ID A0A380G394_STAIN Unreviewed; 464 AA. AC A0A380G394; DT 07-NOV-2018, integrated into UniProtKB/TrEMBL. DT 07-NOV-2018, sequence version 1. DT 13-FEB-2019, entry version 4. DE SubName: Full=Transporter protein {ECO:0000313|EMBL:SUM45619.1}; GN Name=emrB_1 {ECO:0000313|EMBL:SUM45619.1}; GN ORFNames=NCTC11048_00606 {ECO:0000313|EMBL:SUM45619.1}; OS Staphylococcus intermedius NCTC 11048. OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; OC Staphylococcus. OX NCBI_TaxID=1141106 {ECO:0000313|EMBL:SUM45619.1, ECO:0000313|Proteomes:UP000255549}; RN [1] {ECO:0000313|EMBL:SUM45619.1, ECO:0000313|Proteomes:UP000255549} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NCTC 11048 {ECO:0000313|Proteomes:UP000255549}; RG Pathogen Informatics; RA Doyle S.; RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the major facilitator superfamily. CC {ECO:0000256|SAAS:SAAS00769108}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; UHDP01000003; SUM45619.1; -; Genomic_DNA. DR RefSeq; WP_019168910.1; NZ_UHDP01000003.1. DR Proteomes; UP000255549; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro. DR CDD; cd06174; MFS; 1. DR InterPro; IPR004638; Drug-R_transpt_efflux_EmrB. DR InterPro; IPR011701; MFS. DR InterPro; IPR020846; MFS_dom. DR InterPro; IPR036259; MFS_trans_sf. DR Pfam; PF07690; MFS_1; 1. DR SUPFAM; SSF103473; SSF103473; 1. DR TIGRFAMs; TIGR00711; efflux_EmrB; 1. DR PROSITE; PS50850; MFS; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|SAAS:SAAS00769078}; KW Complete proteome {ECO:0000313|Proteomes:UP000255549}; KW Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|SAAS:SAAS00769091, KW ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00769070, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}. FT TRANSMEM 12 34 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 54 73 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 82 105 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 111 132 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 139 162 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 168 188 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 200 220 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 232 249 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 269 293 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 305 322 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 334 353 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 359 385 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 406 428 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 440 459 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 16 464 MFS. {ECO:0000259|PROSITE:PS50850}. SQ SEQUENCE 464 AA; 50876 MW; 11806B8AEEFC0CB5 CRC64; MSGSTYHHSI QQHLPAIVIM ISGAFIAVLN QTLFSTVLPE IMADFQLTSS EAQWVTTIFM LVNGIMIPVT AYLSQRFTLR RLFFTALTLF LIGSLLGMLA PNYIFVLVGR AIQAMGAGIL MPLTQTFLFL VFPIEKRGMA MGLFGLVIGF APAIGPTASG WFVNLFNWRY LFLIILVITM IVLILGIFKM TNATELSHPS LDILSVILST LGFGGLLFGF SLAGQYGWGN PLSYVTIIVA LIILTLFVFR QLRLESPMLE MRVFLHRSFT VPIALVVLMF LIFIGTMTML PIYMQSMRGM SPLQSGLVLL PGGLVMGLLA PMNGRLYDNI GGRILAVTGM SFIFIGTVMI SFLNETSPVW YIILSFVILT FGNSGIMVPM TTEAMNALPK SLIPHGTAMN NTLRQISAAI GTGLLVTVMS QIAMAHGGDQ VMRNIFGLQW TYRIVALIVV FGLLVATRVS KKPT //