ID A0A348XPB3_THESC Unreviewed; 414 AA.
AC A0A348XPB3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 05-JUN-2019, entry version 6.
DE RecName: Full=Cell division protein FtsA {ECO:0000256|HAMAP-Rule:MF_02033, ECO:0000256|PIRNR:PIRNR003101};
GN Name=ftsA {ECO:0000256|HAMAP-Rule:MF_02033,
GN ECO:0000313|EMBL:HAR68625.1};
GN ORFNames=CSW14_14160 {ECO:0000313|EMBL:RTI47290.1}, CSW23_07345
GN {ECO:0000313|EMBL:RTI16403.1}, CSW27_01555
GN {ECO:0000313|EMBL:RTI17407.1}, CSW33_12175
GN {ECO:0000313|EMBL:RTH29521.1}, CSW37_13380
GN {ECO:0000313|EMBL:RTH31823.1}, CSW38_00250
GN {ECO:0000313|EMBL:RTH28787.1}, CSW40_11295
GN {ECO:0000313|EMBL:RTH22247.1}, CSW41_12415
GN {ECO:0000313|EMBL:RTH14351.1}, CSW45_02115
GN {ECO:0000313|EMBL:RTH06179.1}, CSW47_10035
GN {ECO:0000313|EMBL:RTH02744.1}, CSW50_04820
GN {ECO:0000313|EMBL:RTH03638.1}, DCR99_02720
GN {ECO:0000313|EMBL:HAR68625.1};
OS Thermus scotoductus.
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae;
OC Thermus.
OX NCBI_TaxID=37636 {ECO:0000313|EMBL:HAR68625.1};
RN [1] {ECO:0000313|Proteomes:UP000286712, ECO:0000313|Proteomes:UP000286734, ECO:0000313|Proteomes:UP000286910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10_S10 {ECO:0000313|EMBL:RTI16403.1,
RC ECO:0000313|Proteomes:UP000288073}, 14_S14
RC {ECO:0000313|EMBL:RTI17407.1, ECO:0000313|Proteomes:UP000287155}, 1_S1
RC {ECO:0000313|EMBL:RTI47290.1, ECO:0000313|Proteomes:UP000287467},
RC 20_S20 {ECO:0000313|EMBL:RTH29521.1,
RC ECO:0000313|Proteomes:UP000286928}, 24_S24
RC {ECO:0000313|EMBL:RTH31823.1, ECO:0000313|Proteomes:UP000288051},
RC 25_S25 {ECO:0000313|EMBL:RTH28787.1,
RC ECO:0000313|Proteomes:UP000287306}, 27_S27
RC {ECO:0000313|EMBL:RTH22247.1, ECO:0000313|Proteomes:UP000286712},
RC 28_S28 {ECO:0000313|EMBL:RTH14351.1,
RC ECO:0000313|Proteomes:UP000287439}, 32_S32
RC {ECO:0000313|EMBL:RTH06179.1, ECO:0000313|Proteomes:UP000286910},
RC 34_S34 {ECO:0000313|EMBL:RTH02744.1,
RC ECO:0000313|Proteomes:UP000286734}, and 38_S38
RC {ECO:0000313|EMBL:RTH03638.1, ECO:0000313|Proteomes:UP000288082};
RX PubMed=30536130;
RA Wilpiszeski R.L., Zhang Z., House C.H.;
RT "Biogeography of thermophiles and predominance of Thermus scotoductus
RT in domestic water heaters.";
RL Extremophiles 0:0-0(2018).
RN [2] {ECO:0000313|EMBL:HAR68625.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UBA10524 {ECO:0000313|EMBL:HAR68625.1};
RX PubMed=30148503; DOI=.1038/nbt.4229;
RA Parks D.H., Chuvochina M., Waite D.W., Rinke C., Skarshewski A.,
RA Chaumeil P.A., Hugenholtz P.;
RT "A standardized bacterial taxonomy based on genome phylogeny
RT substantially revises the tree of life.";
RL Nat. Biotechnol. 36:996-1004(2018).
CC -!- FUNCTION: Cell division protein that is involved in the assembly
CC of the Z ring. May serve as a membrane anchor for the Z ring.
CC {ECO:0000256|HAMAP-Rule:MF_02033, ECO:0000256|PIRNR:PIRNR003101}.
CC -!- SUBUNIT: Interacts with FtsZ. {ECO:0000256|PIRNR:PIRNR003101}.
CC -!- SUBUNIT: Self-interacts. Interacts with FtsZ. {ECO:0000256|HAMAP-
CC Rule:MF_02033}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-
CC Rule:MF_02033}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_02033}; Cytoplasmic side {ECO:0000256|HAMAP-
CC Rule:MF_02033}. Note=Localizes to the Z ring in an FtsZ-dependent
CC manner. Targeted to the membrane through a conserved C-terminal
CC amphiphatic helix. {ECO:0000256|HAMAP-Rule:MF_02033}.
CC -!- SIMILARITY: Belongs to the FtsA/MreB family. {ECO:0000256|HAMAP-
CC Rule:MF_02033, ECO:0000256|PIRNR:PIRNR003101}.
CC -!- CAUTION: The sequence shown here is derived from an
CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC preliminary data. {ECO:0000313|EMBL:HAR68625.1}.
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DR EMBL; DMVK01000083; HAR68625.1; -; Genomic_DNA.
DR EMBL; PELP01000310; RTH02744.1; -; Genomic_DNA.
DR EMBL; PELM01000111; RTH03638.1; -; Genomic_DNA.
DR EMBL; PELR01000044; RTH06179.1; -; Genomic_DNA.
DR EMBL; PELV01000410; RTH14351.1; -; Genomic_DNA.
DR EMBL; PELW01000374; RTH22247.1; -; Genomic_DNA.
DR EMBL; PELY01000007; RTH28787.1; -; Genomic_DNA.
DR EMBL; PEMD01000322; RTH29521.1; -; Genomic_DNA.
DR EMBL; PELZ01000472; RTH31823.1; -; Genomic_DNA.
DR EMBL; PEMN01000222; RTI16403.1; -; Genomic_DNA.
DR EMBL; PEMJ01000033; RTI17407.1; -; Genomic_DNA.
DR EMBL; PEMW01000485; RTI47290.1; -; Genomic_DNA.
DR Proteomes; UP000286712; Unassembled WGS sequence.
DR Proteomes; UP000286734; Unassembled WGS sequence.
DR Proteomes; UP000286910; Unassembled WGS sequence.
DR Proteomes; UP000286928; Unassembled WGS sequence.
DR Proteomes; UP000287155; Unassembled WGS sequence.
DR Proteomes; UP000287306; Unassembled WGS sequence.
DR Proteomes; UP000287439; Unassembled WGS sequence.
DR Proteomes; UP000287467; Unassembled WGS sequence.
DR Proteomes; UP000288051; Unassembled WGS sequence.
DR Proteomes; UP000288073; Unassembled WGS sequence.
DR Proteomes; UP000288082; Unassembled WGS sequence.
DR GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR HAMAP; MF_02033; FtsA; 1.
DR InterPro; IPR020823; Cell_div_FtsA.
DR InterPro; IPR003494; SHS2_FtsA.
DR Pfam; PF02491; SHS2_FTSA; 1.
DR PIRSF; PIRSF003101; FtsA; 1.
DR SMART; SM00842; FtsA; 1.
DR TIGRFAMs; TIGR01174; ftsA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_02033,
KW ECO:0000256|PIRNR:PIRNR003101};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_02033,
KW ECO:0000256|PIRNR:PIRNR003101, ECO:0000313|EMBL:HAR68625.1};
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_02033};
KW Complete proteome {ECO:0000313|Proteomes:UP000286712,
KW ECO:0000313|Proteomes:UP000286734, ECO:0000313|Proteomes:UP000286910,
KW ECO:0000313|Proteomes:UP000286928};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_02033}.
FT DOMAIN 3 190 FtsA. {ECO:0000259|SMART:SM00842}.
SQ SEQUENCE 414 AA; 44233 MW; A630A55272E27A4F CRC64;
MIIAGLDVGT SKVTTVIGEL APDGVLDIIG EGNVPSQGLK RGVVVNLERT TEAIRQSVHQ
AERVAGVKVE RVILGVGGPH LKSVTSHGLA AIRRGQSISA ADVERAIEQA KAYPFDTDLE
LLHALPLEFK VDGQEGIRDP VGMAGVRLEV DVHLVAAGRG PLANLRRAVG EAGLEIEALV
AQPLASGLGV LSPEEEHMTV LLLDVGGGTT EVAVFREGRL AHSSVLPLGG DHVTQDIAQL
LKIPFEEAER VKRKYGAALP ELADPELVLE INQEGGSLGE VPAPELARII RPRLREILHL
ARQSVDEALG PLEIKVNRVI LTGGSALLKG FDLLARQQYG LPVRVGKPHG VSGLTDVVAT
PAHATAVGLV RYATTLPLTA PEPRRARERR ERREEKAKGE GLWARIKEIL NNLF
//