ID A0A396MFA8_9CLOT Unreviewed; 227 AA. AC A0A396MFA8; DT 05-DEC-2018, integrated into UniProtKB/TrEMBL. DT 05-DEC-2018, sequence version 1. DT 13-FEB-2019, entry version 3. DE RecName: Full=Ribulose-phosphate 3-epimerase {ECO:0000256|PIRNR:PIRNR001461}; DE EC=5.1.3.1 {ECO:0000256|PIRNR:PIRNR001461}; GN Name=rpe {ECO:0000313|EMBL:RHS31415.1}; GN ORFNames=DWV55_12840 {ECO:0000313|EMBL:RHS31415.1}; OS Butyricicoccus sp. AF10-3. OC Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; OC Butyricicoccus. OX NCBI_TaxID=2292196 {ECO:0000313|EMBL:RHS31415.1, ECO:0000313|Proteomes:UP000266580}; RN [1] {ECO:0000313|EMBL:RHS31415.1, ECO:0000313|Proteomes:UP000266580} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AF10-3 {ECO:0000313|EMBL:RHS31415.1, RC ECO:0000313|Proteomes:UP000266580}; RA Zou Y., Xue W., Luo G.; RT "A genome reference for cultivated species of the human gut RT microbiota."; RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=D-ribulose 5-phosphate = D-xylulose 5-phosphate; CC Xref=Rhea:RHEA:13677, ChEBI:CHEBI:57737, ChEBI:CHEBI:58121; CC EC=5.1.3.1; Evidence={ECO:0000256|PIRNR:PIRNR001461}; CC -!- COFACTOR: CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; CC Evidence={ECO:0000256|PIRSR:PIRSR001461-2}; CC Note=Binds 1 divalent metal cation per subunit. CC {ECO:0000256|PIRSR:PIRSR001461-2}; CC -!- SIMILARITY: Belongs to the ribulose-phosphate 3-epimerase family. CC {ECO:0000256|PIRNR:PIRNR001461}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:RHS31415.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QUHS01000048; RHS31415.1; -; Genomic_DNA. DR Proteomes; UP000266580; Unassembled WGS sequence. DR GO; GO:0004750; F:ribulose-phosphate 3-epimerase activity; IEA:UniProtKB-EC. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. DR CDD; cd00429; RPE; 1. DR Gene3D; 3.20.20.70; -; 1. DR InterPro; IPR013785; Aldolase_TIM. DR InterPro; IPR026019; Ribul_P_3_epim. DR InterPro; IPR000056; Ribul_P_3_epim-like. DR InterPro; IPR011060; RibuloseP-bd_barrel. DR PANTHER; PTHR11749; PTHR11749; 1. DR Pfam; PF00834; Ribul_P_3_epim; 1. DR PIRSF; PIRSF001461; RPE; 1. DR SUPFAM; SSF51366; SSF51366; 1. DR TIGRFAMs; TIGR01163; rpe; 1. DR PROSITE; PS01085; RIBUL_P_3_EPIMER_1; 1. DR PROSITE; PS01086; RIBUL_P_3_EPIMER_2; 1. PE 3: Inferred from homology; KW Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR001461}; KW Cobalt {ECO:0000256|PIRSR:PIRSR001461-2}; KW Complete proteome {ECO:0000313|Proteomes:UP000266580}; KW Isomerase {ECO:0000256|PIRNR:PIRNR001461, KW ECO:0000313|EMBL:RHS31415.1}; KW Manganese {ECO:0000256|PIRSR:PIRSR001461-2}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR001461-2}; KW Zinc {ECO:0000256|PIRSR:PIRSR001461-2}. FT REGION 142 145 Substrate binding. {ECO:0000256|PIRSR: FT PIRSR001461-3}. FT REGION 197 198 Substrate binding. {ECO:0000256|PIRSR: FT PIRSR001461-3}. FT ACT_SITE 35 35 Proton acceptor. {ECO:0000256|PIRSR: FT PIRSR001461-1}. FT ACT_SITE 175 175 Proton donor. {ECO:0000256|PIRSR: FT PIRSR001461-1}. FT METAL 33 33 Divalent metal cation. FT {ECO:0000256|PIRSR:PIRSR001461-2}. FT METAL 35 35 Divalent metal cation. FT {ECO:0000256|PIRSR:PIRSR001461-2}. FT METAL 66 66 Divalent metal cation. FT {ECO:0000256|PIRSR:PIRSR001461-2}. FT METAL 175 175 Divalent metal cation. FT {ECO:0000256|PIRSR:PIRSR001461-2}. FT BINDING 8 8 Substrate. {ECO:0000256|PIRSR: FT PIRSR001461-3}. FT BINDING 66 66 Substrate. {ECO:0000256|PIRSR: FT PIRSR001461-3}. FT BINDING 177 177 Substrate; via amide nitrogen. FT {ECO:0000256|PIRSR:PIRSR001461-3}. SQ SEQUENCE 227 AA; 24201 MW; 1EC8876942A547CA CRC64; MEIKLSPSIL SADFANLARD IKIATDAGAE YVHVDVMDGH FVPNITIGAP VVKALRKATD KVLDVHLMIS DPDQYLDDFI KAGSDIITVH YESNGDTLEQ LKKIRAAGVK AACVIKPKTP AEVLFPLLPY CDMVLIMTVE PGFGGQGFIP ECMDKIKAVR AEIQKNGYKC ELEIDGGAKL NNTADIVAAG ADVIVAGSAV FGGDIAANVK GFHEVFKEGA AKAAWSK //