ID A0A384NKS6_HUMAN Unreviewed; 501 AA. AC A0A384NKS6; DT 05-DEC-2018, integrated into UniProtKB/TrEMBL. DT 05-DEC-2018, sequence version 1. DT 11-DEC-2019, entry version 6. DE RecName: Full=Clusterin {ECO:0000256|RuleBase:RU000629}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ADO22253.1}; RN [1] {ECO:0000313|EMBL:ADO22253.1} RP NUCLEOTIDE SEQUENCE. RA Hoernsten L., Su C., Osbourn A.E., Hellman U., Wernstedt C., Oliw E.H.; RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the clusterin family. CC {ECO:0000256|RuleBase:RU000629}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GQ891391; ADO22253.1; -; mRNA. DR RefSeq; XP_006716347.1; XM_006716284.2. DR GeneID; 1191; -. DR CTD; 1191; -. DR InterPro; IPR016016; Clusterin. DR InterPro; IPR000753; Clusterin-like. DR InterPro; IPR016015; Clusterin_C. DR InterPro; IPR033986; Clusterin_CS. DR InterPro; IPR016014; Clusterin_N. DR PANTHER; PTHR10970; PTHR10970; 1. DR PANTHER; PTHR10970:SF1; PTHR10970:SF1; 1. DR Pfam; PF01093; Clusterin; 1. DR SMART; SM00035; CLa; 1. DR SMART; SM00030; CLb; 1. DR PROSITE; PS00492; CLUSTERIN_1; 1. DR PROSITE; PS00493; CLUSTERIN_2; 1. PE 2: Evidence at transcript level; KW Coiled coil {ECO:0000256|SAM:Coils}. FT DOMAIN 75..279 FT /note="CLb" FT /evidence="ECO:0000259|SMART:SM00030" FT DOMAIN 280..495 FT /note="CLa" FT /evidence="ECO:0000259|SMART:SM00035" FT REGION 1..39 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 105..146 FT /evidence="ECO:0000256|SAM:Coils" FT COILED 372..399 FT /evidence="ECO:0000256|SAM:Coils" FT COMPBIAS 1..26 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 501 AA; 57833 MW; 1941842E61CD3464 CRC64; MQVCSQPQRG CVREQSAINT APPSAHNAAS PGGARGHRVP LTEACKDSRI GGMMKTLLLF VGLLLTWESG QVLGDQTVSD NELQEMSNQG SKYVNKEIQN AVNGVKQIKT LIEKTNEERK TLLSNLEEAK KKKEDALNET RESETKLKEL PGVCNETMMA LWEECKPCLK QTCMKFYARV CRSGSGLVGR QLEEFLNQSS PFYFWMNGDR IDSLLENDRQ QTHMLDVMQD HFSRASSIID ELFQDRFFTR EPQDTYHYLP FSLPHRRPHF FFPKSRIVRS LMPFSPYEPL NFHAMFQPFL EMIHEAQQAM DIHFHSPAFQ HPPTEFIREG DDDRTVCREI RHNSTGCLRM KDQCDKCREI LSVDCSTNNP SQAKLRRELD ESLQVAERLT RKYNELLKSY QWKMLNTSSL LEQLNEQFNW VSRLANLTQG EDQYYLRVTT VASHTSDSDV PSGVTEVVVK LFDSDPITVT VPVEVSRKNP KFMETVAEKA LQEYRKKHRE E //