ID A0A384MDQ7_HUMAN Unreviewed; 418 AA. AC A0A384MDQ7; DT 05-DEC-2018, integrated into UniProtKB/TrEMBL. DT 05-DEC-2018, sequence version 1. DT 24-JAN-2024, entry version 13. DE SubName: Full=Epididymis secretory sperm binding protein {ECO:0000313|EMBL:ADO22266.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ADO22266.1}; RN [1] {ECO:0000313|EMBL:ADO22266.1} RP NUCLEOTIDE SEQUENCE. RA Hoernsten L., Su C., Osbourn A.E., Hellman U., Wernstedt C., Oliw E.H.; RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the serpin family. CC {ECO:0000256|ARBA:ARBA00009500, ECO:0000256|RuleBase:RU000411}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GQ891404; ADO22266.1; -; mRNA. DR AlphaFoldDB; A0A384MDQ7; -. DR SMR; A0A384MDQ7; -. DR PeptideAtlas; A0A384MDQ7; -. DR GO; GO:0005615; C:extracellular space; IEA:InterPro. DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro. DR CDD; cd02056; serpinA1_A1AT; 1. DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1. DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1. DR Gene3D; 2.10.310.10; Serpins superfamily; 1. DR InterPro; IPR023795; Serpin_CS. DR InterPro; IPR023796; Serpin_dom. DR InterPro; IPR000215; Serpin_fam. DR InterPro; IPR036186; Serpin_sf. DR InterPro; IPR042178; Serpin_sf_1. DR InterPro; IPR042185; Serpin_sf_2. DR PANTHER; PTHR11461:SF165; ALPHA-1-ANTITRYPSIN; 1. DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1. DR Pfam; PF00079; Serpin; 1. DR SMART; SM00093; SERPIN; 1. DR SUPFAM; SSF56574; Serpins; 1. DR PROSITE; PS00284; SERPIN; 1. PE 2: Evidence at transcript level; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690}; KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900}; KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}. FT SIGNAL 1..24 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 25..418 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5017231997" FT DOMAIN 59..415 FT /note="Serpin" FT /evidence="ECO:0000259|SMART:SM00093" SQ SEQUENCE 418 AA; 46723 MW; 70165484573B7F16 CRC64; MPSSVSWGIL LLAGLCCLVP VSLAEDPQGD AAQKTDTSHH DQDHPTFNKI TPNLAEFAFS LYRQLAHQSN STNIFFSPVS IATAFAMLSL GTKADTHDEI LEGLNFNLTE IPEAQIHEGF QELLRTLNQP DSQLQLTTGN GLFLSEGLKL VDKFLEDVKK LYHSEAFTVN FGDTEEAKKQ INDYVEKGTQ GKIVDLVKEL DRDTVFALVN YIFFKGKWER PFEVKDTEEE DFHVDQVTTV KVPMMKRLGM FNIQHCKKLS SWVLLMKYLG NATAIFFLPD EGKLQHLENE LTHDIITKFL ENEDRRSASL HLPKLSITGT YDLKSVLGQL GITKVFSNGA DLSGVTEEAP LKLSKAVHKA VLTIDEKGTE AAGAMFLEAI PMSIPPEVKF NKPFVFLMID QNTKSPLFMG KVVNPTQK //