ID A0A355VGS7_9BACT Unreviewed; 343 AA. AC A0A355VGS7; DT 07-NOV-2018, integrated into UniProtKB/TrEMBL. DT 07-NOV-2018, sequence version 1. DT 31-JUL-2019, entry version 6. DE RecName: Full=Cell shape-determining protein MreB {ECO:0000256|HAMAP-Rule:MF_02207}; GN Name=mreB {ECO:0000256|HAMAP-Rule:MF_02207}; GN ORFNames=DD422_06120 {ECO:0000313|EMBL:HBN17608.1}; OS Akkermansia sp. OC Bacteria; Verrucomicrobia; Verrucomicrobiae; Verrucomicrobiales; OC Akkermansiaceae; Akkermansia. OX NCBI_TaxID=1872421 {ECO:0000313|EMBL:HBN17608.1}; RN [1] {ECO:0000313|EMBL:HBN17608.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=UBA11944 {ECO:0000313|EMBL:HBN17608.1}; RX PubMed=30148503; DOI=.1038/nbt.4229; RA Parks D.H., Chuvochina M., Waite D.W., Rinke C., Skarshewski A., RA Chaumeil P.A., Hugenholtz P.; RT "A standardized bacterial taxonomy based on genome phylogeny RT substantially revises the tree of life."; RL Nat. Biotechnol. 36:996-1004(2018). CC -!- FUNCTION: Forms membrane-associated dynamic filaments that are CC essential for cell shape determination. Acts by regulating cell CC wall synthesis and cell elongation, and thus cell shape. A CC feedback loop between cell geometry and MreB localization may CC maintain elongated cell shape by targeting cell wall growth to CC regions of negative cell wall curvature. {ECO:0000256|HAMAP- CC Rule:MF_02207}. CC -!- SUBUNIT: Forms polymers. {ECO:0000256|HAMAP-Rule:MF_02207}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02207}. CC Note=Membrane-associated. {ECO:0000256|HAMAP-Rule:MF_02207}. CC -!- SIMILARITY: Belongs to the FtsA/MreB family. {ECO:0000256|HAMAP- CC Rule:MF_02207}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:HBN17608.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DOBZ01000136; HBN17608.1; -; Genomic_DNA. DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro. DR CDD; cd10225; MreB_like; 1. DR HAMAP; MF_02207; MreB; 1. DR InterPro; IPR004753; MreB. DR PANTHER; PTHR42749; PTHR42749; 1. DR Pfam; PF06723; MreB_Mbl; 1. DR PRINTS; PR01652; SHAPEPROTEIN. DR TIGRFAMs; TIGR00904; mreB; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_02207}; KW Cell shape {ECO:0000256|HAMAP-Rule:MF_02207}; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02207}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_02207}. FT NP_BIND 22 24 ATP. {ECO:0000256|HAMAP-Rule:MF_02207}. FT NP_BIND 164 166 ATP. {ECO:0000256|HAMAP-Rule:MF_02207}. FT NP_BIND 212 215 ATP. {ECO:0000256|HAMAP-Rule:MF_02207}. FT NP_BIND 292 295 ATP. {ECO:0000256|HAMAP-Rule:MF_02207}. SQ SEQUENCE 343 AA; 37013 MW; 55193B84952A9F36 CRC64; MSSFFQKIVK LFSYDIGIDL GTANTLVNVK DQGIVLREPS VVAVKGDKVL AVGDEAKRML GRTPGSVTAI RPLKDGVIAD FYITEEMLRY FIKKATARYY LIKPRVLIAI PSGITEVERR AVKESAEAAG ARRVHLIEEP MAAAIGVGLP VQEAAGNMIV DIGGGTTEVA LISLSGIVYS RSVRCAGDEL DDAIISYMRR TYNLMVGERT AEDIKIRIGS AYPLPQELSI EVKGRDLVAG LPKTVTIRSE EVREALTEQL NTIVDAVRTT LERCPPELAA DLVDRGIVLA GGGALLRGLD QLLHDQTGLP IHIAEDPLSA VAEGTGKALQ ELDFFTNVTD AED //