ID A0A358GHM9_PAESP Unreviewed; 575 AA. AC A0A358GHM9; DT 07-NOV-2018, integrated into UniProtKB/TrEMBL. DT 07-NOV-2018, sequence version 1. DT 05-DEC-2018, entry version 2. DE SubName: Full=Ubiquinone-dependent pyruvate dehydrogenase {ECO:0000313|EMBL:HBU82368.1}; GN ORFNames=DEF35_12105 {ECO:0000313|EMBL:HBU82368.1}; OS Paenibacillus sp. OC Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae; OC Paenibacillus. OX NCBI_TaxID=58172 {ECO:0000313|EMBL:HBU82368.1}; RN [1] {ECO:0000313|EMBL:HBU82368.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=UBA10718 {ECO:0000313|EMBL:HBU82368.1}; RX PubMed=30148503; RA Parks D.H., Chuvochina M., Waite D.W., Rinke C., Skarshewski A., RA Chaumeil P.A., Hugenholtz P.; RT "A standardized bacterial taxonomy based on genome phylogeny RT substantially revises the tree of life."; RL Nat. Biotechnol. 0:0-0(2018). CC -!- SIMILARITY: Belongs to the TPP enzyme family. CC {ECO:0000256|RuleBase:RU362132}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:HBU82368.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DOOE01000018; HBU82368.1; -; Genomic_DNA. DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom. DR InterPro; IPR029061; THDP-binding. DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom. DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom. DR InterPro; IPR000399; TPP-bd_CS. DR InterPro; IPR011766; TPP_enzyme-bd_C. DR Pfam; PF02775; TPP_enzyme_C; 1. DR Pfam; PF00205; TPP_enzyme_M; 1. DR Pfam; PF02776; TPP_enzyme_N; 1. DR SUPFAM; SSF52467; SSF52467; 1. DR SUPFAM; SSF52518; SSF52518; 2. DR PROSITE; PS00187; TPP_ENZYMES; 1. PE 3: Inferred from homology; KW Pyruvate {ECO:0000313|EMBL:HBU82368.1}; KW Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132}; KW Ubiquinone {ECO:0000313|EMBL:HBU82368.1}. FT DOMAIN 4 169 TPP_enzyme_N. {ECO:0000259|Pfam:PF02776}. FT DOMAIN 193 320 TPP_enzyme_M. {ECO:0000259|Pfam:PF00205}. FT DOMAIN 382 528 TPP_enzyme_C. {ECO:0000259|Pfam:PF02775}. SQ SEQUENCE 575 AA; 62614 MW; 99CDB7A34000433A CRC64; MKKTIADVLV EALLNAGIKR IYGIVGDSLN AVLDSIRRSG KIEWIHVRHE EVAAFAAGAD AQVSGSIAVC AGSSGPGNMH LINGLYDCHR NRVPVLAIAA HIPSDEIGSE YFQATHPEYL FQECSHYCEV ITTAKQMPRS FTMAMQTAVA RSGVSVIILP GDVAALEAAD LPVPEHVYHP THPVVHPSEP ELRKLAEFLN QGKKITLLCG AGCAGAREPL MQLCDRLKSP MVIALRGKEY LEYDNPYSVG LTGLIGYSSG YHAMMDCDVL LMLGTDFPYR QFFPEDAVVV QVDIQSSHLG RRTKLDYGVC GDVKATIEML LPYLTEEHSD KHLHKSVERY EKVRKELDEL AVGKPGKMPI HPQYLTKVIS DAAAENAIFT CDVGTPTVWA ARYIEMSRNR RLLGSFSHGT MANALPQAIG AQVSDPGRQV ISLSGDGGIA MLMGDLLTLK QHNLPIKVVV FNNGALGFVE LEMKAAGLLE SGTELVNPNF AMVAQAMGLE GIRVEDPADL EGAVERALLH DGPVLIDVVV NRQELSLPPK INIKQAEGFT LWMMKAVLNG RGDELIELAK TNLLR //