RX PubMed=30148503; DOI=.1038/nbt.4229; RA Parks D.H., Chuvochina M., Waite D.W., Rinke C., Skarshewski A., RA Chaumeil P.A., Hugenholtz P.; RT "A standardized bacterial taxonomy based on genome phylogeny substantially RT revises the tree of life."; RL Nat. Biotechnol. 36:996-1004(2018). CC -!- COFACTOR: CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; CC Evidence={ECO:0000256|ARBA:ARBA00001966}; CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:HCK68723.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DODH01000290; HBP12221.1; -; Genomic_DNA. DR EMBL; DPVJ01000150; HCK68723.1; -; Genomic_DNA. DR AlphaFoldDB; A0A3D2UWL8; -. DR EnsemblBacteria; HCK68723; HCK68723; DHW17_05525. DR Proteomes; UP000262184; Unassembled WGS sequence. DR Proteomes; UP000264013; Unassembled WGS sequence. DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro. DR GO; GO:0003824; F:catalytic activity; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR CDD; cd01335; Radical_SAM; 1. DR CDD; cd21109; SPASM; 1. DR Gene3D; 3.20.20.70; Aldolase class I; 1. DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom. DR InterPro; IPR013785; Aldolase_TIM. DR InterPro; IPR000385; MoaA_NifB_PqqE_Fe-S-bd_CS. DR InterPro; IPR007197; rSAM. DR PANTHER; PTHR11228:SF7; ANTILISTERIAL BACTERIOCIN SUBTILOSIN BIOSYNTHESIS PROTEIN ALBA; 1. DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1. DR Pfam; PF13394; Fer4_14; 1. DR Pfam; PF04055; Radical_SAM; 1. DR Pfam; PF13186; SPASM; 1. DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1. DR SFLD; SFLDS00029; Radical_SAM; 1. DR SUPFAM; SSF102114; Radical SAM enzymes; 1. DR PROSITE; PS01305; MOAA_NIFB_PQQE; 1. DR PROSITE; PS51918; RADICAL_SAM; 1. PE 4: Predicted; KW Iron {ECO:0000256|ARBA:ARBA00023004}; KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}. FT DOMAIN 26..271 FT /note="Radical SAM core" FT /evidence="ECO:0000259|PROSITE:PS51918" SQ SEQUENCE 404 AA; 46327 MW; 59144D91B073139E CRC64; MDFKVLQKIL PRIYSFLPFY LAPRFALPPV QAFFEVTYRC NLRCDMCHYL EIIEETESQK TYKNEMSSEE VKKAISRLPR FSLITFTGGE AFMKTDFMEI LEFATRKHKV HIITNGTTLS DKVVEDLMRL RLKSVWGSGL FYMGVSIEGG EALHDGITTV PGSFKKTTEG LERLIARRKE LKSRFPLIHL TCVIKRENVR DLVPLYEYAN KLGVDVSNFV LNSPATYWHG KDYDQDDHLQ RPTAPVEEIA PEILQEQLEL LQEKSKGYRT RLRFSPNYIT VDEIVRYYSN KSSYQDYRCY IPWTKVAISA YGDVFSCPHY RVGNVNSGSD SSAWQTERIQ GFREKLKAEG IFPGCLGCCQ SEYIGPSPLM TPVVSKNPAR KVKFLKARES TCSVPTFNRE GPGA //