ID A0A3D1NBD2_9DELT Unreviewed; 471 AA. AC A0A3D1NBD2; DT 16-JAN-2019, integrated into UniProtKB/TrEMBL. DT 16-JAN-2019, sequence version 1. DT 05-JUN-2019, entry version 5. DE RecName: Full=Diadenylate cyclase {ECO:0000256|SAAS:SAAS00772208}; DE EC=2.7.7.85 {ECO:0000256|SAAS:SAAS00772190}; GN ORFNames=DEU72_00225 {ECO:0000313|EMBL:HCF04658.1}; OS Desulfomicrobiaceae bacterium. OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales; OC Desulfomicrobiaceae; unclassified Desulfomicrobiaceae. OX NCBI_TaxID=2053547 {ECO:0000313|EMBL:HCF04658.1}; RN [1] {ECO:0000313|EMBL:HCF04658.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=UBA12183 {ECO:0000313|EMBL:HCF04658.1}; RX PubMed=30148503; DOI=.1038/nbt.4229; RA Parks D.H., Chuvochina M., Waite D.W., Rinke C., Skarshewski A., RA Chaumeil P.A., Hugenholtz P.; RT "A standardized bacterial taxonomy based on genome phylogeny RT substantially revises the tree of life."; RL Nat. Biotechnol. 36:996-1004(2018). CC -!- CATALYTIC ACTIVITY: CC Reaction=2 ATP = c-di-AMP + 2 diphosphate; Xref=Rhea:RHEA:35655, CC ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:71500; CC EC=2.7.7.85; Evidence={ECO:0000256|SAAS:SAAS01115408}; CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:HCF04658.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DPEO01000003; HCF04658.1; -; Genomic_DNA. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW. DR InterPro; IPR036888; DNA_integrity_DisA_N_sf. DR InterPro; IPR003390; DNA_integrity_scan_DisA_N. DR Pfam; PF02457; DisA_N; 1. DR SUPFAM; SSF143597; SSF143597; 1. DR PROSITE; PS51794; DAC; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|SAAS:SAAS00772210}; KW DNA-binding {ECO:0000313|EMBL:HCF04658.1}; KW Nucleotide-binding {ECO:0000256|SAAS:SAAS00772222}; KW Nucleotidyltransferase {ECO:0000256|SAAS:SAAS00772249}; KW Transferase {ECO:0000256|SAAS:SAAS00772224}. FT DOMAIN 300 451 DAC. {ECO:0000259|PROSITE:PS51794}. SQ SEQUENCE 471 AA; 52309 MW; 4BC357ADE5416829 CRC64; MSTPLLFRKT LFHICDGLGA GLSRFSGPSR VAVVYALEDT GPVFIHDPQD LLREHEPKIR EIFSRFPPPL CPAGPAYDGF IPCADVQLSG IISFGARSAP LPLQMWFTDH HPDICSVLPT QRWLEQACRL MVQSMESRAC TVENAGFILH DFALHAVRDA IVDERSRSIM DSRLRVYTVL AAILDLSKAR EEGRLPVGEM AFVEPDLVDT IHYMAKLDPH ERPLLQDTKH VRKLLQAVEG TRHRLVCDGT HIIGIGAGRL PDYSIGAEFL GSYGFISLQE EKICSFADGS LHSSTREPIL VALEETLVEM RWPAHHIYGI MHMVLEIVKS AQERRHGCAL ILDYGTPLAH TSGQRLTSAL NLRRLAELDL AKTLARVDGA LHIDIRTLRL VAFATLMDGK AVPGESRARG ARYNSALRFS AEHPDLFVVV VSADRPISII QHGAELSTRC EWQPQGRDVG SPLPLEQWAS P //